PIMA125847

Bcl-rambo Monoclonal Antibody (Rocky-2), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA125847-Each-of-1 In Stock ₹ 48,127.50

PIMA125847 - Each of 1

₹ 48,127.50

In Stock

Quantity

1

Base Price: ₹ 48,127.50

GST (18%): ₹ 8,662.95

Total Price: ₹ 56,790.45

Antigen

Bcl-rambo

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q9BXK5

Gene Symbols

BCL2L13

Immunogen

Recombinant fragment corresponding to the C-terminal residues 224-459 of human Bcl rambo, fused at the N-terminus to a tag.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

Rocky-2

Conjugate

Unconjugated

Gene

BCL2L13

Gene Alias

BCL2 like 13; BCL2L13; Bcl2-L-13; BCL2-like 13 (apoptosis facilitator); bcl-2-like protein 13; Bcl-rambo; CD003; E430016C20Rik; MIL1; Mil-1; mitochondria located 1 homolog; protein Mil1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

23786

Content And Storage

4° C

Form

Liquid

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Description

  • MA1-25847 detects Bcl rambo from human samples
  • Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells
  • Disruption of this process has been implicated in a variety of diseases such as cancer
  • Members of the Bcl-2 family are known to be critical regulators of this process
  • These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains
  • A novel, widely expressed member termed Bcl-rambo was recently identified
  • This protein is localized to mitochondria in mammalian cells and its overexpression induces apoptosis which could be blocked by co-expression of inhibitor of apoptosis proteins (IAPs) such as XIAP, cIAP1, and cIAP2
  • Bcl-rambo shows overall homology to the anti-apoptotic members containing BH motifs, but unlike Bcl-2, the C-terminal membrane anchor of Bcl-rambo is preceded by a unique 250 amino acid insertion
  • This region by itself can induce apoptosis more efficiently than the Bcl-2 homology regions, suggesting that Bcl-rambo may be important other pro-apoptotic pathways.

Compare Similar Items

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Img

Thermo Scientific

PIMA125847

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Antigen:
Bcl-rambo

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9BXK5

Gene Symbols:
BCL2L13

Immunogen:
Recombinant fragment corresponding to the C-terminal residues 224-459 of human Bcl rambo, fused at the N-terminus to a tag.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
Rocky-2

Conjugate:
Unconjugated

Gene:
BCL2L13

Gene Alias:
BCL2 like 13; BCL2L13; Bcl2-L-13; BCL2-like 13 (apoptosis facilitator); bcl-2-like protein 13; Bcl-rambo; CD003; E430016C20Rik; MIL1; Mil-1; mitochondria located 1 homolog; protein Mil1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
23786

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA125911

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Antigen:
CD15

Classification:
Monoclonal

Concentration:
__

Formulation:
tissue culture supernatant with 0.09% sodium azide

Gene Accession No.:
P22083, Q11127

Gene Symbols:
FUT4

Immunogen:
U937 histiocytic cell line.

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgM

Applications:
Immunohistochemistry (Paraffin)

Clone:
MMA

Conjugate:
Unconjugated

Gene:
FUT4

Gene Alias:
FUTIV, Lewis X, SSEA-1

Host Species:
Mouse

Purification Method:
IgM

Regulatory Status:
RUO

Gene ID (Entrez):
14345, 2526

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA126057

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Antigen:
MCP-1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
P13500

Gene Symbols:
Ccl2

Immunogen:
Recombinant, full length human protein.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Inhibition Assays, Neutralization, Western Blot

Clone:
S14

Conjugate:
Unconjugated

Gene:
Ccl2

Gene Alias:
Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6347

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA126062

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Antigen:
SHP-1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
0.01M PBS with no preservative; pH 7.2

Gene Accession No.:
P29350

Gene Symbols:
PTPN6

Immunogen:
Recombinant, full length human protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
PTY11

Conjugate:
Unconjugated

Gene:
PTPN6

Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5777

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid