PIMA514822

Phospho-STAT5 alpha (Tyr694) Monoclonal Antibody (J.536.2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA514822-Each-of-1 In Stock ₹ 45,304.02

PIMA514822 - Each of 1

₹ 45,304.02

In Stock

Quantity

1

Base Price: ₹ 45,304.02

GST (18%): ₹ 8,154.724

Total Price: ₹ 53,458.744

Antigen

Phospho-STAT5 alpha (Tyr694)

Classification

Monoclonal

Concentration

592 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P42229, P42230

Gene Symbols

STAT5A

Immunogen

Synthetic peptide corresponding to residues surrounding Tyr694 of Stat5

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

J.536.2

Conjugate

Unconjugated

Gene

STAT5A

Gene Alias

AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20850, 6776

Content And Storage

-20°C

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA514973

--

Img

Thermo Scientific

PIMA514920

--

Img

Thermo Scientific

PIMA515129

--

Img

Thermo Scientific

PIMA515712

--

Img

Thermo Scientific

PIMA515659

--

Img

Thermo Scientific

PIMA515473

--

Img

Thermo Scientific

PIMA514965

--

Img

Thermo Scientific

PIMA514821

--

Description

  • It is not recommended to aliquot this antibody
  • STAT5 alpha is a member of the STAT family of transcription factors
  • In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators
  • STAT5 alpha is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones
  • Activation of STAT5 alpha in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis
  • The mouse counterpart of STAT5 alpha is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this protein in cells
  • STAT5 alpha, along with STAT5 beta, were identified in mouse
  • The amino acid sequences of STAT5 alpha and STAT5 beta show 96% sequence similarity, and both proteins are co expressed in most tissues in virgin and lactating mice
  • However, differential accumulation of STAT5 alpha and STAT5 beta mRNA has been reported for both muscle and mammary tissue
  • STAT5 alpha is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA514822

--


Antigen:
Phospho-STAT5 alpha (Tyr694)

Classification:
Monoclonal

Concentration:
592 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P42229, P42230

Gene Symbols:
STAT5A

Immunogen:
Synthetic peptide corresponding to residues surrounding Tyr694 of Stat5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
J.536.2

Conjugate:
Unconjugated

Gene:
STAT5A

Gene Alias:
AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20850, 6776

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514823

--


Antigen:
Phospho-PDGFRB (Tyr751)

Classification:
Monoclonal

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P05622, P09619, Q05030

Gene Symbols:
Pdgfrb

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr751 of human PDGF receptor β

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
G.13.6

Conjugate:
Unconjugated

Gene:
Pdgfrb

Gene Alias:
AI528809; Beta platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140B; CD140b antigen; IBGC4; IMF1; JTK12; KOGS; PDGF beta chain; PDGF Receptor beta; Pdgfr; Pdgfr1; PDGFR-1; PDGFRB; PDGF-R-beta; PDGFR-beta; PENTT; platelet derived growth factor receptor beta; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18596, 24629, 5159

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514826

--


Antigen:
Phospho-MAP2K4 (Ser257)

Classification:
Monoclonal

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P45985, P47809

Gene Symbols:
MAP2K4

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer257/Thr261 of human SEK1/MKK4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot

Clone:
G.674.10

Conjugate:
Unconjugated

Gene:
MAP2K4

Gene Alias:
C-JUN N-terminal kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 2; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4a; JNK kinase 1; JNK-activated kinase 1; JNK-activating kinase 1; JNKK; JNKK 1; JNKK1; MAP kinase activator 2; MAP kinase kinase 4; Map2k4; map2k4.L; map2k4a; map2k4-a; map2k4-b; MAP2K4delta; MAPK/ERK kinase 4; MAPKK 4; MAPKK4; MEK 4; MEK4; mitogen activated protein kinase kinase 4; mitogen activated protein kinase kinase 4, variant 1; mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4 L homeolog; mitogen-activated protein kinase kinase 4a; MKK4; mkk4a; MKK4A-l; PRKMK4; SAPK kinase 1; SAPK/ERK kinase 1; SAPK/Erk/kinase 1; SAPKK1; SAPKK-1; Sek1; Serk1; Skk1; Stress-activated protein kinase kinase 1; XELAEV_18044157mg; XMEK2; zgc:136500; zMKK4 protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26398, 287398, 6416

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514831

--


Antigen:
LKB1

Classification:
Monoclonal

Concentration:
24 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
D4AE59, Q15831, Q9WTK7

Gene Symbols:
STK11

Immunogen:
An LKB1 partial fusion protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
E.425.6

Conjugate:
Unconjugated

Gene:
STK11

Gene Alias:
AA408040; CAMK group; CAMKL family; hLKB1; liver kinase B1; Liver kinase B1 homolog; LKB 1; LKB1; LKB-1; LKB1(S); Par-4; PJS; polarization-related protein LKB1; R75140; renal carcinoma antigen NY-REN-19; serine/threonine kinase 11; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11; STK11

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20869, 314621, 6794

Content And Storage:
-20°C

Form:
Liquid