PIMA123336
Chk1 Monoclonal Antibody (6F5), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA123336-Each-of-1 | In Stock | ₹ 51,250.44 |
PIMA123336 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,250.44
GST (18%): ₹ 9,225.079
Total Price: ₹ 60,475.519
Antigen
Chk1
Classification
Monoclonal
Concentration
3.15 mg/mL
Formulation
PBS with 20% glycerol and no preservative; pH 7
Gene Accession No.
O14757, O35280
Gene Symbols
Chek1
Immunogen
Full-length human Chk1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
6F5
Conjugate
Unconjugated
Gene
Chek1
Gene Alias
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
1111, 12649
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA1-23336 detects Chk1 in Human samples
- CHEK1 (CHK1) is a serine/threonine protein kinase involved in preventing replication when DNA integrity is compromised
- CHK1 is a key mediator in the DNA damage-induced checkpoint network
- CHK1 is an evolutionarily conserved protein kinase that functions to ensure genomic integrity upon genotoxic stress
- When the G2 or S checkpoint is abrogated by the inhibition of CHK1, p53-deficient cancer cells undergo mitotic catastrophe and eventually apoptosis, whereas normal cells are still arrested in the G1 phase
- Thus, CHK1 inhibitors can preferentially potentiate the efficacy of DNA damaging agents in cancer cells, and Chk1 is an attractive therapeutic target for cancer treatment, especially since approximately 50% of all human cancers are p53-deficient.
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Antigen: Chk1
Classification: Monoclonal
Concentration: 3.15 mg/mL
Formulation: PBS with 20% glycerol and no preservative; pH 7
Gene Accession No.: O14757, O35280
Gene Symbols: Chek1
Immunogen: Full-length human Chk1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: 6F5
Conjugate: Unconjugated
Gene: Chek1
Gene Alias: C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 1111, 12649
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Chk1
Classification:
Monoclonal
Concentration:
3.15 mg/mL
Formulation:
PBS with 20% glycerol and no preservative; pH 7
Gene Accession No.:
O14757, O35280
Gene Symbols:
Chek1
Immunogen:
Full-length human Chk1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
6F5
Conjugate:
Unconjugated
Gene:
Chek1
Gene Alias:
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
1111, 12649
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: RAD54L
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: Q92698
Gene Symbols: RAD54L
Immunogen: Synthetic peptide - Combination of N & C peptide - Corresponding to a range between amino acids 1-300 and 450-741
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Western Blot
Clone: 60.1
Conjugate: Unconjugated
Gene: RAD54L
Gene Alias: ATR2; DNA repair and recombination protein RAD54-like; h hRAD54; hHR54; HR54; hRAD54; MGC2094; mHR54; mRAD54; MRXHF1; Rad54; RAD54 homolog; RAD54 like (S. cerevisiae); RAD54A; RAD54L; RAD54-like (S. cerevisiae); RP5-875J14.1; SFM1; SHS; XH2; XNP; ZNF-HX
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 8438
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
RAD54L
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
Q92698
Gene Symbols:
RAD54L
Immunogen:
Synthetic peptide - Combination of N & C peptide - Corresponding to a range between amino acids 1-300 and 450-741
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Western Blot
Clone:
60.1
Conjugate:
Unconjugated
Gene:
RAD54L
Gene Alias:
ATR2; DNA repair and recombination protein RAD54-like; h hRAD54; hHR54; HR54; hRAD54; MGC2094; mHR54; mRAD54; MRXHF1; Rad54; RAD54 homolog; RAD54 like (S. cerevisiae); RAD54A; RAD54L; RAD54-like (S. cerevisiae); RP5-875J14.1; SFM1; SHS; XH2; XNP; ZNF-HX
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
8438
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: FANCD2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.2
Gene Accession No.: Q9BXW9
Gene Symbols: FANCD2
Immunogen: Human FANCD2 fusion protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: 6
Conjugate: Unconjugated
Gene: FANCD2
Gene Alias: 2410150O07Rik; AU015151; BB137857; DKFZp762A223; FA4; FACD; FACD2; FAD; FAD2; FA-D2; FANCD; FANCD2; Fanconi anemia complementation group D2; Fanconi anemia D2 protein; Fanconi anemia group D2 protein; Fanconi anemia group D2 protein homolog; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 2177
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
FANCD2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.2
Gene Accession No.:
Q9BXW9
Gene Symbols:
FANCD2
Immunogen:
Human FANCD2 fusion protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
6
Conjugate:
Unconjugated
Gene:
FANCD2
Gene Alias:
2410150O07Rik; AU015151; BB137857; DKFZp762A223; FA4; FACD; FACD2; FAD; FAD2; FA-D2; FANCD; FANCD2; Fanconi anemia complementation group D2; Fanconi anemia D2 protein; Fanconi anemia group D2 protein; Fanconi anemia group D2 protein homolog; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
2177
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CD14
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.: P08571
Gene Symbols: Cd14
Immunogen: Monocytes (Human)
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry
Clone: B365.1 (B-A8)
Conjugate: Unconjugated
Gene: Cd14
Gene Alias: CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; monocyte differentiation antigen CD14; LOW QUALITY PROTEIN: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 929
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD14
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P08571
Gene Symbols:
Cd14
Immunogen:
Monocytes (Human)
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry
Clone:
B365.1 (B-A8)
Conjugate:
Unconjugated
Gene:
Cd14
Gene Alias:
CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; monocyte differentiation antigen CD14; LOW QUALITY PROTEIN: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
929
Content And Storage:
4° C, do not freeze
Form:
Liquid