PIMA511355

PCNA Monoclonal Antibody (PC10), Biotin, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA511355-Each-of-1 In Stock ₹ 51,250.44

PIMA511355 - Each of 1

₹ 51,250.44

In Stock

Quantity

1

Base Price: ₹ 51,250.44

GST (18%): ₹ 9,225.079

Total Price: ₹ 60,475.519

Antigen

PCNA

Classification

Monoclonal

Concentration

200 μg/mL

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

P04961, P12004

Gene Symbols

Pcna

Immunogen

Recombinant rat PCNA protein

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Canine, Human, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG2a κ

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

PC10

Conjugate

Biotin

Gene

Pcna

Gene Alias

ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; MGC8367; Pcna; pcna protein; Pcna/cyclin; PCNAR; POL30; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

25737, 477166, 5111

Content And Storage

4° C

Form

Liquid

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Description

  • Methanol fixation is required for immunofluorescence and flow cytometry staining
  • To decrease nonspecific staining for both applications, using a Biotin/Streptavidin blocker is recommended
  • By WB, MA5-11355 detects a predominant band between 30-35kD, and fainter nonspecific bands at ∽72kD and 130kD
  • PCNA (polymerase delta auxiliary protein) is essential for DNA replication and is involved in DNA excision and mismatch repair pathways
  • PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT)
  • PCNA is a potentially useful marker of cells with proliferative potential and for identifying the proliferation status of tumor tissue (i.e
  • relevant to prognosis)
  • PCNA is a marker for cells in early G1 phase and S phase of the cell cycle
  • PCNA is found in the nucleus and is a cofactor of DNA polymerase delta, and acts as a homotrimer and helps increase the processing of leading strand synthesis during DNA replication
  • In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway
  • Two transcript variants encoding the same protein have been found for PCNA
  • Pseudogenes of PCNA have been described on chromosome 4 and on the X chromosome.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA511355

--


Antigen:
PCNA

Classification:
Monoclonal

Concentration:
200 μg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P04961, P12004

Gene Symbols:
Pcna

Immunogen:
Recombinant rat PCNA protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
PC10

Conjugate:
Biotin

Gene:
Pcna

Gene Alias:
ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; MGC8367; Pcna; pcna protein; Pcna/cyclin; PCNAR; POL30; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
25737, 477166, 5111

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA511417

--


Antigen:
CD21

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
tissue culture supernatant with 0.09% sodium azide

Gene Accession No.:
P20023

Gene Symbols:
CR2

Immunogen:
Recombinant protein encoding the external domain of human CD21

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
2G9

Conjugate:
Unconjugated

Gene:
CR2

Gene Alias:
C3b/C4b receptor; C3-binding protein; C3BR; C3DR; C4BR; CD21; CD35; CD35 antigen; cell surface receptor for C3d; complement C3b/C4b receptor 1 (Knops blood group); complement C3d receptor; Complement C3d receptor (C3DR); complement C3d receptor 2; complement component (3b/4b) receptor 1 (Knops blood group); complement component (3d/Epstein Barr virus) receptor 2; complement component 3b/4b receptor 1 (Knops blood group); complement component 3d receptor 2; complement component receptor 2; complement receptor 1 long isoform; complement receptor 2; complement receptor type 1; complement receptor type 1-like protein; complement receptor type 2; Complement Receptor type 2 (CR2); CR; CR1; Cr-1; CR1-L; Cr2; Cr-2; CVID7; EBV receptor; EBV-R; Epstein-Barr virus receptor; EVBR; expressed in B lymphocytes; KN; Knops blood group antigen; LOW QUALITY PROTEIN: complement receptor type 1; SLEB9

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
1380

Content And Storage:
4° C

Form:
Liquid

Img

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PIMA511441

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Antigen:
Transferrin Receptor

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
tissue culture supernatant with 0.09% sodium azide

Gene Accession No.:
P02786, Q62351

Gene Symbols:
TFRC

Immunogen:
__

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
10F11

Conjugate:
Unconjugated

Gene:
TFRC

Gene Alias:
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
22042, 7037

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA511447

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Antigen:
VCAM-1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P19320, P29533

Gene Symbols:
VCAM1

Immunogen:
Stimulated human umbilical vein endothelial cells (HUVEC)

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone:
1.4C3

Conjugate:
Unconjugated

Gene:
VCAM1

Gene Alias:
adhesion molecule VCAM-1; CD106; CD106 antigen; DKFZp779G2333; INCAM100; INCAM-100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; vascular cell adhesion molecule; vascular cell adhesion molecule 1; vascular cell adhesion molecule-1; vascular cell adhesion protein 1; V-CAM 1; Vcam1; Vcam-1; VCAM1B

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
22329, 7412

Content And Storage:
4° C

Form:
Liquid