PIMA180900

CD8 Monoclonal Antibody (38.65), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA180900-Each-of-1 In Stock ₹ 69,474.72

PIMA180900 - Each of 1

₹ 69,474.72

In Stock

Quantity

1

Base Price: ₹ 69,474.72

GST (18%): ₹ 12,505.45

Total Price: ₹ 81,980.17

Antigen

CD8

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 1% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

P31783

Gene Symbols

Cd8a, CD8B

Immunogen

Ovine efferent lymphocytes.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Goat, Ovine

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry

Clone

38.65

Conjugate

FITC

Gene

Cd8a

Gene Alias

BB154331; CD8; CD8 alpha; CD8 alpha chain; CD8 alpha chain precursor; CD8 antigen; CD8 antigen 32 kDa chain; CD8 antigen 37 kDa chain; CD8 antigen alpha polypeptide; CD8 antigen alpha protein; CD8 antigen alpha protein precursor; CD8 antigen alpha-chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide (p32); CD8 antigen, alpha-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8 beta-2; CD8a; CD8A antigen alpha; CD8a molecule; CD8A; T-cell surface glycoprotein; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; Cd8b1; CD8beta; CD8BP; fCD8; LEU2; Leu-2; Leu2 T-lymphocyte antigen; leu-2a; Ly-2; LY3; Ly-3; Ly-35; Ly-B; Ly-C; Lymphocyte antigen 3; Lyt2; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); Lyt3; Lyt-3; MAL; membrane glycoprotein; membrane protein; OKT8 T-cell antigen; OX-8 membrane antigen; p32; P37; RHACD8-4; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T8 T-cell antigen; T-cell antigen Leu2; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-2; T-cell surface glycoprotein Lyt-3; T-cell surface molecule; T-lymphocyte differentiation antigen T8/Leu-2; type I transmembrane glycoprotein

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

101103464, 101103712, 102184733, 102185010, 281060, 508633

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form

Liquid

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Description

  • For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
  • Mouse anti Sheep CD8 antibody, clone 38.65 recognizes the ovine CD8 cell surface antigen, which is expressed by the cytotoxic/suppressor subset of T lymphocytes
  • Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation
  • CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer of CD8alpha and CD8beta, where it functions as a co-receptor, along with T cell receptor (TCR), for major histocompatibilty complex class I (MHC-I) molecules; whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules
  • CD8 exists on the cell surface, where the CD8alpha chain is essential for binding to MHC-I
  • CD8 is also expressed on a subset of T cells, NK cells, monocytes and dendritic cells as disulfide-linked homodimers of CD8alpha
  • Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine production, motility and cytotoxic T lymphocyte (CTL) activation
  • Once activated, CTLs play a crucial role in the clearance of pathogens and tumor cells
  • Differentiation of naive CD8+ T cells into CTLs is strongly enhanced by IL-2, IL-12 and TGF-beta1.

Compare Similar Items

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Img

Thermo Scientific

PIMA180900

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Antigen:
CD8

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P31783

Gene Symbols:
Cd8a, CD8B

Immunogen:
Ovine efferent lymphocytes.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Goat, Ovine

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
38.65

Conjugate:
FITC

Gene:
Cd8a

Gene Alias:
BB154331; CD8; CD8 alpha; CD8 alpha chain; CD8 alpha chain precursor; CD8 antigen; CD8 antigen 32 kDa chain; CD8 antigen 37 kDa chain; CD8 antigen alpha polypeptide; CD8 antigen alpha protein; CD8 antigen alpha protein precursor; CD8 antigen alpha-chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide; CD8 antigen, alpha polypeptide (p32); CD8 antigen, alpha-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8 beta-2; CD8a; CD8A antigen alpha; CD8a molecule; CD8A; T-cell surface glycoprotein; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; Cd8b1; CD8beta; CD8BP; fCD8; LEU2; Leu-2; Leu2 T-lymphocyte antigen; leu-2a; Ly-2; LY3; Ly-3; Ly-35; Ly-B; Ly-C; Lymphocyte antigen 3; Lyt2; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); Lyt3; Lyt-3; MAL; membrane glycoprotein; membrane protein; OKT8 T-cell antigen; OX-8 membrane antigen; p32; P37; RHACD8-4; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T8 T-cell antigen; T-cell antigen Leu2; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-2; T-cell surface glycoprotein Lyt-3; T-cell surface molecule; T-lymphocyte differentiation antigen T8/Leu-2; type I transmembrane glycoprotein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
101103464, 101103712, 102184733, 102185010, 281060, 508633

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form:
Liquid

Img

Thermo Scientific

PIMA180907

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Antigen:
HLA-ABC

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.:
P01889, P04439, P10321

Gene Symbols:
HLA-A, HLA-B, HLA-C, LOC100515902

Immunogen:
Purified H-2Kb and H-2Db MHC-I molecules.

Quantity:
250 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Guinea Pig, Hamster, Human, Mouse, Ovine, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunoprecipitation

Clone:
2G5

Conjugate:
Unconjugated

Gene:
HLA-C

Gene Alias:
A29 protein, alpha chain of MHC class II, antigen presenting molecule, AS, Aw-33, Aw-74, B-4901, B-5001, Bw-47, Bw-50, class I MHC, HLA-B antigen, D6S204, epididymis secretory protein Li 83, H-2K, H2-K, H-2K(d), HEL-S-83, histocompatibility antigen, HLA A, HLA -B, HLA B-40011, HLA B44, HLA C, HLA class I antigen, HLA class I antigen HLA-B, HLA class I histocompatibility antigen C alpha chain, HLA class I histocompatibility antigen Cw-1 alpha chain, HLA class I histocompatibility antigen, A alpha chain, HLA class I histocompatibility antigen, A-1 alpha chain, HLA class I histocompatibility antigen, A-11 alpha chain-like, HLA class I histocompatibility antigen, A-30 alpha chain, HLA class I histocompatibility antigen, A-33 alpha chain, HLA class I histocompatibility antigen, A-74 alpha chain, HLA class I histocompatibility antigen, B alpha chain, HLA class I histocompatibility antigen, B-47 alpha chain, HLA class I histocompatibility antigen, B-50 alpha chain, HLA class I histocompatibility antigen, B-82 alpha chain, HLA class I histocompatibility antigen, C alpha chain, HLA class I histocompatibility antigen, Cw-1 alpha chain, HLA class I histocompatibility antigen, Cw-15 alpha chain, HLA class I histocompatibility antigen, Cw-18 alpha chain, HLA locus, HLA molecule, HLAA, HLA-A, HLA-A locus alpha 2 domain, HLA-A null, HLA-A11, HLA-A33, HLA-Aw33.1, HLAB, HLA-B, HLA-B 1502, HLA-B alpha chain, HLA-B alpha chain (B*2706), HLA-B alpha chain (B*5002), HLA-B alpha-chain, HLA-B*45ZJ, HLA-B15, HLA-B35, HLA-B35 antigen, HLA-B-3506, HLA-B39, HLA-B-3905, HLA-B49, HLA-B50, HLA-B55, HLA-B-5502, HLA-B-5602, HLA-B59, HLA-B61, HLA-Bw50 antigen, HLAC, HLA-C, HLA-C alpha chain, HLA-C alpha chain (HLA-Cw*15v), HLA-C alpha chain for Cw*18GB, HLA-C alpha-chain, HLA-C antigen, HLA-Cw, HLA-Cw*04GB, HLA-Cw*1702, HLA-Cw*18GB, HLA-Cw-1503, HLA-DQB1, HLA-DRB1, HLA-JY3, HLC-C, Human leukocyte antigen A, Human leukocyte antigen C, human leukocyte antigen-C alpha chain, hypothetical protein, lecocyte antigen B, leucocyte antigen A, Leukocyte Antigen, leukocyte antigen C, leukocyte antigen class I-A, leukocyte antigen class I-B, Leukoocyte Antigen, LOC100515902, LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-11 alpha chain-like, lymphocyte antigen, major histocompatability complex B antigen, major histocompatibility antigen HLA-C, major histocompatibility complex, class I, A, major histocompatibility complex, class I, B, major histocompatibility complex, class I, C, MCH class I antigen, MGC184092, MGC7052, MHC, MHC 1, MHC antigen, MHC clas I antigen, MHC Class 1, MHC class 1 antigen, MHC class I, MHC class I alpha chain, MHC class I anitgen, MHC class I anti, MHC Class I antigen, MHC class I antigen A*30, MHC class I antigen A*33, MHC class I antigen A*74, MHC class I antigen B*47, MHC class I antigen B*50, MHC class I antigen B*82, MHC class I antigen Cw*15, MHC class I antigen Cw*18, MHC class I antigen GN00104, MHC class I antigen heavy chain, MHC class I antigen heavy chain HLA-C, MHC class I antigen HLA-A heavy chain, MHC class I antigen HLA-A33, MHC class I antigen HLA-B alpha chain, MHC class I antigen HLA-B heavy chain, MHC class I antigen null protein, MHC class I antigen SHCHA, MHC class I antigene, MHC class I histocompatibility antigen, MHC class I human leukocyte antigen, MHC class I molecule, MHC class I protein, MHC class II antigen, MHC class l antigen, MHC classI antigen, MHC HLA-ABC, MHC HLA-B cell surface glycoprotein, MHC HLA-B transmembrane glycoprotein, MHC HLA-B27d, MHC HLA-B27-HS, MHC HLA-B39N, MHC I HLA, MHC1, PSORS1, SPDA1, surface antigen, truncated class I antigen, truncated MHC class I antigen

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100515902, 3105, 3106, 3107

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA180926

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Antigen:
CD40

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with <0.1% sodium azide

Gene Accession No.:
P25942, Q7YRL5

Gene Symbols:
CD40

Immunogen:
CD40 Ig(Fc) fusion protein containing the EC region of human CD40 and Fc region of human IgG

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
LOB7/6

Conjugate:
Unconjugated

Gene:
CD40

Gene Alias:
AI326936; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD antigen CD40; Cd40; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5); CD40 antigen, TNF receptor superfamily member 5; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDw40; GP39; HIGM1; I79_006806; IGM; IMD3; Immunoglobulin M; ImmunoglobulinM; membrane protein CD40; MGC9013; p50; receptor for ligand CD154; sCD40; soluble CD40; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
403469, 958

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA180944

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Antigen:
CD105

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P17813

Gene Symbols:
ENG

Immunogen:
Cell membrane antigens from fresh leukemia cells.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Equine, Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
SN6

Conjugate:
PE

Gene:
ENG

Gene Alias:
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100070421, 2022

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Lyophilized