PI702383

Phospho-Syk (Tyr323, Tyr317) Recombinant Rabbit Monoclonal Antibody (6H48L23), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PI702383-Each-of-1 In Stock ₹ 46,501.86

PI702383 - Each of 1

₹ 46,501.86

In Stock

Quantity

1

Base Price: ₹ 46,501.86

GST (18%): ₹ 8,370.335

Total Price: ₹ 54,872.195

Antigen

Phospho-Syk (Tyr323, Tyr317)

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

P43405

Gene Symbols

Syk

Immunogen

Peptide corresponding to Human Syk (aa 319-327)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

6H48L23

Conjugate

Unconjugated

Gene

Syk

Gene Alias

DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

6850

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with Monkey, Horse, Cat, Mouse and Rat Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Spleen tyrosine kinase (SYK), along with ZAP70, are cytoplasmic tyrosine kinases that are viewed as potential druge targets for allergic disorders and autoimmune diseases
  • SYK may also play a role in cancer
  • Syk translocates to the plasma membrane upon B cell antigen receptor (BCR) or the high-affinity IgE receptor (FcepsilonRI) triggering, and phosphorylates downstream adaptor proteins, thereby providing docking sites for initiation of subsequent signaling pathways, such as calcium mobilization, cytoskeleton remodeling, or transcription of specific genes
  • Syk binds to the receptor assemblies through interactions of its pair of SH2 domains with ITAM motives of the receptor, which have been phosphorylated by Src-family kinases
  • These kinases also help to activate Syk by phosphorylation of its activation loop.

Compare Similar Items

Show Difference

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Thermo Scientific

PI702383

--


Antigen:
Phospho-Syk (Tyr323, Tyr317)

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
P43405

Gene Symbols:
Syk

Immunogen:
Peptide corresponding to Human Syk (aa 319-327)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
6H48L23

Conjugate:
Unconjugated

Gene:
Syk

Gene Alias:
DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6850

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Thermo Scientific

PI702386

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Antigen:
Phospho-Paxillin (Ser178)

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P49023

Gene Symbols:
PXN

Immunogen:
Peptide corresponding to Human PXN (aa 173-181)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
21H7L6

Conjugate:
Unconjugated

Gene:
PXN

Gene Alias:
adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; pxn; pxna; testicular tissue protein Li 134; TGFB1I1; transforming growth factor beta 1 induced transcript 1; wu:fw71f12

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5829

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PI702389

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Antigen:
Puromycin N-acetyltransferase

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Protein corresponding to Streptomyces alboniger Pac (aa 1-199)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
1H12L8

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Puromycin N-acetyl-transferase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PI702392

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Antigen:
NDE1

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q9CZA6, Q9ES39, Q9NXR1

Gene Symbols:
NDE1

Immunogen:
Protein corresponding to human NDE1 (aa1-aa346)

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
22H20L67

Conjugate:
Unconjugated

Gene:
NDE1

Gene Alias:
2810027M15Rik; AU042936; AW822251; HOM-TES-87; LIS1-interacting protein NUDE1; LIS1-interacting protein NUDE1, rat homolog; LIS4; MHAC; mNudE; NDE; NDE1; nuclear distribution gene E homolog 1; nuclear distribution gene E homolog 1 (A nidulans); nuclear distribution protein nudE homolog 1; NudE; nudE neurodevelopment protein 1; nudE nuclear distribution E homolog 1; nudE nuclear distribution gene E homolog 1; Nude1; rNudE

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
54820, 67203, 83836

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid