PIMA1183
beta Arrestin 1 Monoclonal Antibody (4E11B1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA1183-Each-of-1 | In Stock | ₹ 47,785.26 |
PIMA1183 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,785.26
GST (18%): ₹ 8,601.347
Total Price: ₹ 56,386.607
Antigen
beta Arrestin 1
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P49407
Gene Symbols
ARRB1
Immunogen
Purified recombinant fragment of human ARRB1 (AA: 89-268) expressed in E Coli
Quantity
100μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Western Blot
Clone
4E11B1
Conjugate
Unconjugated
Gene
ARRB1
Gene Alias
1200006I17Rik; ARB1; ARR1; ARRB1; ARRB1 protein; arrdc1; arrestin; arrestin 2; arrestin beta 1; arrestin beta-1; arrestin, beta 1; arrestin-2; AW208571; BARRES; beta-arrestin; beta-arrestin1; beta-arrestin-1; G430100A01Rik; Non-visual arrestin-2
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
408
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-183 detects beta Arrestin 1 protein from human samples at approximately 55 kDa
- Beta Arrestin 1 is a member of a family of proteins widely expressed but especially abundant in the central nervous system
- Serving as an adaptor or scaffold molecule, beta Arrestin 1 is essential for mitogenic signaling and mediates agonist-dependent desensitization and internalization of Gprotein-coupled receptors (GPCRs, e.g., beta 2-adrenergic receptor)
- After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosphorylated by G-protein receptor kinases (GRKs) on serine residues
- Beta Arrestin 1 in the cytosol is phosphorylated by ERK1 and 2 on serine412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane
- Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to activation of the Ras, Raf, ERK1 and 2 signaling pathway.
Compare Similar Items
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Antigen: beta Arrestin 1
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P49407
Gene Symbols: ARRB1
Immunogen: Purified recombinant fragment of human ARRB1 (AA: 89-268) expressed in E Coli
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Western Blot
Clone: 4E11B1
Conjugate: Unconjugated
Gene: ARRB1
Gene Alias: 1200006I17Rik; ARB1; ARR1; ARRB1; ARRB1 protein; arrdc1; arrestin; arrestin 2; arrestin beta 1; arrestin beta-1; arrestin, beta 1; arrestin-2; AW208571; BARRES; beta-arrestin; beta-arrestin1; beta-arrestin-1; G430100A01Rik; Non-visual arrestin-2
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 408
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
beta Arrestin 1
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
P49407
Gene Symbols:
ARRB1
Immunogen:
Purified recombinant fragment of human ARRB1 (AA: 89-268) expressed in E Coli
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Western Blot
Clone:
4E11B1
Conjugate:
Unconjugated
Gene:
ARRB1
Gene Alias:
1200006I17Rik; ARB1; ARR1; ARRB1; ARRB1 protein; arrdc1; arrestin; arrestin 2; arrestin beta 1; arrestin beta-1; arrestin, beta 1; arrestin-2; AW208571; BARRES; beta-arrestin; beta-arrestin1; beta-arrestin-1; G430100A01Rik; Non-visual arrestin-2
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
408
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: NME2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P19804, P22392, Q01768
Gene Symbols: NME2
Immunogen: Purified, recombinant full length human NME2 (aa 1-152) expressed in E. Coli.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Western Blot
Clone: 4G7A8
Conjugate: Unconjugated
Gene: NME2
Gene Alias: 2.7.13.3; c-myc purine-binding transcription factor PUF; c-myc transcription factor; epididymis secretory sperm binding protein Li 155an; expressed in non-metastatic cells 2; expressed in non-metastatic cells 2 protein; HEL-S-155an; histidine protein kinase NDKB; NDK B; NDKB; NDP kinase alpha; NDP kinase B; NDPKB; NDPK-B; nm23-2; NM23B; nm23-H2; nm23-M2; NME/NM23 nucleoside diphosphate kinase 2; Nme2; non-metastatic cells 2, protein (NM23) expressed in; non-metastatic cells 2, protein (NM23B) expressed in; nucleoside diphosphate kinase B; nucleoside-diphosphate kinase 2; nucleotide diphosphate kinase B; P18; p18-12d; PUF
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18103, 4831, 83782
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
NME2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P19804, P22392, Q01768
Gene Symbols:
NME2
Immunogen:
Purified, recombinant full length human NME2 (aa 1-152) expressed in E. Coli.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Western Blot
Clone:
4G7A8
Conjugate:
Unconjugated
Gene:
NME2
Gene Alias:
2.7.13.3; c-myc purine-binding transcription factor PUF; c-myc transcription factor; epididymis secretory sperm binding protein Li 155an; expressed in non-metastatic cells 2; expressed in non-metastatic cells 2 protein; HEL-S-155an; histidine protein kinase NDKB; NDK B; NDKB; NDP kinase alpha; NDP kinase B; NDPKB; NDPK-B; nm23-2; NM23B; nm23-H2; nm23-M2; NME/NM23 nucleoside diphosphate kinase 2; Nme2; non-metastatic cells 2, protein (NM23) expressed in; non-metastatic cells 2, protein (NM23B) expressed in; nucleoside diphosphate kinase B; nucleoside-diphosphate kinase 2; nucleotide diphosphate kinase B; P18; p18-12d; PUF
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18103, 4831, 83782
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Progranulin
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
Gene Accession No.: P28799
Gene Symbols: GRN
Immunogen: Recombinant human Progranulin
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone: 2D4-2F1
Conjugate: Unconjugated
Gene: GRN
Gene Alias: Acrogranin; acrogranulin; CLN11; epithelin; Epithelin precursor; Epithelin/granulin precursor; Epithelin-1; Epithelin-2; GEP; Glycoprotein of 88 Kda; GP88; granulin; Granulin A; Granulin B; Granulin C; Granulin D; Granulin E; Granulin F; Granulin G; Granulin precursor; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7; granulin-epithelin; granulins; GRN; Paragranulin; PC cell-derived growth factor; PCDGF; PEPI; Pgrn; Proepithelin; progranulin
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2896
Content And Storage: -20°C
Form: Liquid
Antigen:
Progranulin
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
Gene Accession No.:
P28799
Gene Symbols:
GRN
Immunogen:
Recombinant human Progranulin
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone:
2D4-2F1
Conjugate:
Unconjugated
Gene:
GRN
Gene Alias:
Acrogranin; acrogranulin; CLN11; epithelin; Epithelin precursor; Epithelin/granulin precursor; Epithelin-1; Epithelin-2; GEP; Glycoprotein of 88 Kda; GP88; granulin; Granulin A; Granulin B; Granulin C; Granulin D; Granulin E; Granulin F; Granulin G; Granulin precursor; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7; granulin-epithelin; granulins; GRN; Paragranulin; PC cell-derived growth factor; PCDGF; PEPI; Pgrn; Proepithelin; progranulin
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2896
Content And Storage:
-20°C
Form:
Liquid
Antigen: PGF
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
Gene Accession No.: P49763
Gene Symbols: PGF
Immunogen: Human recombinant Placental Growth Factor-1
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a κ
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 24G3
Conjugate: Unconjugated
Gene: PGF
Gene Alias: AI854365; D12S1900; PGF; PGFL; PIGF; Placenta growth factor; placental growth factor; placental growth factor, vascular endothelial growth factor-related protein; Plgf; PlGF 1; PlGF-2; SHGC; SHGC-10760
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5228
Content And Storage: -20°C
Form: Liquid
Antigen:
PGF
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
Gene Accession No.:
P49763
Gene Symbols:
PGF
Immunogen:
Human recombinant Placental Growth Factor-1
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
24G3
Conjugate:
Unconjugated
Gene:
PGF
Gene Alias:
AI854365; D12S1900; PGF; PGFL; PIGF; Placenta growth factor; placental growth factor; placental growth factor, vascular endothelial growth factor-related protein; Plgf; PlGF 1; PlGF-2; SHGC; SHGC-10760
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5228
Content And Storage:
-20°C
Form:
Liquid