PIMA529584

MST1 (STK4) Monoclonal Antibody (01), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA529584-Each-of-1 In Stock ₹ 31,143.84

PIMA529584 - Each of 1

₹ 31,143.84

In Stock

Quantity

1

Base Price: ₹ 31,143.84

GST (18%): ₹ 5,605.891

Total Price: ₹ 36,749.731

Antigen

MST1 (STK4)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q13043

Gene Symbols

Stk4

Immunogen

Recombinant Human STK4/MST1 protein (Glu2-Phe487)

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunocytochemistry

Clone

01

Conjugate

Unconjugated

Gene

Stk4

Gene Alias

AI447339; AU020804; EC 2.7.11.1; Kas-2; kinase MST1; kinase responsive to stress 2; KRS2; Mammalian STE20-like protein kinase 1; mammalian sterile 20-like 1; MST1; MST-1; MST1/C; MST1/N; serine/threonine kinase 4; serine/threonine-protein kinase 4; Serine/threonine-protein kinase 4 18kDa subunit; Serine/threonine-protein kinase 4 37kDa subunit; Serine/threonine-protein kinase Krs-2; STE20-like kinase MST1; sterile 20-like kinase 1; STK4; TIIAC; Yeast Sps1/Ste20-related kinase 3; Ysk3

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

6789

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • This antibody has specificity for Human STK4/MST1
  • STK4 (MST1) is a serine/threonine kinase which may be involved in apoptosis
  • It is possible that this protein induces the chromatin condensation observed in this process
  • STK4 is a stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation
  • It is a key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
  • The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
  • Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration
  • STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation.

Compare Similar Items

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Img

Thermo Scientific

PIMA529584

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Antigen:
MST1 (STK4)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q13043

Gene Symbols:
Stk4

Immunogen:
Recombinant Human STK4/MST1 protein (Glu2-Phe487)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry

Clone:
01

Conjugate:
Unconjugated

Gene:
Stk4

Gene Alias:
AI447339; AU020804; EC 2.7.11.1; Kas-2; kinase MST1; kinase responsive to stress 2; KRS2; Mammalian STE20-like protein kinase 1; mammalian sterile 20-like 1; MST1; MST-1; MST1/C; MST1/N; serine/threonine kinase 4; serine/threonine-protein kinase 4; Serine/threonine-protein kinase 4 18kDa subunit; Serine/threonine-protein kinase 4 37kDa subunit; Serine/threonine-protein kinase Krs-2; STE20-like kinase MST1; sterile 20-like kinase 1; STK4; TIIAC; Yeast Sps1/Ste20-related kinase 3; Ysk3

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6789

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA529587

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Antigen:
STUB1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q9UNE7

Gene Symbols:
STUB1

Immunogen:
Recombinant Human STUB1 protein

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
034

Conjugate:
Unconjugated

Gene:
STUB1

Gene Alias:
0610033N24Rik; 2210017D18Rik; 2310040B03Rik; Antigen NY-CO-7; AW046544; Carboxy terminus of Hsp70-interacting protein; CHIP; CLL-associated antigen KW-8; E3 ubiquitin-protein ligase CHIP; heat shock protein A binding protein 2 (c-terminal); HSPABP2; LA16c-313D11.6; NY-CO-7; PP1131; RING-type E3 ubiquitin transferase CHIP; SCAR16; SDCCAG7; serologically defined colon cancer antigen 7; STIP1 homology and U box-containing protein 1; STIP1 homology and U-box containing protein 1; STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase; Stub1; UBOX1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10273

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA529589

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Antigen:
SULT1A1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P50225

Gene Symbols:
SULT1A1

Immunogen:
Recombinant Human SULT1A1 protein (Glu2-Leu295)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunoprecipitation, Western Blot

Clone:
3C5H6

Conjugate:
Unconjugated

Gene:
SULT1A1

Gene Alias:
AI266890; aryl sulfotransferase; Aryl sulfotransferase 1; Aryl sulfotransferase cytosolic 1A phenol-preferring member 3; Aryl sulfotransferase cytosolic, 1A, phenol-preferring, member 3; aryl sulfotransferase IV; arylsulfotransferase ST1A4; ASTIV; CSPS; HAST1/HAST2; MGC131921; MGC5163; Minoxidil sulfotransferase; mSTp1; Mx-ST; OK/SW-cl.88; OTTHUMP00000162568; OTTHUMP00000162569; P PST; P PST 1; Phenol sulfotransferase; Phenol sulfotransferase 1; Phenol sulfotransferase 1a1; phenol/aryl sulfotransferase; phenol-sulfating phenol sulfotransferase 1; P-PST; P-PST 1; PST; PST-1; St1a1; ST1A3; ST1A4; Stm; STP; STP1; sulfokinase; Sulfotransferase 1A1; sulfotransferase family 1A member 1; sulfotransferase family 1A, phenol-preferring, member 1; sulfotransferase family, cytosolic, 1A, phenol preferring; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1; sulfotransferase, phenol preferring 1; sulphotransferase family cytosolic 1A phenol-prefering member 1; SULT1A1; Sult1a3; The

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6817

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA529590

--


Antigen:
SULT1A1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P50225

Gene Symbols:
SULT1A1

Immunogen:
Recombinant Human SULT1A1 protein (Glu2-Leu295)

Quantity:
100μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
034

Conjugate:
Unconjugated

Gene:
SULT1A1

Gene Alias:
AI266890; aryl sulfotransferase; Aryl sulfotransferase 1; Aryl sulfotransferase cytosolic 1A phenol-preferring member 3; Aryl sulfotransferase cytosolic, 1A, phenol-preferring, member 3; aryl sulfotransferase IV; arylsulfotransferase ST1A4; ASTIV; CSPS; HAST1/HAST2; MGC131921; MGC5163; Minoxidil sulfotransferase; mSTp1; Mx-ST; OK/SW-cl.88; OTTHUMP00000162568; OTTHUMP00000162569; P PST; P PST 1; Phenol sulfotransferase; Phenol sulfotransferase 1; Phenol sulfotransferase 1a1; phenol/aryl sulfotransferase; phenol-sulfating phenol sulfotransferase 1; P-PST; P-PST 1; PST; PST-1; St1a1; ST1A3; ST1A4; Stm; STP; STP1; sulfokinase; Sulfotransferase 1A1; sulfotransferase family 1A member 1; sulfotransferase family 1A, phenol-preferring, member 1; sulfotransferase family, cytosolic, 1A, phenol preferring; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1; sulfotransferase, phenol preferring 1; sulphotransferase family cytosolic 1A phenol-prefering member 1; SULT1A1; Sult1a3; The

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6817

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid