PIMA125482

Synaptotagmin 1 Monoclonal Antibody (ASV48), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA125482-Each-of-1 In Stock ₹ 48,640.86

PIMA125482 - Each of 1

₹ 48,640.86

In Stock

Quantity

1

Base Price: ₹ 48,640.86

GST (18%): ₹ 8,755.355

Total Price: ₹ 57,396.215

Antigen

Synaptotagmin 1

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 0.1mM PMSF, 50% glycerol and 0.09% sodium azide; pH 7.2

Gene Accession No.

P21707, P46096, P48018

Gene Symbols

Syt1

Immunogen

Rat brain synaptic junction protein complexes.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Mouse, Non-human Primate, Rat, Shark

Product Type

Antibody

Isotype

IgG2b

Applications

Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone

ASV48

Conjugate

Unconjugated

Gene

Syt1

Gene Alias

AW124717; DKFZp781D2042; FLJ42519; G630098F17Rik; P65; SV DKFZp781D2042; SV SYT; svp65; Syb1; synaptotagmin 1; synaptotagmin 1 L homeolog; synaptotagmin 2; synaptotagmin I; synaptotagmin I protein; synaptotagmin I variant b; Synaptotagmin II; Synaptotagmin XI; synaptotagmin-1; Synaptotagmin-2; SYT; Syt1; syt1.L; SYT2; SytI; SytII; XELAEV_18022019mg

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

20979, 25716, 281511

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • Possible positive controls for this product are rat brain tissue extract
  • Synaptotagmin 1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release
  • Studies indicate that synaptotagmin’s Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane
  • It has been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size
  • Synaptotagmin 1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse
  • Further, Synaptotagmin 1 binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone
  • A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has been reported
  • Synaptotagmin 1 can also bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2
  • Diseases associated with the dysfunction of Synaptotagmin 1 include food-borne botulism and infant botulism.

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Img

Thermo Scientific

PIMA125482

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Antigen:
Synaptotagmin 1

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.1mM PMSF, 50% glycerol and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P21707, P46096, P48018

Gene Symbols:
Syt1

Immunogen:
Rat brain synaptic junction protein complexes.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Mouse, Non-human Primate, Rat, Shark

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
ASV48

Conjugate:
Unconjugated

Gene:
Syt1

Gene Alias:
AW124717; DKFZp781D2042; FLJ42519; G630098F17Rik; P65; SV DKFZp781D2042; SV SYT; svp65; Syb1; synaptotagmin 1; synaptotagmin 1 L homeolog; synaptotagmin 2; synaptotagmin I; synaptotagmin I protein; synaptotagmin I variant b; Synaptotagmin II; Synaptotagmin XI; synaptotagmin-1; Synaptotagmin-2; SYT; Syt1; syt1.L; SYT2; SytI; SytII; XELAEV_18022019mg

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
20979, 25716, 281511

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA125493

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Antigen:
beta Amyloid

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and no preservative; pH 7.2

Gene Accession No.:
P05067, P12023

Gene Symbols:
APP

Immunogen:
Synthetic peptide corresponding to residues 1-16 of beta Amyloid.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
2C8

Conjugate:
Unconjugated

Gene:
APP

Gene Alias:
A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; amyloid precursor protein variant 1; amyloid precursor protein variant 2; Amyloid β; amyloid-beta A4 protein; amyloid-beta A4 protein; amyloid beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta amyloid protein; beta amyloid protein precursor; beta-amyloid peptide; be

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11820, 351

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA125510

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Antigen:
Cytohesin 2

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
0.01M PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P63035, Q99418

Gene Symbols:
CYTH2

Immunogen:
Recombinant, full length human protein.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
CYT2-21

Conjugate:
Unconjugated

Gene:
CYTH2

Gene Alias:
ARF exchange factor; ARF nucleotide binding site opener; ARF nucleotide-binding site opener; ARNO; CLM2; CTC-273B12.8; CTS18; CTS18.1; Cyth2; cytohesin 2; cytohesin-2; mSec7-2; PH, SEC7 and coiled-coil domain-containing protein 2; pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2); pleckstrin homology, Sec7 and coiled-coil domains 2; pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2); Protein ARNO; PSCD2; PSCD2L; Sec7; SEC7 homolog B; Sec7b; SEC7L; Sec7p-L; Sec7p-like

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
116692, 9266

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA125525

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Antigen:
IRF4

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
tissue culture supernatant with 0.09% sodium azide

Gene Accession No.:
Q15306

Gene Symbols:
IRF4

Immunogen:
Recombinant MUM1 protein.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
MUM1p

Conjugate:
Unconjugated

Gene:
IRF4

Gene Alias:
AI385587; interferon regulatory factor 4; Irf4; IRF-4; LSIRF; Lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; SHEP8; Spip; Transcriptional activator PIP

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
3662

Content And Storage:
4° C, do not freeze

Form:
Liquid