PIMA124704

Caspase 12 Monoclonal Antibody (14F7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA124704-Each-of-1 In Stock ₹ 45,646.26

PIMA124704 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

Caspase 12

Classification

Monoclonal

Concentration

2.2 mg/mL

Formulation

0.01M PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

O08736, Q920D5

Gene Symbols

CASP12

Immunogen

Recombinant fragment corresponding to residues 95-318 of mouse Caspase 12.

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG2a

Applications

Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone

14F7

Conjugate

Unconjugated

Gene

CASP12

Gene Alias

CASP12; CASP-12; CASP12P1; caspase 12; caspase 12 (gene/pseudogene); caspase 12 pseudogene 1; caspase-12; Inactive caspase-12; OTTMUSP00000045799; OTTMUSP00000045802; OTTMUSP00000045803; UNQ9415; UNQ9415/PRO34398

Host Species

Rat

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

12364, 156117

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recommended positive controls: NRK
  • Three distinct signaling pathways lead to programmed cell death (apoptosis)
  • The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved
  • The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved
  • Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion
  • Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis
  • Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including -gamma-secretase presenilin and beta-amyloid precursor protein (APP)
  • Caspase-12 mediates cytotoxicity induced by amyloid-beta
  • Caspase-12 is ubiquitously expressed in mouse tissues.

Compare Similar Items

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Img

Thermo Scientific

PIMA124704

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Antigen:
Caspase 12

Classification:
Monoclonal

Concentration:
2.2 mg/mL

Formulation:
0.01M PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
O08736, Q920D5

Gene Symbols:
CASP12

Immunogen:
Recombinant fragment corresponding to residues 95-318 of mouse Caspase 12.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
14F7

Conjugate:
Unconjugated

Gene:
CASP12

Gene Alias:
CASP12; CASP-12; CASP12P1; caspase 12; caspase 12 (gene/pseudogene); caspase 12 pseudogene 1; caspase-12; Inactive caspase-12; OTTMUSP00000045799; OTTMUSP00000045802; OTTMUSP00000045803; UNQ9415; UNQ9415/PRO34398

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
12364, 156117

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA124723

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Antigen:
TNFR2

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P20333

Gene Symbols:
Tnfrsf1b

Immunogen:
Recombinant human sTNF-RII, expressed in E. coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunocytochemistry, Neutralization

Clone:
22221.311

Conjugate:
Unconjugated

Gene:
Tnfrsf1b

Gene Alias:
CD120b; Etanercept; p75; p75 TNF receptor; p75 TNFR; p75TNFR; p80 TNF-alpha receptor; sCD120b; soluble CD120b; soluble TNFR1B variant 1; soluble TNFR2; sTNF R2; sTNFR 2; sTNFR2; TBP-2; TBPII; TNF receptor beta chain; TNF receptor superfamily member 1B; TNF-alphaR2; TNFalpha-R2; TNFBR; TNFR; TNFR II; Tnfr-1; TNFR1B; TNFR2; TNF-R2; Tnfr-2; TNF-R75; TNFR80; TNFRII; TNF-RII; TNF-R-II; TNFR-II; TNFRSF1B; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis factor receptor; tumor necrosis factor receptor 2; Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor superfamily member 1b, membrane form; tumor necrosis factor receptor superfamily, member 1B; tumor necrosis factor receptor type II; Tumor necrosis factor-binding protein 2

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
7133

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA124921

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Antigen:
Cyclin A2

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.02% Sodium azide

Gene Accession No.:
P20248

Gene Symbols:
CCNA2

Immunogen:
SDS derived male cyclin A2 fusion protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
46B11

Conjugate:
Unconjugated

Gene:
CCNA2

Gene Alias:
AA408589; Ccn1; Ccn-1; CCNA; CCNA2; ccna2.S; Cyca; CycA2; Cyclin A; cyclin A2; Cyclin A2 (Cyclin A); cyclin A2 S homeolog; Cyclin A-3; cyclin-A; Cyclin-A2; XELAEV_18009326mg

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
890

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA124926

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Antigen:
RAD51D

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O75771

Gene Symbols:
RAD51D

Immunogen:
Recombinant, full length protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Hamster, Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
Rad51D 5A8/4

Conjugate:
Unconjugated

Gene:
RAD51D

Gene Alias:
BROVCA4; DNA repair protein RAD51 homolog 4; DNA repair protein RAD51-like 4; HsTRAD; R51H3; RAD51 homolog D; RAD51 paralog D; Rad51d; RAD51L3; RAD51-like 3; RAD51-like protein 3; recombination repair protein; TRAD

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100766176, 5892

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid