PI700366
RIG-I Recombinant Rabbit Monoclonal Antibody (35H2L48), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PI700366-Each-of-1 | In Stock | ₹ 55,143.42 |
PI700366 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,143.42
GST (18%): ₹ 9,925.816
Total Price: ₹ 65,069.236
Antigen
RIG-I
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
O95786, Q6Q899
Gene Symbols
DDX58
Immunogen
A recombinant protein corresponding to amino acids 454-600 of O95786.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
35H2L48
Conjugate
Unconjugated
Gene
DDX58
Gene Alias
6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
230073, 23586
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody is predicted to react with mouse based on sequence homology
- Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Retinoic acid-inducible gene I, RIG-I is a pattern recognition receptor (PRR) involved in the recognition of viral dsRNA
- Along with MDA5, RIG-I detects viral dsRNA and activates the innate immune response
- Both MDA5 and RIG-I are RNA helicases and they perform overlapping as well as distinct roles
- RIG-I is activated by dsRNAs without a 5'-triphosphate end and short dsRNAs, whereas MDA5 is activated by long dsRNAs
- Once activated, both proteins signal through IPS-1 activating transcription factors NF-kappaB and IRF-3 (1) and μgtimately activating apoptosis, cytokine signaling, and inflammation
- RIG-I is essential for signaling by influenza A, influenza B, human respiratory syncytial virus (3), paromyxoviruses, Japanese encephalitis virus, and West Nile virus
- MicroRNA-146a has been implicated in feedback inhibition of RIG-I-dependant antiviral response by negatively regulating RIG-I targets TRAF6, IRAK1, and IRAK2
- Recent evidence has implicated RIG-I in the detection of cytosolic DNA through RNA polymerase III activity.
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Antigen: RIG-I
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: O95786, Q6Q899
Gene Symbols: DDX58
Immunogen: A recombinant protein corresponding to amino acids 454-600 of O95786.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 35H2L48
Conjugate: Unconjugated
Gene: DDX58
Gene Alias: 6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 230073, 23586
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
RIG-I
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
O95786, Q6Q899
Gene Symbols:
DDX58
Immunogen:
A recombinant protein corresponding to amino acids 454-600 of O95786.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
35H2L48
Conjugate:
Unconjugated
Gene:
DDX58
Gene Alias:
6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
230073, 23586
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Connexin 46
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q64448
Gene Symbols: GJA3
Immunogen: A peptide corresponding to amino acids 131-144 of Q64448.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 11H16L33
Conjugate: Unconjugated
Gene: GJA3
Gene Alias: alpha 3 connexin; Cnx46; connexin 46; connexin-46; CTRCT14; Cx43; CX46; Cxn-46; CZP3; gap junction alpha 3; gap junction alpha-3 protein; gap junction membrane channel protein alpha 3; gap junction protein alpha 3; gap junction protein, alpha 3; gap junction protein, alpha 3, 46kDa; Gja3; Gja-3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 14611
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Connexin 46
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q64448
Gene Symbols:
GJA3
Immunogen:
A peptide corresponding to amino acids 131-144 of Q64448.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
11H16L33
Conjugate:
Unconjugated
Gene:
GJA3
Gene Alias:
alpha 3 connexin; Cnx46; connexin 46; connexin-46; CTRCT14; Cx43; CX46; Cxn-46; CZP3; gap junction alpha 3; gap junction alpha-3 protein; gap junction membrane channel protein alpha 3; gap junction protein alpha 3; gap junction protein, alpha 3; gap junction protein, alpha 3, 46kDa; Gja3; Gja-3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
14611
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Phospho-AKT1 (Ser473)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P31749, P31750
Gene Symbols: AKT1
Immunogen: A peptide corresponding to amino acids 468-477 of P31749.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 98H9L8
Conjugate: Unconjugated
Gene: AKT1
Gene Alias: Akt; Akt kinase; AKT serine/threonine kinase 1; Akt/PKB; akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; dPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; P-AKT; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; protein kinase B; Protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine protein kinase; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; SD10374p; serine/threonine protein kinase; serine-threonine protein kinase; Thymoma viral proto-oncogene; thymoma viral proto-oncogene 1; v-akt murine thymoma viral oncogene homolog 1; v-akt murine thymoma viral oncogene-like protein 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 11651, 207
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-AKT1 (Ser473)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P31749, P31750
Gene Symbols:
AKT1
Immunogen:
A peptide corresponding to amino acids 468-477 of P31749.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
98H9L8
Conjugate:
Unconjugated
Gene:
AKT1
Gene Alias:
Akt; Akt kinase; AKT serine/threonine kinase 1; Akt/PKB; akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; dPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; P-AKT; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; protein kinase B; Protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine protein kinase; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; SD10374p; serine/threonine protein kinase; serine-threonine protein kinase; Thymoma viral proto-oncogene; thymoma viral proto-oncogene 1; v-akt murine thymoma viral oncogene homolog 1; v-akt murine thymoma viral oncogene-like protein 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
11651, 207
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Phospho-IR/IGF1R (Tyr1162, Tyr1163)
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P06213, P08069
Gene Symbols: IGF1R, Insr
Immunogen: A peptide corresponding to amino acids 1186-1197 and 1162-1173 of P06213 and P08069, respectively
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Western Blot
Clone: 97H9L7
Conjugate: Unconjugated
Gene: IGF1R
Gene Alias: 4932439J01Rik; A330103N21Rik; CD220; CD221; D630014A15Rik; D930020L01; HHF5; hyft; IGF1 Receptor; IGF-1 receptor; IGF1 Receptor beta; Igf1r; IGF-1R; IGF1R beta; IGF-I receptor; IGF-I Receptor beta; IGFIR; IGFIRC; IGFR; Igfr1; Insr; insulin like growth factor 1 receptor; insulin receptor; insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; Insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor receptor type 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; IR; IR-A; IR-B; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3480, 3643
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-IR/IGF1R (Tyr1162, Tyr1163)
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P06213, P08069
Gene Symbols:
IGF1R, Insr
Immunogen:
A peptide corresponding to amino acids 1186-1197 and 1162-1173 of P06213 and P08069, respectively
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Western Blot
Clone:
97H9L7
Conjugate:
Unconjugated
Gene:
IGF1R
Gene Alias:
4932439J01Rik; A330103N21Rik; CD220; CD221; D630014A15Rik; D930020L01; HHF5; hyft; IGF1 Receptor; IGF-1 receptor; IGF1 Receptor beta; Igf1r; IGF-1R; IGF1R beta; IGF-I receptor; IGF-I Receptor beta; IGFIR; IGFIRC; IGFR; Igfr1; Insr; insulin like growth factor 1 receptor; insulin receptor; insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; Insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor receptor type 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; IR; IR-A; IR-B; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3480, 3643
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid