PIMA125835
Perforin Monoclonal Antibody (CE2.10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA125835-Each-of-1 | In Stock | ₹ 48,298.62 |
PIMA125835 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,298.62
GST (18%): ₹ 8,693.752
Total Price: ₹ 56,992.372
Antigen
Perforin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P10820, P14222
Gene Symbols
PRF1
Immunogen
Recombinant fragment corresponding to residues 98-534 of mouse Perforin.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2a
Applications
Immunoprecipitation, Western Blot
Clone
CE2.10
Conjugate
Unconjugated
Gene
PRF1
Gene Alias
Cyta; Cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; lymphocyte pore-forming protein; OMAK; OTTHUMP00000019759; P1; perforin 1; perforin 1 (pore forming protein); Perforin1; perforin-1; Pfn; PFN1; Pfp; PGFL; PIGF; PIGF-2; PLGF; pore forming protein; pore-forming protein; PRF1; Prf-1; PRF1 (pore forming protein 1); RATCYTA; RP11-710A11.3
Host Species
Mouse
Purification Method
Size-exclusion - Gel filtration
Regulatory Status
RUO
Gene ID (Entrez)
18646, 5551
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA1-25835 detects a band ∽C66 kDa from the mouse T cell clone B6.1 (pos
- control)
- This antibody does not detect human perforin by western blot
- Perforin is one of the major cytolytic proteins of cytolytic granules
- Perforin is a cytolytic mediator and is stored in and released by cytoplasmic granules
- Moreover, perforin is involved in immune defense against tumors and virus infections as mediated by cytotoxic lymphocytes
- Perforin is a 555 amino acid protein with a 21 amino acid signal peptide, and has a molecular weight of 70 to 75 kD
- Perforin is a pore forming protein with a mechanism of transmembrane channel formation similar to C9, and homology between perforin and C9 have been demonstrated
- Studies show that perforin is expressed only in killer cell lines and not in helper T lymphocytes or other tumor cells tested
- Perforin is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis
- Defects in the perforin gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood
- Alternative splicing results in multiple transcript variants of perforin.
Compare Similar Items
Show Difference
Antigen: Perforin
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P10820, P14222
Gene Symbols: PRF1
Immunogen: Recombinant fragment corresponding to residues 98-534 of mouse Perforin.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2a
Applications: Immunoprecipitation, Western Blot
Clone: CE2.10
Conjugate: Unconjugated
Gene: PRF1
Gene Alias: Cyta; Cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; lymphocyte pore-forming protein; OMAK; OTTHUMP00000019759; P1; perforin 1; perforin 1 (pore forming protein); Perforin1; perforin-1; Pfn; PFN1; Pfp; PGFL; PIGF; PIGF-2; PLGF; pore forming protein; pore-forming protein; PRF1; Prf-1; PRF1 (pore forming protein 1); RATCYTA; RP11-710A11.3
Host Species: Mouse
Purification Method: Size-exclusion - Gel filtration
Regulatory Status: RUO
Gene ID (Entrez): 18646, 5551
Content And Storage: 4° C
Form: Liquid
Antigen:
Perforin
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P10820, P14222
Gene Symbols:
PRF1
Immunogen:
Recombinant fragment corresponding to residues 98-534 of mouse Perforin.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunoprecipitation, Western Blot
Clone:
CE2.10
Conjugate:
Unconjugated
Gene:
PRF1
Gene Alias:
Cyta; Cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; lymphocyte pore-forming protein; OMAK; OTTHUMP00000019759; P1; perforin 1; perforin 1 (pore forming protein); Perforin1; perforin-1; Pfn; PFN1; Pfp; PGFL; PIGF; PIGF-2; PLGF; pore forming protein; pore-forming protein; PRF1; Prf-1; PRF1 (pore forming protein 1); RATCYTA; RP11-710A11.3
Host Species:
Mouse
Purification Method:
Size-exclusion - Gel filtration
Regulatory Status:
RUO
Gene ID (Entrez):
18646, 5551
Content And Storage:
4° C
Form:
Liquid
Antigen: Bcl-rambo
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q9BXK5
Gene Symbols: BCL2L13
Immunogen: Recombinant fragment corresponding to the C-terminal residues 224-459 of human Bcl rambo, fused at the N-terminus to a tag.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: Rocky-2
Conjugate: Unconjugated
Gene: BCL2L13
Gene Alias: BCL2 like 13; BCL2L13; Bcl2-L-13; BCL2-like 13 (apoptosis facilitator); bcl-2-like protein 13; Bcl-rambo; CD003; E430016C20Rik; MIL1; Mil-1; mitochondria located 1 homolog; protein Mil1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 23786
Content And Storage: 4° C
Form: Liquid
Antigen:
Bcl-rambo
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q9BXK5
Gene Symbols:
BCL2L13
Immunogen:
Recombinant fragment corresponding to the C-terminal residues 224-459 of human Bcl rambo, fused at the N-terminus to a tag.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
Rocky-2
Conjugate:
Unconjugated
Gene:
BCL2L13
Gene Alias:
BCL2 like 13; BCL2L13; Bcl2-L-13; BCL2-like 13 (apoptosis facilitator); bcl-2-like protein 13; Bcl-rambo; CD003; E430016C20Rik; MIL1; Mil-1; mitochondria located 1 homolog; protein Mil1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
23786
Content And Storage:
4° C
Form:
Liquid
Antigen: CD15
Classification: Monoclonal
Concentration: __
Formulation: tissue culture supernatant with 0.09% sodium azide
Gene Accession No.: P22083, Q11127
Gene Symbols: FUT4
Immunogen: U937 histiocytic cell line.
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgM
Applications: Immunohistochemistry (Paraffin)
Clone: MMA
Conjugate: Unconjugated
Gene: FUT4
Gene Alias: FUTIV, Lewis X, SSEA-1
Host Species: Mouse
Purification Method: IgM
Regulatory Status: RUO
Gene ID (Entrez): 14345, 2526
Content And Storage: 4° C, do not freeze
Form: Liquid
Antigen:
CD15
Classification:
Monoclonal
Concentration:
__
Formulation:
tissue culture supernatant with 0.09% sodium azide
Gene Accession No.:
P22083, Q11127
Gene Symbols:
FUT4
Immunogen:
U937 histiocytic cell line.
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgM
Applications:
Immunohistochemistry (Paraffin)
Clone:
MMA
Conjugate:
Unconjugated
Gene:
FUT4
Gene Alias:
FUTIV, Lewis X, SSEA-1
Host Species:
Mouse
Purification Method:
IgM
Regulatory Status:
RUO
Gene ID (Entrez):
14345, 2526
Content And Storage:
4° C, do not freeze
Form:
Liquid
Antigen: MCP-1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.2
Gene Accession No.: P13500
Gene Symbols: Ccl2
Immunogen: Recombinant, full length human protein.
Quantity: 250 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Inhibition Assays, Neutralization, Western Blot
Clone: S14
Conjugate: Unconjugated
Gene: Ccl2
Gene Alias: Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 6347
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MCP-1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.2
Gene Accession No.:
P13500
Gene Symbols:
Ccl2
Immunogen:
Recombinant, full length human protein.
Quantity:
250 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Inhibition Assays, Neutralization, Western Blot
Clone:
S14
Conjugate:
Unconjugated
Gene:
Ccl2
Gene Alias:
Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
6347
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid