PC711100UL
MilliporeSigma™ anti-CHIP, Polyclonal
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PC711100UL-Each-of-1 | In Stock | ₹ 47,563.66 |
PC711100UL - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,563.66
GST (18%): ₹ 8,561.459
Total Price: ₹ 56,125.119
Antigen
CHIP
Classification
Polyclonal
Formulation
Undiluted serum.
Immunogen
a recombinant protein consisting of full-length human CHIP fused to a His·Tag™ sequence
Regulatory Status
RUO
Test Specificity
Recognizes the ∽35kDa CHIP protein. May also detect bands at ∽43, ∽51, and ∽70kDa corresponding to the mono-ubiquitinated, di-ubiquitinated, and dimeric forms of CHIP, respectively.
Content And Storage
−20°C
Isotype
IgG
Applications
Immunofluorescence, Immunoprecipitation
Conjugate
Unconjugated
Host Species
Rabbit
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Drosophila, Hamster, Human, Monkey, Mouse, Rat
Form
Undiluted
Related Products
Description
- Specifically detects CHIP Clone: in Drosophila, Hamster, Human, Monkey, Mouse, Rat samples, and it is validated for Immunofluorescence, Immunoprecipitation CHIP is a U-box dependent E3 ubiquitin ligase and a co-chaperone protein that interacts with Hsc70 and Hsp90 regulating protein triage decisions between folding and degradation
- This occurs through CHIP remodeling the complexes to favor substrate degradation thus providing a molecular link between the chaperone and proteosome machinery
- CHIP has been reported to be involved in the degradation of c-ErbB2/c-Neu, the glucocorticoid receptor, and the cystic fibrosis transmembrane-conductance regulator
- CHIP expression shortens the half-life of both the nascent and mature ErbB2 protein.
Compare Similar Items
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Antigen: CHIP
Classification: Polyclonal
Formulation: Undiluted serum.
Immunogen: a recombinant protein consisting of full-length human CHIP fused to a His·Tag™ sequence
Regulatory Status: RUO
Test Specificity: Recognizes the ∽35kDa CHIP protein. May also detect bands at ∽43, ∽51, and ∽70kDa corresponding to the mono-ubiquitinated, di-ubiquitinated, and dimeric forms of CHIP, respectively.
Content And Storage: −20°C
Isotype: IgG
Applications: Immunofluorescence, Immunoprecipitation
Conjugate: Unconjugated
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Drosophila, Hamster, Human, Monkey, Mouse, Rat
Form: Undiluted
Antigen:
CHIP
Classification:
Polyclonal
Formulation:
Undiluted serum.
Immunogen:
a recombinant protein consisting of full-length human CHIP fused to a His·Tag™ sequence
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽35kDa CHIP protein. May also detect bands at ∽43, ∽51, and ∽70kDa corresponding to the mono-ubiquitinated, di-ubiquitinated, and dimeric forms of CHIP, respectively.
Content And Storage:
−20°C
Isotype:
IgG
Applications:
Immunofluorescence, Immunoprecipitation
Conjugate:
Unconjugated
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Drosophila, Hamster, Human, Monkey, Mouse, Rat
Form:
Undiluted
Antigen: IDE, N-Terminal (97-273)
Classification: Polyclonal
Formulation: Undiluted serum.
Immunogen: a recombinant protein consisting of amino acids 97-273 of rat IDE fused to GST
Regulatory Status: RUO
Test Specificity: Recognizes the ∽115kDa endogenous and recombinant IDE.
Content And Storage: ≤ -70°C
Isotype: IgG
Applications: ELISA, Immunoblot, Immunoblot, Immunocytochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Hamster, Human, Mouse, Rat
Form: Serum
Antigen:
IDE, N-Terminal (97-273)
Classification:
Polyclonal
Formulation:
Undiluted serum.
Immunogen:
a recombinant protein consisting of amino acids 97-273 of rat IDE fused to GST
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽115kDa endogenous and recombinant IDE.
Content And Storage:
≤ -70°C
Isotype:
IgG
Applications:
ELISA, Immunoblot, Immunoblot, Immunocytochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Hamster, Human, Mouse, Rat
Form:
Serum
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