Toxoplasma gondii P30 Monoclonal Antibody (J26A), FITC, Invitrogen™

Description

• The MA1-7436 antibody reacts with Toxoplasma gondii in bacterial and infected tissue samples
• MA1-7436 has been successfully used in ELISA, Immunofluorescence and Western blot applications
• The MA1-7436 antibody was raised against Whole organism preparation
• Toxoplasma is a crescent shaped sporozoan that lives as intracellular parasite in various tissues of vertebrates and completes its life cycle in a single host
• It is transmitted via raw/undercooked meat, contaminated soil, or by direct contact
• Infection due to Toxoplasma gondii usually occurs in pregnant women where a variable degree of immunosuppression may exist or in patients receiving immunosuppressive drug therapy following organ transplant
• Toxoplasma infects tissue of the GI tract where an active infection is accompanied by fever and enlargement of the spleen
• Symptoms of toxoplasmosis are generally mild but severe infection of lymph nodes may occur
• Congenital toxoplasmosis, in which the maternal infection is transmitted during pregnancy, can produce blindness or mental retardation in the newborn
• Toxoplasma gondii infections in humans are widespread but vary greatly by region
• The organism enters the intestinal epithelium and can spread to other host tissues
• In healthy individuals the infection is usually asymptomatic
• However, for individuals with compromised immune systems, a Toxoplasma infection can cause serious health problems.