PIMA190103
SIRP alpha Monoclonal Antibody (MRC OX-41), FITC, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA190103-Each-of-1 | In Stock | ₹ 45,731.82 |
PIMA190103 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,731.82
GST (18%): ₹ 8,231.728
Total Price: ₹ 53,963.548
Antigen
SIRP alpha
Classification
Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with 0.5% BSA and 0.02% sodium azide
Gene Accession No.
P97710
Gene Symbols
SIRPA
Immunogen
Rat peritoneal macrophages
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Rat
Product Type
Antibody
Isotype
IgG2a
Applications
Flow Cytometry, Immunocytochemistry, Radioimmune Assays (RIA)
Clone
MRC OX-41
Conjugate
FITC
Gene
SIRPA
Gene Alias
AI835480; Bit; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172; CD172 alpha; CD172 antigen-like family member A; CD172A; Inhibitory receptor SHPS-1; macrophage fusion receptor; Macrophage membrane protein MFP150; MFR; mSIRP-alpha1; Myd1; MYD-1; myD-1 antigen; p84; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); Ptpns1; SHP substrate 1; SHP-1; SHPS1; SHPS-1; signal regulatory protein alpha; signal-regulatory protein alpha; signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP; Sirpa; SIRPalpha; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3; swc3; swine workshop cluster 3 antigen; swine workshop cluster 3 antigen precursor; tyrosine phosphatase SHP substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1
Host Species
Mouse
Purification Method
IgG fraction
Regulatory Status
RUO
Gene ID (Entrez)
25528
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form
Liquid
Related Products
Description
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- SIRP alpha (CD172a, signal-regulatory protein alpha) is a receptor-type transmembrane glycoprotein expressed on cells of myeloid origin, including granulocytes, dendritic cells (DCs), macrophages, mast cells and hematopoietic stem cells
- SIRP alpha acts as a substrate for several activated tyrosine kinases, including EGFR, PDGFR, src and insulin receptor and is involved in the negative regulation of receptor tyrosine kinase-coupled signaling pathways
- The ligand binding of SIRP alpha to integrin-associated protein CD47 results in tyrosine kinase phosphorylation of immunoreceptor tyrosine-based inhibitory motifs (ITIMs) within the cytoplasmic region of SIRP alpha, which mediates the recruitment and activation of the tyrosine phosphatases SHP-1 and SHP-2
- Ligation of SIRP alpha with CD47 has been demonstrated in several regulatory processes, including the inhibition of host cell phagocytosis by macrophages and the bi-directional activation of T cells and DCs
- SIRP alpha has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion, and plays a general role in different physiological and pathological processes
- Cancer cells highly express CD47, which activates SIRP alpha and inhibits macrophage-mediated destruction of cancerous cell growth.
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Antigen: SIRP alpha
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 0.5% BSA and 0.02% sodium azide
Gene Accession No.: P97710
Gene Symbols: SIRPA
Immunogen: Rat peritoneal macrophages
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Immunocytochemistry, Radioimmune Assays (RIA)
Clone: MRC OX-41
Conjugate: FITC
Gene: SIRPA
Gene Alias: AI835480; Bit; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172; CD172 alpha; CD172 antigen-like family member A; CD172A; Inhibitory receptor SHPS-1; macrophage fusion receptor; Macrophage membrane protein MFP150; MFR; mSIRP-alpha1; Myd1; MYD-1; myD-1 antigen; p84; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); Ptpns1; SHP substrate 1; SHP-1; SHPS1; SHPS-1; signal regulatory protein alpha; signal-regulatory protein alpha; signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP; Sirpa; SIRPalpha; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3; swc3; swine workshop cluster 3 antigen; swine workshop cluster 3 antigen precursor; tyrosine phosphatase SHP substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1
Host Species: Mouse
Purification Method: IgG fraction
Regulatory Status: RUO
Gene ID (Entrez): 25528
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form: Liquid
Antigen:
SIRP alpha
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.5% BSA and 0.02% sodium azide
Gene Accession No.:
P97710
Gene Symbols:
SIRPA
Immunogen:
Rat peritoneal macrophages
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunocytochemistry, Radioimmune Assays (RIA)
Clone:
MRC OX-41
Conjugate:
FITC
Gene:
SIRPA
Gene Alias:
AI835480; Bit; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172; CD172 alpha; CD172 antigen-like family member A; CD172A; Inhibitory receptor SHPS-1; macrophage fusion receptor; Macrophage membrane protein MFP150; MFR; mSIRP-alpha1; Myd1; MYD-1; myD-1 antigen; p84; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); Ptpns1; SHP substrate 1; SHP-1; SHPS1; SHPS-1; signal regulatory protein alpha; signal-regulatory protein alpha; signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP; Sirpa; SIRPalpha; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3; swc3; swine workshop cluster 3 antigen; swine workshop cluster 3 antigen precursor; tyrosine phosphatase SHP substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1
Host Species:
Mouse
Purification Method:
IgG fraction
Regulatory Status:
RUO
Gene ID (Entrez):
25528
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form:
Liquid
Antigen: Myb
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P06876, P10242
Gene Symbols: MYB
Immunogen: Recombinant v-myb protein, DNA binding protein
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, X. laevis, Zebrafish
Product Type: Antibody
Isotype: IgG2a
Applications: Immunoprecipitation, Western Blot
Clone: IOA3
Conjugate: Unconjugated
Gene: MYB
Gene Alias: AI550390; Cmyb; c-myb; cmyb protein; c-myb_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; efg; gag-myb protein; M16449; MYB; myb proto-oncogene protein; MYB proto-oncogene, transcription factor; Mybl2; myb-related protein B; myeloblastosis oncogene; myeloblastosis oncogene-like 2; myeloblastosis proto-oncogene product; oncogene AMV; proto-oncogene c-Myb; RP1-32B1.1; transcription factor cmyb; transcriptional activator Myb; tumor-specific myb protein; v-myb avian myeloblastosis viral oncogene homolog
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 17863, 30519, 4602
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Myb
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P06876, P10242
Gene Symbols:
MYB
Immunogen:
Recombinant v-myb protein, DNA binding protein
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, X. laevis, Zebrafish
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunoprecipitation, Western Blot
Clone:
IOA3
Conjugate:
Unconjugated
Gene:
MYB
Gene Alias:
AI550390; Cmyb; c-myb; cmyb protein; c-myb_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; efg; gag-myb protein; M16449; MYB; myb proto-oncogene protein; MYB proto-oncogene, transcription factor; Mybl2; myb-related protein B; myeloblastosis oncogene; myeloblastosis oncogene-like 2; myeloblastosis proto-oncogene product; oncogene AMV; proto-oncogene c-Myb; RP1-32B1.1; transcription factor cmyb; transcriptional activator Myb; tumor-specific myb protein; v-myb avian myeloblastosis viral oncogene homolog
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
17863, 30519, 4602
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: alpha Synuclein
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: P37840
Gene Symbols: SNCA
Immunogen: Recombinant human alpha synuclein produced in E. coli.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Dot Blot, ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: 4B12
Conjugate: Unconjugated
Gene: SNCA
Gene Alias: Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)
Host Species: Mouse
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 6622
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
alpha Synuclein
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
P37840
Gene Symbols:
SNCA
Immunogen:
Recombinant human alpha synuclein produced in E. coli.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Dot Blot, ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
4B12
Conjugate:
Unconjugated
Gene:
SNCA
Gene Alias:
Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)
Host Species:
Mouse
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
6622
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Human Serum Albumin
Classification: Monoclonal
Concentration: 5.6 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.: P02768
Gene Symbols: ALB
Immunogen: Full length protein (Human)
Quantity: 1 mg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: ELISA, Western Blot
Clone: 15C7
Conjugate: Unconjugated
Gene: ALB
Gene Alias: Alb; Alb1; Alb-1; albumin; albumin (32 AA); albumin (AA 34); albumin 1; Albza; ANALBA; cell growth inhibiting protein 42; DKFZp779N1935; FDAH; GIG20; GIG42; growth-inhibiting protein 20; PRO0883; PRO0903; PRO1341; PRO1708; PRO2044; PRO2619; PRO2675; Serum albumin; UNQ696/PRO1341
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 213
Content And Storage: 4° C
Form: Liquid
Antigen:
Human Serum Albumin
Classification:
Monoclonal
Concentration:
5.6 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.:
P02768
Gene Symbols:
ALB
Immunogen:
Full length protein (Human)
Quantity:
1 mg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
ELISA, Western Blot
Clone:
15C7
Conjugate:
Unconjugated
Gene:
ALB
Gene Alias:
Alb; Alb1; Alb-1; albumin; albumin (32 AA); albumin (AA 34); albumin 1; Albza; ANALBA; cell growth inhibiting protein 42; DKFZp779N1935; FDAH; GIG20; GIG42; growth-inhibiting protein 20; PRO0883; PRO0903; PRO1341; PRO1708; PRO2044; PRO2619; PRO2675; Serum albumin; UNQ696/PRO1341
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
213
Content And Storage:
4° C
Form:
Liquid