PIMA110144

CD22 Monoclonal Antibody (IS7), FITC, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA110144-Each-of-1 In Stock ₹ 35,592.96

PIMA110144 - Each of 1

₹ 35,592.96

In Stock

Quantity

1

Base Price: ₹ 35,592.96

GST (18%): ₹ 6,406.733

Total Price: ₹ 41,999.693

Antigen

CD22

Classification

Monoclonal

Conjugate

FITC

Gene

CD22

Gene Alias

A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14

Host Species

Mouse

Purification Method

Size-exclusion chromatography

Regulatory Status

RUO

Gene ID (Entrez)

933

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

IS7

Formulation

PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.

P20273

Gene Symbols

CD22

Immunogen

Reh human cell line

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Description

  • CD22 (BL-CAM) is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140 kDa
  • CD22 is expressed in both the cytoplasm and cell membrane of B-lymphocytes
  • CD22 antigen appears early in B-cell lymphocyte differentiation at approximately the same stage as the CD19 antigen
  • Unlike other B-cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias
  • CD22 is also strongly expressed in hairy cell leukemia
  • CD22 preferentially binds to alpha2,6-linked sialic acid
  • The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface
  • Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B cell antigen receptor signaling
  • CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules
  • CD22 is also strongly expressed in hairy cell leukemia
  • CD22 is also positive in diffuse large B-cell lymphoma and nodular lymphocyte predominance Hodgkin’s lymphoma, but negative in classical Hodgkin’s lymphoma.

Compare Similar Items

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Img

Thermo Scientific

PIMA110144

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Antigen:
CD22

Classification:
Monoclonal

Conjugate:
FITC

Gene:
CD22

Gene Alias:
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; B-lymphocyte cell adhesion molecule (BL-CAM); Cd22; CD22 antigen; CD22 molecule; FLJ22814; Lectin 2; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2 (Siglec-2); Siglec2; Siglec-2; T-cell surface antigen Leu-14

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
933

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
IS7

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P20273

Gene Symbols:
CD22

Immunogen:
Reh human cell line

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA110146

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Antigen:
IGF2R

Classification:
Monoclonal

Conjugate:
APC

Gene:
IGF2R

Gene Alias:
300 kDa mannose 6-phosphate receptor; AI661837; cation-independent mannose 6-phosphate receptor; cation-independent mannose 6-phosphate receptor protein; cation-independent mannose-6-phosphate receptor; cation-independent MPR; CD222; CI Man-6-P receptor; CI-M6PR; CIMPR; CI-MPR; Igf2r; IGF-II receptor; IGF-II/CI-MPR; Igfr2; insulin like growth factor 2 receptor; insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; insulin-like growth factor receptor type 2; M6P; M6P/IGF2 receptor; M6P/IGF2R; M6PR; M6P-R; mannose-6-phosphate receptor, cation independent; mannose-6-phosphate/insulin-like growth factor II receptor; MPR 300; MPR1; MPR300; MPRI; similar to mannose-6-phosphate/insulin-like growth factor II receptor

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3482

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MEM-238

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P11717

Gene Symbols:
IGF2R

Immunogen:
Recombinant Vaccinia virus encoding CD222.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA110148

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Antigen:
IGF2R

Classification:
Monoclonal

Conjugate:
PE

Gene:
IGF2R

Gene Alias:
300 kDa mannose 6-phosphate receptor; AI661837; cation-independent mannose 6-phosphate receptor; cation-independent mannose 6-phosphate receptor protein; cation-independent mannose-6-phosphate receptor; cation-independent MPR; CD222; CI Man-6-P receptor; CI-M6PR; CIMPR; CI-MPR; Igf2r; IGF-II receptor; IGF-II/CI-MPR; Igfr2; insulin like growth factor 2 receptor; insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; insulin-like growth factor receptor type 2; M6P; M6P/IGF2 receptor; M6P/IGF2R; M6PR; M6P-R; mannose-6-phosphate receptor, cation independent; mannose-6-phosphate/insulin-like growth factor II receptor; MPR 300; MPR1; MPR300; MPRI; similar to mannose-6-phosphate/insulin-like growth factor II receptor

Host Species:
Mouse

Purification Method:
Size-exclusion chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3482

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MEM-238

Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P11717

Gene Symbols:
IGF2R

Immunogen:
Recombinant Vaccinia virus encoding CD222.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA110152

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Antigen:
PrP

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PRNP

Gene Alias:
AA960666; AI325101; Alternative prion protein; alternative prion protein; major prion protein; AltPrP; ASCR; BSE; CD230; CD230 antigen; CJD; GSS; KURU; major prion protein; major prion protein; alternative prion protein; major scrapie-associated fibril protein 1; MGC26679; p27-30; PK resistant core; prion protein; prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia); prion protein precursor; prion protein precursor PrP; prion protein PrP; prion protein variant a; prion protein variant b; prion protein, PrP; prion protein, structural; prion-related protein; PRIP; Prn; Prn-i; Prnp; Prn-p; PrP; PrP<C>; PrP27-30; PrP33-35C; PrPc; PrPSc; Sinc; SIP; TSE

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5621

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Western Blot

Clone:
EM-20

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
F7VJQ1, P04156

Gene Symbols:
PRNP

Immunogen:
Recombinant human prion protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a