PIMA146069
Phospho-ATM (Ser1981) Monoclonal Antibody (10H11.E12), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA146069-Each-of-1 | In Stock | ₹ 48,726.42 |
PIMA146069 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,726.42
GST (18%): ₹ 8,770.756
Total Price: ₹ 57,497.176
Antigen
Phospho-ATM (Ser1981)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
Q13315, Q62388
Gene Symbols
ATM
Immunogen
A synthetic peptide with a phosphorylated serine (1981).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1 κ
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
10H11.E12
Conjugate
Unconjugated
Gene
ATM
Gene Alias
AI256621; AT mutated; A-T mutated; A-T mutated homolog; AT mutated protein; AT1; ATA; Ataxia t; Ataxia telangiectasia gene mutated in human beings; ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; ATC; ATD; ATDC; ATE; Atm; ATM (phospho S1981); ATM (pS1981); ATM (pSer1981); ATM phospho S1981; ATM phospho Ser1981; ATM serine/threonine kinase; C030026E19Rik; DKFZp781A0353; EC 2.7.1.37; MGC74674; phospho ATM; phospho S1981 ATM; serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
11920, 300711, 472
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- This antibody does not react with canine samples
- Suggested positive control: Irradiated normal human fibroblasts
- No reactivity against un-irradiated cell extracts
- Ataxia-telangiectasia Mutated (ATM) is a protein that belongs to the PI3/PI4 kinase family
- Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by progressive neurologic degeneration, immunologic deficiency, and an increased risk of lymphoid cancer
- The ATM gene codes for a protein belonging to the phosphoinositide 3-kinase (PI3K) superfamily
- ATM phosphorylates proteins instead of lipid and has many downstream targets that act as cell-cycle regulators including: P53, Mdm2, BRCA1, and SMC1
- The ATM protein is responsible for repairing double-stranded DNA breaks that occur because of ionizing radiation and other mutagens
- The ATM’s C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases)
- Studies have shown that ATM becomes autophosphorylated and upregulated by exposure to ionizing radiation
- AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction
- Further, DNA damage caused by ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair
- Studies have linked ATM to apoptosis along with Nbs1 and Chk2 in the E2F1 pathway.
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Antigen: Phospho-ATM (Ser1981)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q13315, Q62388
Gene Symbols: ATM
Immunogen: A synthetic peptide with a phosphorylated serine (1981).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 10H11.E12
Conjugate: Unconjugated
Gene: ATM
Gene Alias: AI256621; AT mutated; A-T mutated; A-T mutated homolog; AT mutated protein; AT1; ATA; Ataxia t; Ataxia telangiectasia gene mutated in human beings; ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; ATC; ATD; ATDC; ATE; Atm; ATM (phospho S1981); ATM (pS1981); ATM (pSer1981); ATM phospho S1981; ATM phospho Ser1981; ATM serine/threonine kinase; C030026E19Rik; DKFZp781A0353; EC 2.7.1.37; MGC74674; phospho ATM; phospho S1981 ATM; serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 11920, 300711, 472
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Phospho-ATM (Ser1981)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q13315, Q62388
Gene Symbols:
ATM
Immunogen:
A synthetic peptide with a phosphorylated serine (1981).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
10H11.E12
Conjugate:
Unconjugated
Gene:
ATM
Gene Alias:
AI256621; AT mutated; A-T mutated; A-T mutated homolog; AT mutated protein; AT1; ATA; Ataxia t; Ataxia telangiectasia gene mutated in human beings; ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; ATC; ATD; ATDC; ATE; Atm; ATM (phospho S1981); ATM (pS1981); ATM (pSer1981); ATM phospho S1981; ATM phospho Ser1981; ATM serine/threonine kinase; C030026E19Rik; DKFZp781A0353; EC 2.7.1.37; MGC74674; phospho ATM; phospho S1981 ATM; serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
11920, 300711, 472
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Apolipoprotein A5
Classification: Monoclonal
Concentration: 1.2 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: Q6Q788
Gene Symbols: APOA5
Immunogen: Ni-NTA purified full-length recombinant human Apolipoprotein A5 expressed in E Coli strain BL21 (DE3)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: ELISA, Flow Cytometry, Immunocytochemistry
Clone: 4H8H8E2
Conjugate: Unconjugated
Gene: APOA5
Gene Alias: 1300007O05Rik; APOA5; Apoav; apo-AV; apoA-V; apolipoprotein A5; apolipoprotein AV; Apolipoprotein A-V; apolipoprotein A-V precursor variant 3; apolipoprotein A-V; apolipoprotein A5; FLJ97995; MGC126836; MGC126838; Rap3; Regeneration-associated protein 3; UNQ411/PRO773
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 116519
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Apolipoprotein A5
Classification:
Monoclonal
Concentration:
1.2 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
Q6Q788
Gene Symbols:
APOA5
Immunogen:
Ni-NTA purified full-length recombinant human Apolipoprotein A5 expressed in E Coli strain BL21 (DE3)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
ELISA, Flow Cytometry, Immunocytochemistry
Clone:
4H8H8E2
Conjugate:
Unconjugated
Gene:
APOA5
Gene Alias:
1300007O05Rik; APOA5; Apoav; apo-AV; apoA-V; apolipoprotein A5; apolipoprotein AV; Apolipoprotein A-V; apolipoprotein A-V precursor variant 3; apolipoprotein A-V; apolipoprotein A5; FLJ97995; MGC126836; MGC126838; Rap3; Regeneration-associated protein 3; UNQ411/PRO773
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
116519
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: EpCAM
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P16422
Gene Symbols: EPCAM
Immunogen: LoVo cell line preparation (Human).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: AUA1
Conjugate: Unconjugated
Gene: EPCAM
Gene Alias: adenocarcinoma-associated antigen; CD326; cell surface glycoprotein Trop-1; DIAR5; EGP; EGP-2; EGP314; EGP40; EPCAM; Ep-CAM; EpCAM1; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733-2; gp40; hEGP314; HNPCC8; human epithelial glycoprotein-2; KS 1/4 antigen; KS1/4; KSA; Ly74; lymphocyte antigen 74; M1S2; M4S1; major gastrointestinal tumor-associated protein GA733-2; mEGP314; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; panepithelial glycoprotein 314; protein 289A; Protein D5.7A; Tacsd1; Tacstd1; TROP1; Trop-1 protein; Tumor-associated calcium signal transducer 1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 4072
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
EpCAM
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
P16422
Gene Symbols:
EPCAM
Immunogen:
LoVo cell line preparation (Human).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
AUA1
Conjugate:
Unconjugated
Gene:
EPCAM
Gene Alias:
adenocarcinoma-associated antigen; CD326; cell surface glycoprotein Trop-1; DIAR5; EGP; EGP-2; EGP314; EGP40; EPCAM; Ep-CAM; EpCAM1; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733-2; gp40; hEGP314; HNPCC8; human epithelial glycoprotein-2; KS 1/4 antigen; KS1/4; KSA; Ly74; lymphocyte antigen 74; M1S2; M4S1; major gastrointestinal tumor-associated protein GA733-2; mEGP314; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; panepithelial glycoprotein 314; protein 289A; Protein D5.7A; Tacsd1; Tacstd1; TROP1; Trop-1 protein; Tumor-associated calcium signal transducer 1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
4072
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: HLA-DQw1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P01920
Gene Symbols: HLA-DQB1
Immunogen: Preparation of human Bristol 8 glycoprotein from the Bristol 8 B lymphoblastoid cell line.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone: Genox 3.53
Conjugate: Unconjugated
Gene: HLA-DQB1
Gene Alias: CELIAC1; HLA class II antigen; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA-DQB; HLA-DQB1; HLA-DRB1; IDDM1; lymphocyte antigen; major histocompatibility complex, class II, DQ beta 1; MHC class II antigen DQB1; MHC class II antigen HLA-DQ-beta-1; MHC class II DQ beta chain; MHC class II HLA-DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta
Host Species: Mouse
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 3119
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
HLA-DQw1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P01920
Gene Symbols:
HLA-DQB1
Immunogen:
Preparation of human Bristol 8 glycoprotein from the Bristol 8 B lymphoblastoid cell line.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone:
Genox 3.53
Conjugate:
Unconjugated
Gene:
HLA-DQB1
Gene Alias:
CELIAC1; HLA class II antigen; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA-DQB; HLA-DQB1; HLA-DRB1; IDDM1; lymphocyte antigen; major histocompatibility complex, class II, DQ beta 1; MHC class II antigen DQB1; MHC class II antigen HLA-DQ-beta-1; MHC class II DQ beta chain; MHC class II HLA-DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta
Host Species:
Mouse
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
3119
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid