PIMA515087
Phospho-IkB alpha (Ser32) Monoclonal Antibody (B.142.7), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515087-Each-of-1 | In Stock | ₹ 52,106.04 |
PIMA515087 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,106.04
GST (18%): ₹ 9,379.087
Total Price: ₹ 61,485.127
Antigen
Phospho-IkB alpha (Ser32)
Classification
Monoclonal
Concentration
218.3 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
P25963, Q63746, Q9Z1E3
Gene Symbols
NFKBIA
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding pSer32 of human IkB alpha.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunoprecipitation, Western Blot
Clone
B.142.7
Conjugate
Unconjugated
Gene
NFKBIA
Gene Alias
AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18035, 25493, 4792
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity
- The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol
- The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus
- A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha
- These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses
- In humans, the gene is located on the q arm of chromosome 14
- Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB
- IkB kinase alpha (IKK alpha), previously designated CHUK, interacts with IkB-alpha and specifically phosphorylates IkB-alpha on the sites that trigger its degradation Serines 32 and 36
- IKK alpha appears to be critical for NFkB activation in response to proinflammatory cytokines
- Phosphorylation of IkB by IKK alpha is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1
- The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma, and each appear to make essential contributions to IkB phosphorylation.
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Antigen: Phospho-IkB alpha (Ser32)
Classification: Monoclonal
Concentration: 218.3 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P25963, Q63746, Q9Z1E3
Gene Symbols: NFKBIA
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding pSer32 of human IkB alpha.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Clone: B.142.7
Conjugate: Unconjugated
Gene: NFKBIA
Gene Alias: AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18035, 25493, 4792
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-IkB alpha (Ser32)
Classification:
Monoclonal
Concentration:
218.3 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P25963, Q63746, Q9Z1E3
Gene Symbols:
NFKBIA
Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer32 of human IkB alpha.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Clone:
B.142.7
Conjugate:
Unconjugated
Gene:
NFKBIA
Gene Alias:
AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18035, 25493, 4792
Content And Storage:
-20°C
Form:
Liquid
Antigen: AMPK beta-1,2
Classification: Monoclonal
Concentration: __
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: O43741, P80386, Q6PAM0, Q9QZH4, Q9R078, Q9Y478
Gene Symbols: Prkab1, PRKAB2
Immunogen: Synthetic peptide corresponding to the sequence surrounding His233 residues of human AMPKβ1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Hamster, Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: E.427.6
Conjugate: Unconjugated
Gene: PRKAB2
Gene Alias: 1300015D22Rik; 5730553K21Rik; 5'-AMP-activated protein kinase 40 kDa subunit; 5-AMP-activated protein kinase beta subunit; 5'-AMP-activated protein kinase beta-1 subunit; 5'-AMP-activated protein kinase subunit beta-1; 5'-AMP-activated protein kinase subunit beta-1-like protein; 5'-AMP-activated protein kinase subunit beta-2; 5'-AMP-activated protein kinase, beta subunit; 5'-AMP-activated protein kinase, beta-2 subunit; AMP-activated protein kinase beta 2 non-catalytic subunit; AMP-activated protein kinase beta subunit; AMP-activated protein kinase beta-2 regulatory subunit; AMPK; AMPK beta 1; AMPK beta -1 chain; AMPK beta 2; AMPK beta-1 chain; AMPK beta-2 chain; AMPK subunit beta-1; AMPK subunit beta-2; AMPKb; AU021155; AW049591; BB124140; E430008F22; HAMPKb; I79_012592; PRKAB1; Prkab2; protein kinase AMP-activated non-catalytic subunit beta 1; protein kinase AMP-activated non-catalytic subunit beta 2; protein kinase, AMP-activated, beta 1 non-catalytic subunit; protein kinase, AMP-activated, beta 2 non-catalytic subunit; protein kinase, AMP-activated, noncatalytic, beta-1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100755226, 100772359, 108097, 19079, 5564, 5565, 64562, 83803
Content And Storage: -20°C
Form: Liquid
Antigen:
AMPK beta-1,2
Classification:
Monoclonal
Concentration:
__
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
O43741, P80386, Q6PAM0, Q9QZH4, Q9R078, Q9Y478
Gene Symbols:
Prkab1, PRKAB2
Immunogen:
Synthetic peptide corresponding to the sequence surrounding His233 residues of human AMPKβ1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Hamster, Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
E.427.6
Conjugate:
Unconjugated
Gene:
PRKAB2
Gene Alias:
1300015D22Rik; 5730553K21Rik; 5'-AMP-activated protein kinase 40 kDa subunit; 5-AMP-activated protein kinase beta subunit; 5'-AMP-activated protein kinase beta-1 subunit; 5'-AMP-activated protein kinase subunit beta-1; 5'-AMP-activated protein kinase subunit beta-1-like protein; 5'-AMP-activated protein kinase subunit beta-2; 5'-AMP-activated protein kinase, beta subunit; 5'-AMP-activated protein kinase, beta-2 subunit; AMP-activated protein kinase beta 2 non-catalytic subunit; AMP-activated protein kinase beta subunit; AMP-activated protein kinase beta-2 regulatory subunit; AMPK; AMPK beta 1; AMPK beta -1 chain; AMPK beta 2; AMPK beta-1 chain; AMPK beta-2 chain; AMPK subunit beta-1; AMPK subunit beta-2; AMPKb; AU021155; AW049591; BB124140; E430008F22; HAMPKb; I79_012592; PRKAB1; Prkab2; protein kinase AMP-activated non-catalytic subunit beta 1; protein kinase AMP-activated non-catalytic subunit beta 2; protein kinase, AMP-activated, beta 1 non-catalytic subunit; protein kinase, AMP-activated, beta 2 non-catalytic subunit; protein kinase, AMP-activated, noncatalytic, beta-1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100755226, 100772359, 108097, 19079, 5564, 5565, 64562, 83803
Content And Storage:
-20°C
Form:
Liquid
Antigen: JNK3
Classification: Monoclonal
Concentration: __
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P49187, P53779, Q61831
Gene Symbols: MAPK10
Immunogen: Synthetic peptide corresponding to human JNK3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: K.238.3
Conjugate: Unconjugated
Gene: MAPK10
Gene Alias: C230008H04Rik; c-Jun N-terminal kinase 3; hypothetical protein LOC569698; jnk3; JNK3 alpha protein kinase; JNK3 beta1 protein kinase; JNK3 beta2 protein kinase; JNK3A; JNK3B1; JNK3B2; MAP kinase 10; MAP kinase p49 3F12; MAPK 10; MAPK10; mitogen activated protein kinase 10; mitogen-activated protein kinase 10; OTTHUMP00000161181; OTTHUMP00000161183; OTTHUMP00000218718; p493F12; p54-beta; p54bSAPK; PRKM10; SAPb; SAPK(beta); SAPK/Erk/kinase 2; SAPK1B; SAPK-beta; SAPKC; Serk2; Stress activated protein kinase beta; stress-activated protein kinase 1b; Stress-activated protein kinase JNK3; zgc:123234
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 25272, 26414, 5602
Content And Storage: -20°C
Form: Liquid
Antigen:
JNK3
Classification:
Monoclonal
Concentration:
__
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P49187, P53779, Q61831
Gene Symbols:
MAPK10
Immunogen:
Synthetic peptide corresponding to human JNK3
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
K.238.3
Conjugate:
Unconjugated
Gene:
MAPK10
Gene Alias:
C230008H04Rik; c-Jun N-terminal kinase 3; hypothetical protein LOC569698; jnk3; JNK3 alpha protein kinase; JNK3 beta1 protein kinase; JNK3 beta2 protein kinase; JNK3A; JNK3B1; JNK3B2; MAP kinase 10; MAP kinase p49 3F12; MAPK 10; MAPK10; mitogen activated protein kinase 10; mitogen-activated protein kinase 10; OTTHUMP00000161181; OTTHUMP00000161183; OTTHUMP00000218718; p493F12; p54-beta; p54bSAPK; PRKM10; SAPb; SAPK(beta); SAPK/Erk/kinase 2; SAPK1B; SAPK-beta; SAPKC; Serk2; Stress activated protein kinase beta; stress-activated protein kinase 1b; Stress-activated protein kinase JNK3; zgc:123234
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
25272, 26414, 5602
Content And Storage:
-20°C
Form:
Liquid
Antigen: MEK1
Classification: Monoclonal
Concentration: 227 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P31938, Q01986, Q02750
Gene Symbols: Map2k1
Immunogen: Full length MEK1 proteins
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG2a
Applications: Immunoprecipitation, Western Blot
Clone: K.971.4
Conjugate: Unconjugated
Gene: Map2k1
Gene Alias: CFC3; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; Map2k1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 170851, 26395, 5604
Content And Storage: -20°C
Form: Liquid
Antigen:
MEK1
Classification:
Monoclonal
Concentration:
227 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P31938, Q01986, Q02750
Gene Symbols:
Map2k1
Immunogen:
Full length MEK1 proteins
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunoprecipitation, Western Blot
Clone:
K.971.4
Conjugate:
Unconjugated
Gene:
Map2k1
Gene Alias:
CFC3; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; Map2k1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
170851, 26395, 5604
Content And Storage:
-20°C
Form:
Liquid