PIMA182934

Complement C3b Monoclonal Antibody (H11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA182934-Each-of-1 In Stock ₹ 95,142.72

PIMA182934 - Each of 1

₹ 95,142.72

In Stock

Quantity

1

Base Price: ₹ 95,142.72

GST (18%): ₹ 17,125.69

Total Price: ₹ 1,12,268.41

Antigen

Complement C3b

Classification

Monoclonal

Concentration

50 μg/mL

Formulation

PBS with 0.5% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

P01024

Gene Symbols

C3

Immunogen

Human C3b

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Frozen), Western Blot

Clone

H11

Conjugate

Unconjugated

Gene

C3

Gene Alias

Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; Complement C3; Complement C3 alpha chain; Complement C3 beta chain; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3a; complement component C3b; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; iC3b; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

718

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

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Description

  • Reconstitute with 1 mL of distilled water
  • After reconstitution, store product undiluted at 4oC or -20oC if preferred
  • Mouse anti Human C3b antibody, clone H11 recognizes human C3b, part of the complement system
  • Inactive complement component 3b (iC3b) is a 42kDa neoantigen present in blood serum
  • Cleavage of C3b into iC3b by the protease factor I, in the presence of cofactors, changes the structure and resulting binding properties, preventing binding by complement factor B and properdin
  • This prevents further progression of the complement pathway, providing another mechanism by which the complement pathway may be regulated
  • iC3b is thought to play a role in inducing tolerance, binding complement receptor type 3 on antigen presenting cells and stimulating them to produce transforming growth factor beta2 and interleukin-10
  • It is thought to stimulate B-cells via the CD21 receptor providing a link between the innate and adaptive immune responses
  • Additionally iC3b acts as an opsonin which is recognised by complement receptor 3 expressed on leukocytes or complement receptor of the immunoglobulin superfamily (CRIg) on Kupffer cells, stimulating phagocytosis of the tagged cells
  • iC3b levels are often elevated in diseases such as Systemic Lupus Erythematosis and Rheumatoid arthritis.

Compare Similar Items

Show Difference

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Thermo Scientific

PIMA182934

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Antigen:
Complement C3b

Classification:
Monoclonal

Concentration:
50 μg/mL

Formulation:
PBS with 0.5% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P01024

Gene Symbols:
C3

Immunogen:
Human C3b

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Frozen), Western Blot

Clone:
H11

Conjugate:
Unconjugated

Gene:
C3

Gene Alias:
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; Complement C3; Complement C3 alpha chain; Complement C3 beta chain; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3a; complement component C3b; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; iC3b; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
718

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Img

Thermo Scientific

PIMA182975

--


Antigen:
Osteocalcin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P02818, P02820, P04640, P39056, Q8HYY9

Gene Symbols:
BGLAP

Immunogen:
Recombinant human osteocalcin GST fusion protein

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ELISA

Clone:
2H9F11F8

Conjugate:
Unconjugated

Gene:
BGLAP

Gene Alias:
Bglap; Bglap1; Bglap2; BGP; Bgpr; Bgpra; bone gamma carboxyglutamate protein; bone gamma carboxyglutamate protein 1; bone gamma-carboxyglutamate (gla) protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin); bone gamma-carboxyglutamate protein; bone gamma-carboxyglutamate protein 2; bone gamma-carboxyglutamate protein osteocalcin; bone gamma-carboxyglutamate; BGLAP; bone gamma-carboxyglutamic acid (Gla) protein (osteocalcin); bone Gla protein; bone gla protein BGP; bone Gla-protein; gamma-carbooxyglutamate (gla) protein; Gamma-carboxyglutamic acid-containing protein; GLA; Gla protein precusor; mOC-A; OC; OCN; OG1; Osteocalcin; PMF1; RP11-54H19.5; unnamed protein product

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100340503, 25295, 281646, 397530, 632

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA183002

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Antigen:
ApoA1

Classification:
Monoclonal

Concentration:
__

Formulation:
BBS, PBS with 1% dextran, 1% mannitol and no preservative

Gene Accession No.:
P02647

Gene Symbols:
APOA1

Immunogen:
Native Apo-A1 from human plasma.

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunohistochemistry (Frozen), Western Blot

Clone:
G2

Conjugate:
Unconjugated

Gene:
APOA1

Gene Alias:
1-Sep; 2-Sep; Alp-1; Apo a; APO A1; apo A-1; APO I; apo(a); APOA1; Apoa-1; ApoAI; Apo-AI; apoA-I; Apolipoprotein; Apolipoprotein A1; apolipoprotein A-1; Apolipoprotein AI; apolipoprotein A-I; apolipoprotein A-I precursor; Apolipoprotein A-I(1-242); Brp-14; Ltw-1; Lvtw-1; MGC102525; MGC117399; MGC124929; preproapolipoprotein A-I; prepro-apolipoprotein-AI; ProapoA-I; Proapolipoprotein A-I; Sep-1; Sep2; Sep-2; Truncated apolipoprotein A-I; Udpgt; Ugt1; Ugt1a7

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
335

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Img

Thermo Scientific

PIMA183016

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Antigen:
Bordetella pertussis Toxin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Native protein.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry

Clone:
1280/204

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
B. pertussis; PTx

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid