PIMA516664
SIRP alpha Monoclonal Antibody (ED9), PE, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516664-Each-of-1 | In Stock | ₹ 63,271.62 |
PIMA516664 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 63,271.62
GST (18%): ₹ 11,388.892
Total Price: ₹ 74,660.512
Antigen
SIRP alpha
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.
P97710
Gene Symbols
SIRPA
Immunogen
Spleen cell homogenate
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Rat
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry
Clone
ED9
Conjugate
PE
Gene
SIRPA
Gene Alias
AI835480; Bit; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172; CD172 alpha; CD172 antigen-like family member A; CD172A; Inhibitory receptor SHPS-1; macrophage fusion receptor; Macrophage membrane protein MFP150; MFR; mSIRP-alpha1; Myd1; MYD-1; myD-1 antigen; p84; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); Ptpns1; SHP substrate 1; SHP-1; SHPS1; SHPS-1; signal regulatory protein alpha; signal-regulatory protein alpha; signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP; Sirpa; SIRPalpha; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3; swc3; swine workshop cluster 3 antigen; swine workshop cluster 3 antigen precursor; tyrosine phosphatase SHP substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
25528
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Lyophilized
Related Products
Description
- Reconstitute with 1 mL of distilled water
- After reconstitution, store product undiluted at 4oC in the dark
- For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
- SIRP alpha (CD172a, signal-regulatory protein alpha) is a receptor-type transmembrane glycoprotein expressed on cells of myeloid origin, including granulocytes, dendritic cells (DCs), macrophages, mast cells and hematopoietic stem cells
- SIRP alpha acts as a substrate for several activated tyrosine kinases, including EGFR, PDGFR, src and insulin receptor and is involved in the negative regulation of receptor tyrosine kinase-coupled signaling pathways
- The ligand binding of SIRP alpha to integrin-associated protein CD47 results in tyrosine kinase phosphorylation of immunoreceptor tyrosine-based inhibitory motifs (ITIMs) within the cytoplasmic region of SIRP alpha, which mediates the recruitment and activation of the tyrosine phosphatases SHP-1 and SHP-2
- Ligation of SIRP alpha with CD47 has been demonstrated in several regulatory processes, including the inhibition of host cell phagocytosis by macrophages and the bi-directional activation of T cells and DCs
- SIRP alpha has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion, and plays a general role in different physiological and pathological processes
- Cancer cells highly express CD47, which activates SIRP alpha and inhibits macrophage-mediated destruction of cancerous cell growth.
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Antigen: SIRP alpha
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.: P97710
Gene Symbols: SIRPA
Immunogen: Spleen cell homogenate
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Rat
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry
Clone: ED9
Conjugate: PE
Gene: SIRPA
Gene Alias: AI835480; Bit; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172; CD172 alpha; CD172 antigen-like family member A; CD172A; Inhibitory receptor SHPS-1; macrophage fusion receptor; Macrophage membrane protein MFP150; MFR; mSIRP-alpha1; Myd1; MYD-1; myD-1 antigen; p84; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); Ptpns1; SHP substrate 1; SHP-1; SHPS1; SHPS-1; signal regulatory protein alpha; signal-regulatory protein alpha; signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP; Sirpa; SIRPalpha; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3; swc3; swine workshop cluster 3 antigen; swine workshop cluster 3 antigen precursor; tyrosine phosphatase SHP substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 25528
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Lyophilized
Antigen:
SIRP alpha
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.:
P97710
Gene Symbols:
SIRPA
Immunogen:
Spleen cell homogenate
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
ED9
Conjugate:
PE
Gene:
SIRPA
Gene Alias:
AI835480; Bit; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172; CD172 alpha; CD172 antigen-like family member A; CD172A; Inhibitory receptor SHPS-1; macrophage fusion receptor; Macrophage membrane protein MFP150; MFR; mSIRP-alpha1; Myd1; MYD-1; myD-1 antigen; p84; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); Ptpns1; SHP substrate 1; SHP-1; SHPS1; SHPS-1; signal regulatory protein alpha; signal-regulatory protein alpha; signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP; Sirpa; SIRPalpha; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3; swc3; swine workshop cluster 3 antigen; swine workshop cluster 3 antigen precursor; tyrosine phosphatase SHP substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
25528
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Lyophilized
Antigen: Ly-6C
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 1% BSA and 0.09% sodium azide
Gene Accession No.: P0CW02
Gene Symbols: Ly6c1
Immunogen: Balb/c macrophage precursor cell hybrids
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry
Clone: ER-MP20
Conjugate: Biotin
Gene: Ly6c1
Gene Alias: AA682074; AA959465; Ly6c; Ly-6C; Ly6c1; Ly-6C1; Ly6c2; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6 complex, locus C1; lymphocyte antigen 6C1; Lymphocyte antigen Ly-6C
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 17067
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Ly-6C
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 1% BSA and 0.09% sodium azide
Gene Accession No.:
P0CW02
Gene Symbols:
Ly6c1
Immunogen:
Balb/c macrophage precursor cell hybrids
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry
Clone:
ER-MP20
Conjugate:
Biotin
Gene:
Ly6c1
Gene Alias:
AA682074; AA959465; Ly6c; Ly-6C; Ly6c1; Ly-6C1; Ly6c2; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6 complex, locus C1; lymphocyte antigen 6C1; Lymphocyte antigen Ly-6C
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
17067
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CD301
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P49300
Gene Symbols: CLEC10A
Immunogen: Balb/c macrophage precursor cell hybrids
Quantity: 250 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: ER-MP23
Conjugate: Unconjugated
Gene: CLEC10A
Gene Alias: CD301; CD301a; Clec10a; CLECSF13; CLECSF14; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived); C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 14 (macrophage-derived); C-type lectin domain family 10 member A; C-type lectin domain family 10, member A; C-type lectin superfamily member 14; HML; HML2; macrophage asialoglycoprotein-binding protein 1; macrophage galactose N-acetyl-galactosamine specific lectin 1; Macrophage galactose/N-acetylgalactosamine-specific lectin; Macrophage lectin 2; macrophage lectin 2 (calcium dependent); M-ASGP-BP-1; MGL; Mgl1; MMGL
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 17312
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD301
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P49300
Gene Symbols:
CLEC10A
Immunogen:
Balb/c macrophage precursor cell hybrids
Quantity:
250 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
ER-MP23
Conjugate:
Unconjugated
Gene:
CLEC10A
Gene Alias:
CD301; CD301a; Clec10a; CLECSF13; CLECSF14; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived); C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 14 (macrophage-derived); C-type lectin domain family 10 member A; C-type lectin domain family 10, member A; C-type lectin superfamily member 14; HML; HML2; macrophage asialoglycoprotein-binding protein 1; macrophage galactose N-acetyl-galactosamine specific lectin 1; Macrophage galactose/N-acetylgalactosamine-specific lectin; Macrophage lectin 2; macrophage lectin 2 (calcium dependent); M-ASGP-BP-1; MGL; Mgl1; MMGL
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
17312
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CD90
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P04216
Gene Symbols: Thy1
Immunogen: Purified human brain Thy-1.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Cynomolgus Monkey, Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone: F15-42-1
Conjugate: Unconjugated
Gene: Thy1
Gene Alias: CD7; CD90; CDw90; FLJ33325; membrane glycoprotein; T25; Thy 1.2; THY1; Thy-1; Thy-1 antigen; Thy-1 cell surface antigen; thy-1 glycoprotein; thy-1 membrane glycoprotein; Thy-1 protein; Thy-1 T-cell antigen; Thy1.1; Thy1.2; Thy-1.2; thymus cell antigen 1, theta; Thymus cell surface antigen
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 102139037, 7070
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD90
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P04216
Gene Symbols:
Thy1
Immunogen:
Purified human brain Thy-1.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Cynomolgus Monkey, Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone:
F15-42-1
Conjugate:
Unconjugated
Gene:
Thy1
Gene Alias:
CD7; CD90; CDw90; FLJ33325; membrane glycoprotein; T25; Thy 1.2; THY1; Thy-1; Thy-1 antigen; Thy-1 cell surface antigen; thy-1 glycoprotein; thy-1 membrane glycoprotein; Thy-1 protein; Thy-1 T-cell antigen; Thy1.1; Thy1.2; Thy-1.2; thymus cell antigen 1, theta; Thymus cell surface antigen
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
102139037, 7070
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid