PIMA125458

HDAC8 Monoclonal Antibody (HDAC8-48), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA125458-Each-of-1 In Stock ₹ 56,897.40

PIMA125458 - Each of 1

₹ 56,897.40

In Stock

Quantity

1

Base Price: ₹ 56,897.40

GST (18%): ₹ 10,241.532

Total Price: ₹ 67,138.932

Antigen

HDAC8

Classification

Monoclonal

Concentration

2.4 mg/mL

Formulation

0.01M PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

Q9BY41

Gene Symbols

HDAC8

Immunogen

Recombinant, full length human protein.

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Western Blot

Clone

HDAC8-48

Conjugate

Unconjugated

Gene

HDAC8

Gene Alias

2610007D20Rik; CDA07; CDLS5; HD8; Hdac8; HDACL1; histone deacetylase 8; histone deacetylase-like 1; MRXS6; RGD1562895; RPD3; WTS

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

55869

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • Recommended positive controls: HeLa nuclear extract
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin
  • The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones
  • Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA
  • Conversely, the deacetylation of histones is associated with transcriptional silencing
  • Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1 and the TFIID subunit TAF II p250
  • Mammalian HDAC8, isolated from human kidney, is a histone deacetylase that shares homology to other HDACs but has different tissue distribution
  • HDAC8 is localized to the nucleus and plays a role in the development of a broad range of tissues and in the etiology of cancer.

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Img

Thermo Scientific

PIMA125458

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Antigen:
HDAC8

Classification:
Monoclonal

Concentration:
2.4 mg/mL

Formulation:
0.01M PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
Q9BY41

Gene Symbols:
HDAC8

Immunogen:
Recombinant, full length human protein.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
HDAC8-48

Conjugate:
Unconjugated

Gene:
HDAC8

Gene Alias:
2610007D20Rik; CDA07; CDLS5; HD8; Hdac8; HDACL1; histone deacetylase 8; histone deacetylase-like 1; MRXS6; RGD1562895; RPD3; WTS

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
55869

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA125461

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Antigen:
H3K9acS10ph

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
0.01M PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P09588, P68431, P68433, P84228, Q71DI3

Gene Symbols:
H3C1, H3C10, H3C12, H3C14, H3C15, H3C2, H3C7, his-3, His3:CG31613, LOC107131750

Immunogen:
Synthetic, acetylated and phosphorylated (acetyl K9) & (phospho S10) peptide, conjugated to KLH, corresponding to the N-terminal residues 7-20 of huma

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Amphibian, Bovine, C. elegans, Chicken, Drosophila, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ELISA, Immunoprecipitation, Western Blot

Clone:
APH3-64

Conjugate:
Unconjugated

Gene:
H3C1

Gene Alias:
Acetyl H3; Acetyl Histone H3; B0035.7; CELE_T10C6.12; CG31613; CG31613-PA; CG33803; CG33806; CG33809; CG33812; CG33815; CG33818; CG33821; CG33824; CG33827; CG33830; CG33833; CG33836; CG33839; CG33842; CG33845; CG33848; CG33851; CG33854; CG33857; CG33860; CG33863; CG33866; Dmel\CG31613; Dmel_CG31613; F07B7.10; F07B7.3; F08G2.2; F17E9.13; F35H10.1; F45F2.4; F54E12.5; F55G1.10; H02I12.7; h3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 K9; H3 K9ac; H3 S10; H3 S10ph; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; h3.2a; H3.3 histone A; H3.3 histone B; H3.3A; H3.3b; H3.5; H3.5 histone; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-5; H3-53; H3-614; H3a; H3b; H3-B; H3C1; H3c10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3c8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3F3A protein; H3F3B; H3F3C; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; H3K9; H3K9ac; H3K9acS10p; H3Lys9acSer10p; H3Lys9acSer10ph; h3r; H3s10; H3S10ph; his-12; his-16; his-19; his-21; His3; his-3; His3:CG31613; His3:CG31613-PA; His3:CG33803; His3:CG33806; His3:CG33809; His3:CG33812; His3:CG33815; His3:CG33818; His3:CG33821; His3:CG33824; His3:CG33827; His3:CG33830; His3:CG33833; His3:CG33836; His3:CG33839; His3:CG33842; His3:CG33845; His3:CG33848; His3:CG33851; His3:CG33854; His3:CG33857; His3:CG33860; His3:CG33863; His3:CG33866; his-30; his-33; his-43; his-47; his-51; his-53; his-57; his-61; his-65; his-68; his-7; Hist1; Hist1h3a; HIST1H3B; Hist1h3c; HIST1H3D; Hist1h3e; HIST1H3F; Hist1h3g; hist1h3g.L; Hist1h3h; HIST1H3I; HIST1H3J; hist2h3; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; histone 1, H3a; histone 1, H3b; histone 1, H3f; histone 1, H3h; histone 2, H3a; histone 2, H3c; histone 2, H3c2; histone 2, H3ca2; Histone 3; histone cluster 1, H3a; histone cluster 1, H3b; histone cluster 1, H3f; histone cluster 1, H3g protein L homeolog; histone cluster 1, H3h; histone cluster 2, H3a; histone cluster 2, H3c; histone cluster 2, H3c2; histone cluster 2, H3c2, pseudogene; histone gene complex 1; Histone H2A; Histone H3; Histone H3 K9; Histone H3 K9ac; Histone H3 S10; Histone H3 S10ph; histone H3.1; Histone H3.2; histone H3.3; Histone H3.3C; histone H3.3C-like; Histone H3.5; histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; histone H3/l; Histone H3/m; histone H3/o; Histone H3K9; Histone H3K9ac; Histone H3K9acS10ph; histone H3-like; Histone H3S10; Histone H3S10ph; histone variant H3.5; K06C4.11; K06C4.3; M32461; phospho Histone 3; phospho Histone H3; Phospho-Acetyl-H3 S10 K9; Phospho-Acetyl-H3 Ser10 Lys9; Phospho-Acetyl-Histone H3 S10 K9; Phospho-Acetyl-Histone H3 Ser10 Lys9; PP781; similar to H3 histone, family 3A; T10C6.12; T23D8.6; Unknown (protein for MGC:128166); XELAEV_18028537mg; ZK131.10; ZK131.6

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
107131750, 126961, 180073, 260423, 318847, 319150, 319152, 333932, 360198, 616800, 788250, 8350, 8356, 8357, 8358, 8968, 97114

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Thermo Scientific

PIMA125470

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Antigen:
PRMT5

Classification:
Monoclonal

Concentration:
2.4 mg/mL

Formulation:
0.01M PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
A7YW45, O14744, Q8CIG8

Gene Symbols:
PRMT5

Immunogen:
Fusion of mouse myeloma cells and splenocytes from mice immunized with PRMT5 containing the C-terminal region of the Human PRMT5 (residues 315-637).

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Chicken, Hamster, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ChIP Assay, ELISA, Western Blot

Clone:
PRMT5-21

Conjugate:
Unconjugated

Gene:
PRMT5

Gene Alias:
72 kDa ICln-binding protein; EC 2.1.1.125; histone-arginine N-methyltransferase PRMT5; HMT1 hnRNP methyltransferase-like 5; HRMT1L5; hypothetical protein; I79_013398; IBP72; Jak-binding protein 1; JBP1; PRMT5; protein arginine methyltransferase 5; protein arginine N-methyltransferase 5; Protein arginine N-methyltransferase 5, N-terminally processed; protein arginine N-methyltransferase 5-like; shk1 kinase-binding protein 1 homolog; Skb1; SKB1 homolog; SKB1Hs

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
100768836, 101750306, 10419, 27374, 364382, 480242, 515594

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA125482

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Antigen:
Synaptotagmin 1

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.1mM PMSF, 50% glycerol and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P21707, P46096, P48018

Gene Symbols:
Syt1

Immunogen:
Rat brain synaptic junction protein complexes.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Mouse, Non-human Primate, Rat, Shark

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
ASV48

Conjugate:
Unconjugated

Gene:
Syt1

Gene Alias:
AW124717; DKFZp781D2042; FLJ42519; G630098F17Rik; P65; SV DKFZp781D2042; SV SYT; svp65; Syb1; synaptotagmin 1; synaptotagmin 1 L homeolog; synaptotagmin 2; synaptotagmin I; synaptotagmin I protein; synaptotagmin I variant b; Synaptotagmin II; Synaptotagmin XI; synaptotagmin-1; Synaptotagmin-2; SYT; Syt1; syt1.L; SYT2; SytI; SytII; XELAEV_18022019mg

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
20979, 25716, 281511

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid