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PIMA514857

Phospho-IKK alpha/beta (Ser176, Ser177) Monoclonal Antibody (J.10.3), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size	SKU	Availability	Price
Each of 1	PIMA514857-Each-of-1	In Stock	₹ 45,304.02

PIMA514857 - Each of 1

₹ 45,304.02

In Stock

Quantity

Base Price: ₹ 45,304.02

GST (18%): ₹ 8,154.724

Total Price: ₹ 53,458.744

Antigen

Phospho-IKK alpha/beta (Ser176, Ser177)

Classification

Monoclonal

Concentration

88 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

O14920, O15111, O88351, Q60680

Gene Symbols

CHUK, Ikbkb

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pSer177 of IKKβ

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

J.10.3

Conjugate

Unconjugated

Gene

Ikbkb

Gene Alias

AI132552; AI256658; AIM-1; CHUK; Chuk1; component of inhibitor of nuclear factor kappa B kinase complex; conserved helix-loop-helix ubiquitous kinase; EC 2.7.11.10; Fbx24; Fbxo24; I kappa B kinase 1; i kappa-B kinase alpha; IkappaB kinase; I-kappa-B kinase 1; I-kappa-B kinase 2; IkappaB kinase alpha; I-kappa-B kinase alpha; I-kappa-B kinase-alpha; I-kappa-B-kinase beta; IkB kinase alpha subunit; IkB kinase-alpha; IkB kinase-beta; ikBKA; Ikbkb; IKK alpha; IKK[b]; IKK1; IKK2; IKK-2; IKKA; IKK-A; IKK-a kinase; IKK-alpha; Ikkb; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa B kinase subunit beta; inhibitor of nuclear factor kappa-B kinase subunit alpha; Inhibitor of nuclear factor kappa-B kinase subunit beta; NFKBIKA; NFKBIKB; Nuclear factor NFkappaB inhibitor kinase alpha; nuclear factor NF-kappa-B inhibitor kinase alpha; Nuclear factor NF-kappa-B inhibitor kinase beta; TCF16; TCF-16; TCF17; Transcription factor 16

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1147, 12675, 16150, 3551

Content And Storage

-20°C

Form

Liquid

Related Products

Description

It is not recommended to aliquot this antibody
IKK alpha/beta is encoded by CHUK (conserved helix-loop-helix ubiquitous kinase) and IKKB (inhibitor of kappa light polypeptide gene enhancer in B-cells) gene located in chromosome 10 and 8 respectively in humans
Upon stimulation by agents that activate the NF-kB pathway such as TNF alpha, the two subunits of IKK complex, IKK alpha and IKK -beta alongside a regulator NEMO (IKK gamma) phosphorylates IkB proteins
This targets the later for ubiquitin mediated degradation and phosphorylation of NF-kB leading to subsequent translocation to the nucleus
Phosphorylation at serine 176 and 180 located in the activation loop causes a confirmation change that is required for the activation of the kinases.

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Thermo Scientific

PIMA514857

Antigen:

Phospho-IKK alpha/beta (Ser176, Ser177)

Classification:

Monoclonal

Concentration:

88 μg/mL

Formulation:

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:

O14920, O15111, O88351, Q60680

Gene Symbols:

CHUK, Ikbkb

Immunogen:

Synthetic phosphopeptide corresponding to residues surrounding pSer177 of IKKβ

Quantity:

100 μL

Primary or Secondary:

Primary

Target Species:

Human, Mouse

Product Type:

Antibody

Isotype:

IgG

Applications:

Western Blot

Clone:

J.10.3

Conjugate:

Unconjugated

Gene:

Ikbkb

Gene Alias:

AI132552; AI256658; AIM-1; CHUK; Chuk1; component of inhibitor of nuclear factor kappa B kinase complex; conserved helix-loop-helix ubiquitous kinase; EC 2.7.11.10; Fbx24; Fbxo24; I kappa B kinase 1; i kappa-B kinase alpha; IkappaB kinase; I-kappa-B kinase 1; I-kappa-B kinase 2; IkappaB kinase alpha; I-kappa-B kinase alpha; I-kappa-B kinase-alpha; I-kappa-B-kinase beta; IkB kinase alpha subunit; IkB kinase-alpha; IkB kinase-beta; ikBKA; Ikbkb; IKK alpha; IKK[b]; IKK1; IKK2; IKK-2; IKKA; IKK-A; IKK-a kinase; IKK-alpha; Ikkb; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa B kinase subunit beta; inhibitor of nuclear factor kappa-B kinase subunit alpha; Inhibitor of nuclear factor kappa-B kinase subunit beta; NFKBIKA; NFKBIKB; Nuclear factor NFkappaB inhibitor kinase alpha; nuclear factor NF-kappa-B inhibitor kinase alpha; Nuclear factor NF-kappa-B inhibitor kinase beta; TCF16; TCF-16; TCF17; Transcription factor 16

Host Species:

Rabbit

Purification Method:

Affinity chromatography

Regulatory Status:

RUO

Gene ID (Entrez):

1147, 12675, 16150, 3551

Content And Storage:

-20°C

Form:

Liquid

Thermo Scientific

PIMA514858

Antigen:

Syntaxin 6

Classification:

Monoclonal

Concentration:

164 μg/mL

Formulation:

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:

O43752, Q63635, Q9JKK1

Gene Symbols:

STX6

Immunogen:

Synthetic peptide corresponding to residues surrounding Tyr140 of mouse syntaxin 6 protein

Quantity:

100 μL

Primary or Secondary:

Primary

Target Species:

Human, Mouse, Rat

Product Type:

Antibody

Isotype:

IgG

Applications:

Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:

F.374.2

Conjugate:

Unconjugated

Gene:

STX6

Gene Alias:

2310039E05Rik; 2410005I16Rik; AA437559; AI415714; AI845861; HGNC:11441; STX6; Syn6; syntaxin 6; syntaxin-6

Host Species:

Rabbit

Purification Method:

Affinity chromatography

Regulatory Status:

RUO

Gene ID (Entrez):

10228, 58244, 60562

Content And Storage:

-20°C

Form:

Liquid

Thermo Scientific

PIMA514859

Antigen:

Phospho-IGF1R beta (Tyr980)

Classification:

Monoclonal

Concentration:

31.5 μg/mL

Formulation:

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:

P08069, P24062, Q60751

Gene Symbols:

IGF1R

Immunogen:

Synthetic phosphopeptide corresponding to residues surrounding pTyr980 of human IGF-I Receptor β

Quantity:

100 μL

Primary or Secondary:

Primary

Target Species:

Human, Mouse, Rat

Product Type:

Antibody

Isotype:

IgG

Applications:

Western Blot

Clone:

T.968.0

Conjugate:

Unconjugated

Gene:

IGF1R

Gene Alias:

A330103N21Rik; CD221; D930020L01; hyft; IGF1R; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2

Host Species:

Rabbit

Purification Method:

Affinity chromatography

Regulatory Status:

RUO

Gene ID (Entrez):

16001, 25718, 3480

Content And Storage:

-20°C

Form:

Liquid

Thermo Scientific

PIMA514861

Antigen:

AGO2

Classification:

Monoclonal

Concentration:

260 μg/mL

Formulation:

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:

Q8CJG0, Q9QZ81, Q9UKV8

Gene Symbols:

AGO2

Immunogen:

Synthetic peptide corresponding to mouse Argonaute 2

Quantity:

100 μL

Primary or Secondary:

Primary

Target Species:

Human, Mouse, Non-human Primate, Rat

Product Type:

Antibody

Isotype:

IgG

Applications:

Immunoprecipitation, Western Blot

Clone:

R.386.2

Conjugate:

Unconjugated

Gene:

AGO2

Gene Alias:

1110029L17Rik; 2310051F07Rik; AGO1; AGO2; AI225898; AL022874; argonaute 2; argonaute 2, RISC catalytic component; argonaute RISC catalytic component 2; argonaute RISC catalytic subunit 2; Argonaute1; argonaute2; argonaute2 {ECO:0000255; AW546247; CTA-204B4.6; eIF2C; eIF2C 1; eIF-2C 1; eIF2C 2; eIF-2C 2; eIF2C 2 {ECO:0000255; eIF-2C 2 {ECO:0000255; EIF2C1; Eif2c2; ENSMUSG00000072493; Eukaryotic translation initiation factor 2C 2; eukaryotic translation initiation factor 2C 2 {ECO:0000255; eukaryotic translation initiation factor 2C, 2; GERp95; Gm10365; Golgi ER protein 95 kDa; hAgo1; hAgo2; HAMAP-Rule:MF_03031}; Kiaa4215; mAgo2; mKIAA4215; PAZ Piwi domain protein; Piwi/Argonaute family protein meIF2C2; PPD; Protein argonaute-1; protein argonaute-2; Protein slicer; Q10

Host Species:

Rabbit

Purification Method:

Affinity chromatography

Regulatory Status:

RUO

Gene ID (Entrez):

239528, 27161, 59117

Content And Storage:

-20°C

Form:

Liquid

Phospho-IKK alpha/beta (Ser176, Ser177) Monoclonal Antibody (J.10.3), Invitrogen™

Select a Size

Select a Size

Properties

Antigen

Classification

Concentration

Formulation

Gene Accession No.

Gene Symbols

Immunogen

Quantity

Primary or Secondary

Target Species

Product Type

Isotype

Applications

Clone

Conjugate

Gene

Gene Alias

Host Species

Purification Method

Regulatory Status

Gene ID (Entrez)

Content And Storage

Form

Related Products

Thermo Scientific

Thermo Scientific

Thermo Scientific

Thermo Scientific

Thermo Scientific

Thermo Scientific

Thermo Scientific

Thermo Scientific

Description

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Show Difference

Thermo Scientific

Thermo Scientific

Thermo Scientific

Thermo Scientific