PIMA515712
STAT3 Monoclonal Antibody (3B5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515712-Each-of-1 | In Stock | ₹ 53,475.00 |
PIMA515712 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,475.00
GST (18%): ₹ 9,625.50
Total Price: ₹ 63,100.50
Antigen
STAT3
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P40763, P42227, P52631
Gene Symbols
STAT3
Immunogen
Purified recombinant fragment of human STAT3 expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
20848, 25125, 6774
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
3B5
Conjugate
Unconjugated
Gene
STAT3
Gene Alias
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15712 targets STAT3 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human, mouse, and Non-human primate samples
- The MA5-15712 immunogen is purified recombinant fragment of human STAT3 expressed in E
- Coli
- MA5-15712 detects STAT3 which has a predicted molecular weight of approximately 88kDa
- STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
- Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
- STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
- Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
- In humans, the STAT3 gene is located on the q arm of chromosome 17
- STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
- The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
- STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
- The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
- Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
- Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.
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Antigen: STAT3
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: P40763, P42227, P52631
Gene Symbols: STAT3
Immunogen: Purified recombinant fragment of human STAT3 expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 20848, 25125, 6774
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 3B5
Conjugate: Unconjugated
Gene: STAT3
Gene Alias: 1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG1
Antigen:
STAT3
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
P40763, P42227, P52631
Gene Symbols:
STAT3
Immunogen:
Purified recombinant fragment of human STAT3 expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
20848, 25125, 6774
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
3B5
Conjugate:
Unconjugated
Gene:
STAT3
Gene Alias:
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG1
Antigen: TAB2
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: Q9NYJ8
Gene Symbols: Tab2
Immunogen: Purified recombinant fragment of human TAB2 expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 23118
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Flow Cytometry, Western Blot
Clone: 3B5
Conjugate: Unconjugated
Gene: Tab2
Gene Alias: 1110030N06Rik; A530078N03Rik; CHTD2; FLJ21885; KIAA0733; MAP3K7IP2; mitogen activated protein kinase kinase kinase 7 interacting protein 2; mitogen-activated protein kinase kinase kinase 7 interacting protein 2; mitogen-activated protein kinase kinase kinase 7-interacting protein 2; mKIAA0733; OTTHUMP00000017388; Tab2; TAB-2; Tak1 binding protein 2; TAK1-binding protein 2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2; TGF-beta activated kinase 1/MAP3K7 binding protein 2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; TGF-beta-activated kinase 1-binding protein 2
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
TAB2
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
Q9NYJ8
Gene Symbols:
Tab2
Immunogen:
Purified recombinant fragment of human TAB2 expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
23118
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Western Blot
Clone:
3B5
Conjugate:
Unconjugated
Gene:
Tab2
Gene Alias:
1110030N06Rik; A530078N03Rik; CHTD2; FLJ21885; KIAA0733; MAP3K7IP2; mitogen activated protein kinase kinase kinase 7 interacting protein 2; mitogen-activated protein kinase kinase kinase 7 interacting protein 2; mitogen-activated protein kinase kinase kinase 7-interacting protein 2; mKIAA0733; OTTHUMP00000017388; Tab2; TAB-2; Tak1 binding protein 2; TAK1-binding protein 2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2; TGF-beta activated kinase 1/MAP3K7 binding protein 2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; TGF-beta-activated kinase 1-binding protein 2
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: Cyclin B1
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: P14635, P30277
Gene Symbols: Ccnb1
Immunogen: Purified recombinant fragment of human CCNB1 expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 25203, 891
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone: 5G6
Conjugate: Unconjugated
Gene: Ccnb1
Gene Alias: Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG1
Antigen:
Cyclin B1
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
P14635, P30277
Gene Symbols:
Ccnb1
Immunogen:
Purified recombinant fragment of human CCNB1 expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
25203, 891
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
5G6
Conjugate:
Unconjugated
Gene:
Ccnb1
Gene Alias:
Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG1
Antigen: Mammaglobin A
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: Q13296
Gene Symbols: SCGB2A2
Immunogen: Purified recombinant fragment of human SCGB2A2 expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 4250
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 3C8
Conjugate: Unconjugated
Gene: SCGB2A2
Gene Alias: C3.1; HGNC:7050; mammaglobin 1; mammaglobin A; Mammaglobin-1; Mammaglobin-A; MGB1; MGC71974; prostatein; prostatein C3 subunit; prostatein peptide C3; prostatic steroid binding protein, allele C3(1); prostatic steroid-binding protein C3; Psbpc3; SCGB2A2; Secretoglobin family 2A member 2; secretoglobin, family 2A, member 2; UGB2
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
Mammaglobin A
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
Q13296
Gene Symbols:
SCGB2A2
Immunogen:
Purified recombinant fragment of human SCGB2A2 expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
4250
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
3C8
Conjugate:
Unconjugated
Gene:
SCGB2A2
Gene Alias:
C3.1; HGNC:7050; mammaglobin 1; mammaglobin A; Mammaglobin-1; Mammaglobin-A; MGB1; MGC71974; prostatein; prostatein C3 subunit; prostatein peptide C3; prostatic steroid binding protein, allele C3(1); prostatic steroid-binding protein C3; Psbpc3; SCGB2A2; Secretoglobin family 2A member 2; secretoglobin, family 2A, member 2; UGB2
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1