PIMA514528

ALK Monoclonal Antibody (SP8), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA514528-Each-of-1 In Stock ₹ 53,475.00

PIMA514528 - Each of 1

₹ 53,475.00

In Stock

Quantity

1

Base Price: ₹ 53,475.00

GST (18%): ₹ 9,625.50

Total Price: ₹ 63,100.50

Antigen

ALK

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

tissue culture supernatant diluted in TBS with 1% BSA and 0.1% sodium azide; pH 7.5

Gene Accession No.

P97793, Q9UM73

Gene Symbols

ALK

Immunogen

Recombinant protein corresponding to a region, which spans the tyrosine kinase catalytic domain and part of the C-terminus of the NPM-ALK transcript

Regulatory Status

RUO

Gene ID (Entrez)

11682, 238

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone

SP8

Conjugate

Unconjugated

Gene

ALK

Gene Alias

Alk; ALK tyrosine kinase receptor; ALK/NPM1 fusion gene; anaplastic lymphoma kinase; Anaplastic lymphoma kinase Ki1; Anaplastic Lymphoma Kinase p80; anaplastic lymphoma receptor tyrosine kinase; CD246; CD246 antigen; EC 2.7.10.1; kinase ALK; mutant anaplastic lymphoma kinase; NBLST3; npm-alk; p80; Tcrz; TFG/ALK

Host Species

Rabbit

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • MA5-14528 targets ALK (Anaplastic Lymphoma Kinase) / p80 in IHC (P) and ICC/IF applications and shows reactivity with Human and Mouse samples
  • The MA5-14528 immunogen is recombinant protein corresponding to a region, which spans the tyrosine kinase catalytic domain and part of the C-terminus of the NPM-ALK transcript
  • Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) belongs to the insulin receptor superfamily
  • It is vital for brain development
  • Mutations, rearrangements, and amplifications in the ALK gene have been found in tumors, including anaplastic large cell lymphoma, neurblastoma, and non-small cell lung cancer
  • Chromosomal rearrangement is the most common genetic alteration
  • The translocation creates a fusion gene consisting of the ALK gene and the nucleophosmin gene: the 3' half of ALK, derived from chromosome 2, is fused to the 5' portion of NPM from chromosome 5
  • A recent study shows that the product of the NPM-ALK fusion gene is oncogenic
  • The deduced amino acid sequences reveal that ALK is a novel receptor protein-tyrosine kinase having a putative transmembrane domain and an extracellular domain
  • These sequences are absent in the product of the transforming NPM-ALK gene
  • ALK shows the greatest sequence similarity to LTK
  • ALK plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system.

Compare Similar Items

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Img

Thermo Scientific

PIMA514528

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Antigen:
ALK

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
tissue culture supernatant diluted in TBS with 1% BSA and 0.1% sodium azide; pH 7.5

Gene Accession No.:
P97793, Q9UM73

Gene Symbols:
ALK

Immunogen:
Recombinant protein corresponding to a region, which spans the tyrosine kinase catalytic domain and part of the C-terminus of the NPM-ALK transcript

Regulatory Status:
RUO

Gene ID (Entrez):
11682, 238

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
SP8

Conjugate:
Unconjugated

Gene:
ALK

Gene Alias:
Alk; ALK tyrosine kinase receptor; ALK/NPM1 fusion gene; anaplastic lymphoma kinase; Anaplastic lymphoma kinase Ki1; Anaplastic Lymphoma Kinase p80; anaplastic lymphoma receptor tyrosine kinase; CD246; CD246 antigen; EC 2.7.10.1; kinase ALK; mutant anaplastic lymphoma kinase; NBLST3; npm-alk; p80; Tcrz; TFG/ALK

Host Species:
Rabbit

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIMA514532

--


Antigen:
Synaptophysin

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
tissue culture supernatant diluted in TBS with 1% BSA and 0.1% sodium azide; pH 7.5

Gene Accession No.:
P07825, P08247, Q62277

Gene Symbols:
Syp

Immunogen:
A synthetic peptide of human synaptophysin

Regulatory Status:
RUO

Gene ID (Entrez):
20977, 24804, 6855

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP11

Conjugate:
Unconjugated

Gene:
Syp

Gene Alias:
A230093K24Rik; AI848995; BM89 antigen; I79_012252; Major synaptic vesicle protein p38; MRX96; MRXSYP; p38; Syn; Synaptophysin; Syp; Syp I; Syp1

Host Species:
Rabbit

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIMA514536

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Antigen:
Chromogranin A

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
tissue culture supernatant diluted in TBS with 1% BSA and 0.1% sodium azide; pH 7.5

Gene Accession No.:
P10354, P10645

Gene Symbols:
Chga

Immunogen:
Recombinant protein encoding human chromogranin A

Regulatory Status:
RUO

Gene ID (Entrez):
1113, 24258

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
SP12

Conjugate:
Unconjugated

Gene:
Chga

Gene Alias:
AL-11; AL26; Beta-granin; betagranin (N-terminal fragment of chromogranin A); catestatin; CgA; CHGA; ChrA; chromofungin; chromogranin A; chromogranin A (parathyroid secretory protein 1); chromogranin A precursor; chromogranin-A; CTNNB; DKFZp686D02253; EA-92; ER-37; ES-43; FLJ25606; FLJ37923; GE-25; GR-44; GV-19; LF-19; LOW QUALITY PROTEIN: chromogranin-A; MGC105435; Pancreastatin; Parastatin; parathyroid secretory protein 1; p-Glu serpinin precursor; pituitary secretory protein I; Serpinin; Serpinin-RRG; SL21; SP-I; SS-18; Vasostatin I; Vasostatin II; Vasostatin-1; Vasostatin-2; WA-8; WE-14

Host Species:
Rabbit

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIMA514540

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Antigen:
Calretinin

Classification:
Monoclonal

Concentration:
0.037 mg/mL

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P22676, P47728, Q08331

Gene Symbols:
CALB2

Immunogen:
Recombinant full-length mouse calretinin protein

Regulatory Status:
RUO

Gene ID (Entrez):
117059, 12308, 794

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
SP13

Conjugate:
Unconjugated

Gene:
CALB2

Gene Alias:
29 kDa calbindin; 29kD calretinin; 29kDa calbindin; CAB29; CAL2; Calb2; calbindin 2; calbindin 2, (29kD, calretinin); calbindin 2, 29kDa; calbindin D29K; calretinin; CR; testicular secretory protein Li 8

Host Species:
Rabbit

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG