PIMA515860

NFkB p50 Monoclonal Antibody (5D10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515860-Each-of-1 In Stock ₹ 53,047.20

PIMA515860 - Each of 1

₹ 53,047.20

In Stock

Quantity

1

Base Price: ₹ 53,047.20

GST (18%): ₹ 9,548.496

Total Price: ₹ 62,595.696

Antigen

NFkB p50

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

P19838

Gene Symbols

NFKB1

Immunogen

Purified recombinant fragment of human NFKB1 expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

4790

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunohistochemistry, Western Blot

Clone

5D10

Conjugate

Unconjugated

Gene

NFKB1

Gene Alias

CVID12; DKFZp686C01211; DNA-binding factor KBF1; EBP-1; KBF1; MGC54151; NF kappaB1; NF KB; NFkappaB; NF-kappaB; NF-kappa-B; NF-kappaB p50; NF-kappaB1; NF-kappa-B1 p84/NF-kappa-B1 p98; NF-kappabeta; NF-kB; NFKB1; NF-kB1; NFKB-p105; NFKB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit 1; nuclear factor kappa-B 1; nuclear factor kappa-B DNA binding subunit; nuclear factor kappaB p50; nuclear factor NF-kappa-B p105 subunit; nuclear factor NF-kappa-B p105 subunit-like protein; nuclear factor NF-kappa-B p50 subunit; nuclear factor of kappa light chain gene enhancer in B-cells 1, p105; nuclear factor of kappa light polypeptide enhancer in B-cells 1; nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105); nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105; nuclear factor-kappaB

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • MA5-15860 targets NFKB1 in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with Human samples
  • The MA5-15860 immunogen is purified recombinant fragment of human NFKB1 expressed in E
  • Coli
  • MA5-15860 detects NFKB1 which has a predicted molecular weight of approximately 50kDa/105kDa
  • NFkB is a nuclear transcription factor activated by various extra and intracellular stimuli such as cytokines, UV radiation, stress, in injury, and by bacterial and viral products
  • NFkB is involved in regulation of various cellular events including cell growth, differentiation, proliferation, apoptosis and inflammation
  • NFKB1 (p50) is a 50KDa functional sub-unit of NF-kB and a member of Rel protein family which is synthesized as a p105 precursor protein and consists of an N-terminal conserved RHD-region containing nuclear localization signal, DNA-binding and dimerization domains
  • NFKB1 (p50) forms homodimers or heterodimerizes with p65, forming the functional NFkB factor
  • Further, NFKB1 (p50) directs the nuclear translocation of NF-kB and is instrumental in its DNA-binding
  • The NFkB complex is expressed in most cell types, and is primarily found in the cytoplasm in an inactive state in association with I-kappa-B
  • Phosphorylation of I-kappa-B releases the complex, allowing translocation to the nucleus and modification of gene expression
  • Phosphorylation of the p50 subunit at the Ser-337 residue has been shown to significantly increase DNA binding efficiency of the NFkB protein complex
  • The pathological role of NFkB has been suggested in AIDS, hematogenic cancer cell metastasis and rheumatoid arthritis.

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Thermo Scientific

PIMA515860

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Antigen:
NFkB p50

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P19838

Gene Symbols:
NFKB1

Immunogen:
Purified recombinant fragment of human NFKB1 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
4790

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunohistochemistry, Western Blot

Clone:
5D10

Conjugate:
Unconjugated

Gene:
NFKB1

Gene Alias:
CVID12; DKFZp686C01211; DNA-binding factor KBF1; EBP-1; KBF1; MGC54151; NF kappaB1; NF KB; NFkappaB; NF-kappaB; NF-kappa-B; NF-kappaB p50; NF-kappaB1; NF-kappa-B1 p84/NF-kappa-B1 p98; NF-kappabeta; NF-kB; NFKB1; NF-kB1; NFKB-p105; NFKB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit 1; nuclear factor kappa-B 1; nuclear factor kappa-B DNA binding subunit; nuclear factor kappaB p50; nuclear factor NF-kappa-B p105 subunit; nuclear factor NF-kappa-B p105 subunit-like protein; nuclear factor NF-kappa-B p50 subunit; nuclear factor of kappa light chain gene enhancer in B-cells 1, p105; nuclear factor of kappa light polypeptide enhancer in B-cells 1; nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105); nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105; nuclear factor-kappaB

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

Thermo Scientific

PIMA515861

--


Antigen:
ASK1

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
Q99683

Gene Symbols:
MAP3K5

Immunogen:
Purified recombinant fragment of human MAP3K5 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
4217

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
2E4

Conjugate:
Unconjugated

Gene:
MAP3K5

Gene Alias:
7420452D20Rik; apoptosis signal regulating kinase 1; apoptosis signal-regulating kinase 1; ASK; ASK 1; ASK1; ASK-1; EC 2.7.11.25; kinase ASK1; M3K5; MAP/ERK kinase kinase 5; Map3k5; MAPK/ERK kinase kinase 5; MAPKKK5; MEK kinase 5; MEKK 5; Mekk5; mitogen activated protein kinase kinase kinase 5; mitogen-activated protein kinase kinase kinase 5; RGD1306565; RP3-325F22.4

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515863

--


Antigen:
HSP90 beta

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P08238, P11499, P34058

Gene Symbols:
Hsp90ab1

Immunogen:
Purified recombinant fragment of human HSP90AB1 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
15516, 301252, 3326

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
5G4D2

Conjugate:
Unconjugated

Gene:
Hsp90ab1

Gene Alias:
90kDa; 90-kDa heat shock protein beta; AL022974; C81438; D6S182; heat shock 84 kDa; heat shock 90 kDa protein; heat shock 90kD protein 1, beta; heat shock 90kDa protein 1, beta; heat shock cognate protein HSP 90-beta; Heat shock protein; heat shock protein 1, beta; heat shock protein 90 alpha (cytosolic), class B member 1; heat shock protein 90 alpha family class B member 1; heat shock protein 90 beta; heat shock protein 90 kDa; heat shock protein 90 kDa alpha class B member 1; heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock protein 90kDa alpha family class B member 1; Heat shock protein HSP 90-beta; heat shock protein, 84 kDa 1; HSP; HSP 84; HSP 90; Hsp84; Hsp84-1; Hsp90; hsp90 beta; HSP90AB1; HSP90B; HSP90-beta; HSPC2; HSPCB; retinal degeneration slow protein; RP1-302G2.1; TSTA; Tumor-specific transplantation 84 kDa antigen; Unknown (protein for IMAGE:7943063)

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515864

--


Antigen:
HSP90 beta

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P08238, P11499, P34058

Gene Symbols:
Hsp90ab1

Immunogen:
Purified recombinant fragment of human HSP90AB1 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
15516, 301252, 3326

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
1D9

Conjugate:
Unconjugated

Gene:
Hsp90ab1

Gene Alias:
90kDa; 90-kDa heat shock protein beta; AL022974; C81438; D6S182; heat shock 84 kDa; heat shock 90 kDa protein; heat shock 90kD protein 1, beta; heat shock 90kDa protein 1, beta; heat shock cognate protein HSP 90-beta; Heat shock protein; heat shock protein 1, beta; heat shock protein 90 alpha (cytosolic), class B member 1; heat shock protein 90 alpha family class B member 1; heat shock protein 90 beta; heat shock protein 90 kDa; heat shock protein 90 kDa alpha class B member 1; heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock protein 90kDa alpha family class B member 1; Heat shock protein HSP 90-beta; heat shock protein, 84 kDa 1; HSP; HSP 84; HSP 90; Hsp84; Hsp84-1; Hsp90; hsp90 beta; HSP90AB1; HSP90B; HSP90-beta; HSPC2; HSPCB; retinal degeneration slow protein; RP1-302G2.1; TSTA; Tumor-specific transplantation 84 kDa antigen; Unknown (protein for IMAGE:7943063)

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1