pan T cells Monoclonal Antibody (OX-52), FITC, Invitrogen™

Description

• Anti-rat pan T lymphocyte monoclonal antibody immunoprecipitates a two chain structure (95, 120 kDa) largely restricted to T lymphocytes and thymocytes
• Applications therefore include the identification of T lymphocyte lineage cells in suspension and tissue
• Has previously been used to stain T cell areas of the spleen, lymph nodes and Peyer's patch
• In the thymus, labels all thymocytes, however medullary cells are more strongly positive than cortical cells
• The antibody does not label such non-lymphoid tissues such as brain, kidney, liver and skin
• This antibody stains approximately 1.0 % of bone marrow cells, and 56 % thoracic duct lymphocytes
• Weak staining occurs with 50 % dendritic cells from thoracic duct of mesenteric lymphadenectomized rats
• The antigen recognized by this antibody is not expressed on granulocytes or macrophages
• The function of the antigen recognized by this antibody has not, as yet, been associated with any particular function of T cells
• The antibody does not inhibit the allogeneic mixed leukocyte response, nor does it inhibit T cytotoxic effector cell function
• This clone works in flow cytometry, Immunoprecipitation and with frozen sections
• pan T cells Monoclonal antibody specifically detects pan T cells in Rat samples
• It is validated for Flow Cytometry.