PI702653

MSK1 Recombinant Rabbit Monoclonal Antibody (4H15L51), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PI702653-Each-of-1 In Stock ₹ 53,817.24

PI702653 - Each of 1

₹ 53,817.24

In Stock

Quantity

1

Base Price: ₹ 53,817.24

GST (18%): ₹ 9,687.103

Total Price: ₹ 63,504.343

Antigen

MSK1

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

O75582

Gene Symbols

Rps6ka5

Immunogen

Peptides corresponding to human MSK1 [1) aa742-aa758, 2) aa773-aa792]

Quantity

100μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

4H15L51

Conjugate

Unconjugated

Gene

Rps6ka5

Gene Alias

3110005L17Rik; 6330404E13Rik; 90 kDa ribosomal protein S6 kinase 5; AI854034; kinase MSK1; KS6A5; mitogen and stress-activated protein kinase 1; Msk1; MSPK1; Nuclear mitogen- and stress-activated protein kinase 1; ribosomal protein S6 kinase A5; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; ribosomal protein S6 kinase, polypeptide 5; RLPK; RLSK; Rps6ka5; RSKL; RSK-like protein kinase; S6K-alpha-5

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

9252

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody is predicted to react with Monkey, Pig, Rat, and Mouse
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • RPS6KA5 (MSK1) is a serine/threonine protein kinase that is essential for the regulation of various cellular processes
  • RPS6KA5 is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes
  • Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin
  • Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression
  • In skeletal myoblasts is required for phosphorylation of RELA at 'Ser-276' during oxidative stress
  • In erythropoietin-stimulated cells, is necessary for the 'Ser-727' phosphorylation of STAT3 and regulation of its transcriptional potential.

Compare Similar Items

Show Difference

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Thermo Scientific

PI702653

--


Antigen:
MSK1

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
O75582

Gene Symbols:
Rps6ka5

Immunogen:
Peptides corresponding to human MSK1 [1) aa742-aa758, 2) aa773-aa792]

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
4H15L51

Conjugate:
Unconjugated

Gene:
Rps6ka5

Gene Alias:
3110005L17Rik; 6330404E13Rik; 90 kDa ribosomal protein S6 kinase 5; AI854034; kinase MSK1; KS6A5; mitogen and stress-activated protein kinase 1; Msk1; MSPK1; Nuclear mitogen- and stress-activated protein kinase 1; ribosomal protein S6 kinase A5; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; ribosomal protein S6 kinase, polypeptide 5; RLPK; RLSK; Rps6ka5; RSKL; RSK-like protein kinase; S6K-alpha-5

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9252

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PI702683

--


Antigen:
ILK

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q13418

Gene Symbols:
ILK

Immunogen:
Protein corresponding to Human ILK (aa 1-300)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
14H10L20

Conjugate:
Unconjugated

Gene:
ILK

Gene Alias:
59 kDa serine/threonine-protein kinase; AA511515; epididymis secretory protein Li 28; ESTM24; HEL-S-28; ILK; ILK1; ILK-1; ILK2; ILK-2; integrin binding protein kinase; Integrin linked ILK; integrin linked kinase; integrin-linked kinase; integrin-linked kinase-2; integrin-linked protein kinase; loc; lost-contact; main squeeze; msq; P59; p59ILK; zgc:65842; zilk

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3611

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PI702720

--


Antigen:
AGO1

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q9UL18

Gene Symbols:
Ago1

Immunogen:
Peptides corresponding to human AGO1 (1) aa17-aa35 2) aa382-aa401)

Quantity:
100μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
6H1L4

Conjugate:
Unconjugated

Gene:
Ago1

Gene Alias:
AGO1; argonaute 1; argonaute 1, RISC catalytic component; argonaute RISC catalytic component 1; argonaute RISC catalytic subunit 1; argonaute1; EIF2C; eIF2C 1; eIF-2C 1; EIF2C1; Eukaryotic translation initiation factor 2C 1; eukaryotic translation initiation factor 2C, 1; GERP95; Golgi Endoplasmic Reticulum protein 95 kDa; hAgo1; mAgo1; Piwi/Argonaute family protein meIF2C1; Protein argonaute-1; putative RNA-binding protein Q99; Q99

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
26523

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PI702764

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Antigen:
FOXN3

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
O00409

Gene Symbols:
Foxn3

Immunogen:
Peptides corresponding to human FOXN3 ICC/FC Sp (aa381-398, aa440-455)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Immunocytochemistry

Clone:
1H2L8

Conjugate:
Unconjugated

Gene:
Foxn3

Gene Alias:
5430426H20Rik; AA589593; AW556347; C14orf116; checkpoint suppressor 1; CHES; Ches1; Ches1l; forkhead box N3; forkhead box protein N3; Foxn3; HTLFL1; PRO1635

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1112

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid