PIMA514344

E2F1 Monoclonal Antibody (KH95), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA514344-Each-of-1 In Stock ₹ 45,646.26

PIMA514344 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

E2F1

Classification

Monoclonal

Concentration

0.4 mg/mL

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

Q01094, Q61501

Gene Symbols

E2F1

Immunogen

Recombinant human E2F-1 protein

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG2a κ

Applications

Gel Shift, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

KH95

Conjugate

Unconjugated

Gene

E2F1

Gene Alias

E2F transcription factor 1; E2F1; E2F-1; mKIAA4009; PBR3; PRB-binding protein E2F-1; RBAP1; RBAP-1; RBBP3; RBBP-3; RBP3; Retinoblastoma-associated protein 1; retinoblastoma-binding protein 3; Transcription factor E2F1

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

13555, 1869

Content And Storage

4° C

Form

Liquid

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Description

  • MA5-14344 targets E2F-1 Transcription Factor in gel shift, immunofluorescence, immunohistochemistry (paraffin), immunoprecipitation, and Western blot applications and shows reactivity with Human and mouse samples
  • The MA5-14344 immunogen is recombinant human E2F-1 protein
  • The protein encoded by this gene is a member of the E2F family of transcription factors
  • The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses
  • The E2F proteins contain several evolutionally conserved domains found in most members of the family
  • These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain
  • This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain
  • This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner
  • It can mediate both cell proliferation and p53-dependent/independent apoptosis.

Compare Similar Items

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Img

Thermo Scientific

PIMA514344

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Antigen:
E2F1

Classification:
Monoclonal

Concentration:
0.4 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q01094, Q61501

Gene Symbols:
E2F1

Immunogen:
Recombinant human E2F-1 protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Gel Shift, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
KH95

Conjugate:
Unconjugated

Gene:
E2F1

Gene Alias:
E2F transcription factor 1; E2F1; E2F-1; mKIAA4009; PBR3; PRB-binding protein E2F-1; RBAP1; RBAP-1; RBBP3; RBBP-3; RBP3; Retinoblastoma-associated protein 1; retinoblastoma-binding protein 3; Transcription factor E2F1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
13555, 1869

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA514361

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Antigen:
p57 Kip2

Classification:
Monoclonal

Concentration:
0.05 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P49918, P49919

Gene Symbols:
CDKN1C

Immunogen:
Recombinant human p57Kip2 protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
KP39

Conjugate:
Unconjugated

Gene:
CDKN1C

Gene Alias:
AL024410; Beckwith Wiedemann syndrome (WBS); BWCR; BWS; CDKI; Cdkn1c; cyclin dependent kinase inhibitor 1C; Cyclin dependent kinase inhibitor 1C (CDKN1C); cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (P57); cyclin-dependent kinase inhibitor 1C (p57, Kip2); cyclin-dependent kinase inhibitor p57; IMAGE; KIP2; p57; p57 Kip2; p57(kip2); p57KIP2; p57KIP2 A3sh; WBS

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1028, 12577

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA514366

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Antigen:
Cdk5

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P49615, Q00535, Q03114

Gene Symbols:
CDK5

Immunogen:
Recombinant cdk5 protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
__

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
DC34

Conjugate:
Unconjugated

Gene:
CDK5

Gene Alias:
AW048668; Cdk5; CDK5 activator 1; CDK5-SV; CDKN5; Cell division protein kinase 5; CR6 protein kinase; Crk6; cyclin dependent kinase 5; cyclin-dependent kinase 5; cyclin-dependent-like kinase 5; LIS7; protein kinase CDK5 splicing; PSSALRE; Serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; TPKII catalytic subunit

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1020, 12568, 140908

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA514398

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Antigen:
c-Abl

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P00519

Gene Symbols:
ABL1

Immunogen:
Recombinant Abl protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 λ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
8E9

Conjugate:
Unconjugated

Gene:
ABL1

Gene Alias:
Abelson murine leukemia oncogene; Abelson murine leukemia viral (v-abl) oncogene homolog 1; abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Abl; Abl 1 antib; ABL proto-oncogene 1, non-receptor tyrosine kinase; Abl1; ABL2; ABLL; AI325092; ARG; B30; bcr/abl; bcr/c-abl oncogene protein; c-ABL; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-ABL1; E430008G22Rik; JTK7; p150; Proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; RP11-83J21.1; Tyrosine kinase ARG; tyrosine-protein kinase ABL1; v-abl; v-abl Abelson murine leukemia oncogene 1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene homolog 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
25

Content And Storage:
4° C

Form:
Liquid