PIMA514398
c-Abl Monoclonal Antibody (8E9), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514398-Each-of-1 | In Stock | ₹ 51,421.56 |
PIMA514398 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,421.56
GST (18%): ₹ 9,255.881
Total Price: ₹ 60,677.441
Antigen
c-Abl
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.
P00519
Gene Symbols
ABL1
Immunogen
Recombinant Abl protein
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 λ
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
8E9
Conjugate
Unconjugated
Gene
ABL1
Gene Alias
Abelson murine leukemia oncogene; Abelson murine leukemia viral (v-abl) oncogene homolog 1; abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Abl; Abl 1 antib; ABL proto-oncogene 1, non-receptor tyrosine kinase; Abl1; ABL2; ABLL; AI325092; ARG; B30; bcr/abl; bcr/c-abl oncogene protein; c-ABL; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-ABL1; E430008G22Rik; JTK7; p150; Proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; RP11-83J21.1; Tyrosine kinase ARG; tyrosine-protein kinase ABL1; v-abl; v-abl Abelson murine leukemia oncogene 1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene homolog 1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
25
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA5-14398 targets c-Abl in immunofluorescence, immunoprecipitation, immunohistochemistry (paraffin), and Western blot applications and shows reactivity with Human
- The MA5-14398 immunogen is recombinant Abl protein
- The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response
- Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns c-Abl into an oncogene
- The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for c-Abl
- In chronic myelogenous leukemia and a subset of acute lymphoblastic leukemias, the c-Abl proto oncogene undergoes a (9;22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome)
- As the result of the fusion of c-Abl sequences from chromosome 9 to the Bcr gene on chromosome 22
- The c-Abl oncogene was initially identified as the viral transforming gene of Abelson murine leukemia virus (A-MuLV)
- c-ABL potentially regulates DNA repair by activating the proapoptotic pathway when the DNA damage is too severe to be repaired.
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Antigen: c-Abl
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.: P00519
Gene Symbols: ABL1
Immunogen: Recombinant Abl protein
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 λ
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 8E9
Conjugate: Unconjugated
Gene: ABL1
Gene Alias: Abelson murine leukemia oncogene; Abelson murine leukemia viral (v-abl) oncogene homolog 1; abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Abl; Abl 1 antib; ABL proto-oncogene 1, non-receptor tyrosine kinase; Abl1; ABL2; ABLL; AI325092; ARG; B30; bcr/abl; bcr/c-abl oncogene protein; c-ABL; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-ABL1; E430008G22Rik; JTK7; p150; Proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; RP11-83J21.1; Tyrosine kinase ARG; tyrosine-protein kinase ABL1; v-abl; v-abl Abelson murine leukemia oncogene 1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene homolog 1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 25
Content And Storage: 4° C
Form: Liquid
Antigen:
c-Abl
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P00519
Gene Symbols:
ABL1
Immunogen:
Recombinant Abl protein
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 λ
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
8E9
Conjugate:
Unconjugated
Gene:
ABL1
Gene Alias:
Abelson murine leukemia oncogene; Abelson murine leukemia viral (v-abl) oncogene homolog 1; abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Abl; Abl 1 antib; ABL proto-oncogene 1, non-receptor tyrosine kinase; Abl1; ABL2; ABLL; AI325092; ARG; B30; bcr/abl; bcr/c-abl oncogene protein; c-ABL; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-ABL1; E430008G22Rik; JTK7; p150; Proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; RP11-83J21.1; Tyrosine kinase ARG; tyrosine-protein kinase ABL1; v-abl; v-abl Abelson murine leukemia oncogene 1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene homolog 1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
25
Content And Storage:
4° C
Form:
Liquid
Antigen: CD4/CD8
Classification: Cocktail
Concentration: __
Formulation: tissue culture supernatant with 0.09% sodium azide
Gene Accession No.: P01730, P01732, P10966
Gene Symbols: CD4, CD8A, CD8B
Immunogen: CD4-stimulated human leukocytes, CD8-synthetic peptide containing the 13 C-terminal amino acids of the cytoplasmic domain of the a-chain of the CD8 molecule
Quantity: 7 mL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 4B12, SP16, CD8-SP16
Conjugate: Unconjugated
Gene: CD8B
Gene Alias: BB154331; Cd4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; CD4 molecule; CD4 receptor; CD4mut; CD8; CD8 antigen; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide (p32); CD8 antigen, beta polypeptide 1 (p37); CD8A; CD8a molecule; CD8alpha; CD8b; CD8b molecule; CD8B1; CD8beta; L3T4; LEU2; Leu-2; Leu2 T-lymphocyte antigen; Ly-2; LY3; Ly-35; Ly-4; Ly-B; Lyt2; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); LYT3; MAL; OKT8 T-cell antigen; p32; P37; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T8 T-cell antigen; T-cell antigen Leu2; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-2; T-lymphocyte differentiation antigen T8/Leu-2
Host Species: Mixed, Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 920, 925, 926
Content And Storage: 4° C
Form: Liquid
Antigen:
CD4/CD8
Classification:
Cocktail
Concentration:
__
Formulation:
tissue culture supernatant with 0.09% sodium azide
Gene Accession No.:
P01730, P01732, P10966
Gene Symbols:
CD4, CD8A, CD8B
Immunogen:
CD4-stimulated human leukocytes, CD8-synthetic peptide containing the 13 C-terminal amino acids of the cytoplasmic domain of the a-chain of the CD8 molecule
Quantity:
7 mL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
4B12, SP16, CD8-SP16
Conjugate:
Unconjugated
Gene:
CD8B
Gene Alias:
BB154331; Cd4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; CD4 molecule; CD4 receptor; CD4mut; CD8; CD8 antigen; CD8 antigen, alpha chain; CD8 antigen, alpha polypeptide (p32); CD8 antigen, beta polypeptide 1 (p37); CD8A; CD8a molecule; CD8alpha; CD8b; CD8b molecule; CD8B1; CD8beta; L3T4; LEU2; Leu-2; Leu2 T-lymphocyte antigen; Ly-2; LY3; Ly-35; Ly-4; Ly-B; Lyt2; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); LYT3; MAL; OKT8 T-cell antigen; p32; P37; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T8 T-cell antigen; T-cell antigen Leu2; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-2; T-lymphocyte differentiation antigen T8/Leu-2
Host Species:
Mixed, Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
920, 925, 926
Content And Storage:
4° C
Form:
Liquid
Antigen: CD3/CD20
Classification: Cocktail
Concentration: __
Formulation: tris HCl with proprietary stabilizer and <0.1% sodium azide; pH 7.6
Gene Accession No.: P04234, P04235, P07766, P09693, P11836, P11942, P19377, P19437, P22646, Q64159
Gene Symbols: CD3D, Cd3e, CD3G, MS4A1
Immunogen: synthetic 13-mer peptide corresponding to aa 156-168 of the epsilon chain of human CD3 protien; CD20- Human tonsil B cells
Quantity: 7 mL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2a κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: CD3-SP7; CD20-L26
Conjugate: Unconjugated
Gene: MS4A1
Gene Alias: AA960661; AI504783; B1; B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; CD20; CD20 antigen; CD20 receptor; CD3; CD3 antigen delta polypeptide; CD3 antigen, delta polypeptide; CD3 antigen, delta subunit; CD3 antigen, epsilon polypeptide; CD3 antigen, gamma polypeptide; CD3 delta; CD3 gamma-chain; CD3 molecule delta polypeptide; CD3 molecule, delta; CD3 molecule, epsilon; CD3 molecule, epsilon polypeptide; CD3 molecule, gamma; CD3 molecule, gamma polypeptide; Cd3d; CD3d antigen, delta polypeptide (TiT3 complex); CD3d molecule; CD3d molecule, delta (CD3-TCR complex); CD3-DELTA; Cd3e; CD3e antigen, epsilon polypeptide (TiT3 complex); CD3e molecule; CD3e molecule, epsilon (CD3-TCR complex); CD3epsilon; CD3-epsilon; CD3g; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule; CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); CD3-GAMMA; Ctg3; Ctg-3; CVID5; IMD1
Host Species: Mixed, Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 12482, 12500, 12501, 12502, 25710, 300678, 309217, 315609, 915, 916, 917, 931
Content And Storage: 4° C
Form: Liquid
Antigen:
CD3/CD20
Classification:
Cocktail
Concentration:
__
Formulation:
tris HCl with proprietary stabilizer and <0.1% sodium azide; pH 7.6
Gene Accession No.:
P04234, P04235, P07766, P09693, P11836, P11942, P19377, P19437, P22646, Q64159
Gene Symbols:
CD3D, Cd3e, CD3G, MS4A1
Immunogen:
synthetic 13-mer peptide corresponding to aa 156-168 of the epsilon chain of human CD3 protien; CD20- Human tonsil B cells
Quantity:
7 mL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
CD3-SP7; CD20-L26
Conjugate:
Unconjugated
Gene:
MS4A1
Gene Alias:
AA960661; AI504783; B1; B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; CD20; CD20 antigen; CD20 receptor; CD3; CD3 antigen delta polypeptide; CD3 antigen, delta polypeptide; CD3 antigen, delta subunit; CD3 antigen, epsilon polypeptide; CD3 antigen, gamma polypeptide; CD3 delta; CD3 gamma-chain; CD3 molecule delta polypeptide; CD3 molecule, delta; CD3 molecule, epsilon; CD3 molecule, epsilon polypeptide; CD3 molecule, gamma; CD3 molecule, gamma polypeptide; Cd3d; CD3d antigen, delta polypeptide (TiT3 complex); CD3d molecule; CD3d molecule, delta (CD3-TCR complex); CD3-DELTA; Cd3e; CD3e antigen, epsilon polypeptide (TiT3 complex); CD3e molecule; CD3e molecule, epsilon (CD3-TCR complex); CD3epsilon; CD3-epsilon; CD3g; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule; CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); CD3-GAMMA; Ctg3; Ctg-3; CVID5; IMD1
Host Species:
Mixed, Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
12482, 12500, 12501, 12502, 25710, 300678, 309217, 315609, 915, 916, 917, 931
Content And Storage:
4° C
Form:
Liquid
Antigen: Kappa/Lambda
Classification: Cocktail
Concentration: __
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.: P01834
Gene Symbols: IGKC
Immunogen: Kappa: B lymphoma cells. Lambda: light chains purified from human Bence-Jones proteins
Quantity: 7 mL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin)
Clone: L1C1
Conjugate: Unconjugated
Gene: IGKC
Gene Alias: HCAK1; IGKC; IGKCD; IGLV; IGLV@; immunoglobulin kappa constant; immunoglobulin lambda variable cluster; Km
Host Species: Mixed
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 3514
Content And Storage: 4° C
Form: Liquid
Antigen:
Kappa/Lambda
Classification:
Cocktail
Concentration:
__
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P01834
Gene Symbols:
IGKC
Immunogen:
Kappa: B lymphoma cells. Lambda: light chains purified from human Bence-Jones proteins
Quantity:
7 mL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin)
Clone:
L1C1
Conjugate:
Unconjugated
Gene:
IGKC
Gene Alias:
HCAK1; IGKC; IGKCD; IGLV; IGLV@; immunoglobulin kappa constant; immunoglobulin lambda variable cluster; Km
Host Species:
Mixed
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
3514
Content And Storage:
4° C
Form:
Liquid