PIMA190001
HEF1 Monoclonal Antibody (14A11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA190001-Each-of-1 | In Stock | ₹ 47,956.38 |
PIMA190001 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,956.38
GST (18%): ₹ 8,632.148
Total Price: ₹ 56,588.528
Antigen
HEF1
Classification
Monoclonal
Conjugate
Unconjugated
Gene
NEDD9
Gene Alias
Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
4739
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunoprecipitation
Clone
14A11
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
Q14511
Gene Symbols
NEDD9
Immunogen
GST fusion protein, corresponding to amino acids 82-398 of Human HEF1.
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Related Products
Description
- MA1-90001 detects HEF1 from human samples
- HEF-1 is a multifunctional protein involved in integrin-based signaling that affects cell motility, growth, apoptosis and oncogenic transformation
- The Cas family of docking proteins have been the subject of intense research because of their role in cell motility, growth, apoptosis and oncogenic transformation
- These proteins are substrates of focal adhesion kinase (FAK) and the Src family of tyrosine kinases two active targets for drug development
- HEF1 protein production increases levels of mRNA transcripts that encode proteins associated with motility, cell transformation and invasiveness, including several metalloproteinases, MLCK, p160ROCK and ErbBi
- HEF1 overproduction also mediates apoptosis in epithelial-derived cell lines, including MCF7 and HeLa cells
- Recent clinical studies at another institution have found that overexpression of BCAR1 (p130Cas), a related protein, is associated with tamoxifen resistance
- This highlights the importance of studying the role of this family of proteins in cancer prognosis.
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Antigen: HEF1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: NEDD9
Gene Alias: Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 4739
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation
Clone: 14A11
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: Q14511
Gene Symbols: NEDD9
Immunogen: GST fusion protein, corresponding to amino acids 82-398 of Human HEF1.
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Antigen:
HEF1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
NEDD9
Gene Alias:
Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
4739
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation
Clone:
14A11
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
Q14511
Gene Symbols:
NEDD9
Immunogen:
GST fusion protein, corresponding to amino acids 82-398 of Human HEF1.
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Antigen: CA125
Classification: Monoclonal
Conjugate: Unconjugated
Gene: MUC16
Gene Alias: 1110008I14Rik; Ca125; CA-125; CA125 ovarian cancer antigen; ca-ovarian; FLJ14303; Gm1480; MUC16; MUC-16; mucin 16; mucin 16, cell surface associated; mucin-16; Ovarian cancer-related tumor marker CA125; ovarian carcinoma antigen CA125; RGD1308422
Host Species: Mouse
Purification Method: Ion-exchange chromatography
Regulatory Status: RUO
Gene ID (Entrez): 94025
Content And Storage: 4° C
Form: Liquid
Applications: ELISA, Flow Cytometry, Western Blot
Clone: X75
Formulation: PBS with 0.09% sodium azide, pH 7.4
Gene Accession No.: Q8WXI7
Gene Symbols: MUC16
Immunogen: CA-125 purified from human ovarian carcinoma.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
CA125
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
MUC16
Gene Alias:
1110008I14Rik; Ca125; CA-125; CA125 ovarian cancer antigen; ca-ovarian; FLJ14303; Gm1480; MUC16; MUC-16; mucin 16; mucin 16, cell surface associated; mucin-16; Ovarian cancer-related tumor marker CA125; ovarian carcinoma antigen CA125; RGD1308422
Host Species:
Mouse
Purification Method:
Ion-exchange chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
94025
Content And Storage:
4° C
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Western Blot
Clone:
X75
Formulation:
PBS with 0.09% sodium azide, pH 7.4
Gene Accession No.:
Q8WXI7
Gene Symbols:
MUC16
Immunogen:
CA-125 purified from human ovarian carcinoma.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: SIRP alpha
Classification: Monoclonal
Conjugate: FITC
Gene: SIRPA
Gene Alias: AI835480; Bit; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172; CD172 alpha; CD172 antigen-like family member A; CD172A; Inhibitory receptor SHPS-1; macrophage fusion receptor; Macrophage membrane protein MFP150; MFR; mSIRP-alpha1; Myd1; MYD-1; myD-1 antigen; p84; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); Ptpns1; SHP substrate 1; SHP-1; SHPS1; SHPS-1; signal regulatory protein alpha; signal-regulatory protein alpha; signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP; Sirpa; SIRPalpha; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3; swc3; swine workshop cluster 3 antigen; swine workshop cluster 3 antigen precursor; tyrosine phosphatase SHP substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1
Host Species: Mouse
Purification Method: IgG fraction
Regulatory Status: RUO
Gene ID (Entrez): 25528
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Radioimmune Assays (RIA)
Clone: MRC OX-41
Formulation: PBS with 0.5% BSA and 0.02% sodium azide
Gene Accession No.: P97710
Gene Symbols: SIRPA
Immunogen: Rat peritoneal macrophages
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG2a
Antigen:
SIRP alpha
Classification:
Monoclonal
Conjugate:
FITC
Gene:
SIRPA
Gene Alias:
AI835480; Bit; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172; CD172 alpha; CD172 antigen-like family member A; CD172A; Inhibitory receptor SHPS-1; macrophage fusion receptor; Macrophage membrane protein MFP150; MFR; mSIRP-alpha1; Myd1; MYD-1; myD-1 antigen; p84; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); Ptpns1; SHP substrate 1; SHP-1; SHPS1; SHPS-1; signal regulatory protein alpha; signal-regulatory protein alpha; signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP; Sirpa; SIRPalpha; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3; swc3; swine workshop cluster 3 antigen; swine workshop cluster 3 antigen precursor; tyrosine phosphatase SHP substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1
Host Species:
Mouse
Purification Method:
IgG fraction
Regulatory Status:
RUO
Gene ID (Entrez):
25528
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Radioimmune Assays (RIA)
Clone:
MRC OX-41
Formulation:
PBS with 0.5% BSA and 0.02% sodium azide
Gene Accession No.:
P97710
Gene Symbols:
SIRPA
Immunogen:
Rat peritoneal macrophages
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG2a
Antigen: Myb
Classification: Monoclonal
Conjugate: Unconjugated
Gene: MYB
Gene Alias: AI550390; Cmyb; c-myb; cmyb protein; c-myb_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; efg; gag-myb protein; M16449; MYB; myb proto-oncogene protein; MYB proto-oncogene, transcription factor; Mybl2; myb-related protein B; myeloblastosis oncogene; myeloblastosis oncogene-like 2; myeloblastosis proto-oncogene product; oncogene AMV; proto-oncogene c-Myb; RP1-32B1.1; transcription factor cmyb; transcriptional activator Myb; tumor-specific myb protein; v-myb avian myeloblastosis viral oncogene homolog
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 17863, 30519, 4602
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Clone: IOA3
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P06876, P10242
Gene Symbols: MYB
Immunogen: Recombinant v-myb protein, DNA binding protein
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, X. laevis, Zebrafish
Product Type: Antibody
Isotype: IgG2a
Antigen:
Myb
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
MYB
Gene Alias:
AI550390; Cmyb; c-myb; cmyb protein; c-myb_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; efg; gag-myb protein; M16449; MYB; myb proto-oncogene protein; MYB proto-oncogene, transcription factor; Mybl2; myb-related protein B; myeloblastosis oncogene; myeloblastosis oncogene-like 2; myeloblastosis proto-oncogene product; oncogene AMV; proto-oncogene c-Myb; RP1-32B1.1; transcription factor cmyb; transcriptional activator Myb; tumor-specific myb protein; v-myb avian myeloblastosis viral oncogene homolog
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
17863, 30519, 4602
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Clone:
IOA3
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P06876, P10242
Gene Symbols:
MYB
Immunogen:
Recombinant v-myb protein, DNA binding protein
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, X. laevis, Zebrafish
Product Type:
Antibody
Isotype:
IgG2a