PIMA515320

IKK beta Monoclonal Antibody (10A2C5B3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515320-Each-of-1 In Stock ₹ 48,127.50

PIMA515320 - Each of 1

₹ 48,127.50

In Stock

Quantity

1

Base Price: ₹ 48,127.50

GST (18%): ₹ 8,662.95

Total Price: ₹ 56,790.45

Antigen

IKK beta

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

O14920

Gene Symbols

Ikbkb

Immunogen

Purified recombinant fragment of IKBKB expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

3551

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunohistochemistry, Western Blot

Clone

10A2C5B3

Conjugate

Unconjugated

Gene

Ikbkb

Gene Alias

AI132552; AIM-1; FLJ40509; I-kappa-B kinase 2; I-kappa-B-kinase beta; Ikbkb; IKK[b]; IKK2; IKK-2; IKKB; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; nuclear factor NF-kappa-B inhibitor kinase beta

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15320 targets IKBKB in indirect ELISA, IHC and WB applications and shows reactivity with Human samples
  • The MA5-15320 immunogen is purified recombinant fragment of IKBKB expressed in E
  • Coli
  • Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex
  • Inhibitor of nuclear factor kappa-B kinase subunit beta (IKK beta) is a serine kinase that plays an essential role in the NF-kaapa-B signaling pathway which is activated by mulitple stimuli such as inflammatory cytokines, bacterial, or viral products, DNA damages, or other cellular stresses
  • IKK beta acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues
  • These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome
  • In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis
  • Mutations affecting the IKK beta gene can result in Immunodeficiency 15 (IMD15).

Compare Similar Items

Show Difference

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Thermo Scientific

PIMA515320

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Antigen:
IKK beta

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
O14920

Gene Symbols:
Ikbkb

Immunogen:
Purified recombinant fragment of IKBKB expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
3551

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
10A2C5B3

Conjugate:
Unconjugated

Gene:
Ikbkb

Gene Alias:
AI132552; AIM-1; FLJ40509; I-kappa-B kinase 2; I-kappa-B-kinase beta; Ikbkb; IKK[b]; IKK2; IKK-2; IKKB; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; nuclear factor NF-kappa-B inhibitor kinase beta

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

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PIMA515323

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Antigen:
Apolipoprotein M

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.03% sodium azide

Gene Accession No.:
O95445

Gene Symbols:
APOM

Immunogen:
Purified recombinant fragment of ApoM expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
55937

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
10C3G5

Conjugate:
Unconjugated

Gene:
APOM

Gene Alias:
1190010O19Rik; alternative name: G3a, NG20; Apo M; Apolipoprotein M; APOM; apo-M; G3A; HSPC336; MGC22400; NG20; NG20 like protein; NG20-like protein; protein G3a; Protein Px

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG2a

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PIMA515326

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Antigen:
S100A10

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P60903

Gene Symbols:
S100A10

Immunogen:
Purified recombinant fragment of human P11 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
6281

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
4E7E10

Conjugate:
Unconjugated

Gene:
S100A10

Gene Alias:
42C; AA409961; AL024248; Annexin II; annexin II ligand; annexin II ligand, calpactin I, light polypeptide; annexin II tetramer (AIIt) p11 subunit; ANX2L; ANX2LG; Ca[1]; CAL12; Cal1l; calcium binding protein A11 (calgizzarin); calpactin I light chain; Calpactin-1 light chain; cellular ligand of annexin II; CLP11; GP11; MGC111133; MGC133268; Nerve growth factor-induced protein 42C; OTTHUMP00000015270; P PRSS26; p10; p10 protein; P11; p11 subunit; Protein S100 A10; Protein S100-A10; S100 calcium binding protein A10; S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); S100 calcium binding protein A10 (calgizzarin); S100 calcium binding protein A10 (calpactin); S100 calcium-binding protein A10; S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); S-100 related protein, clone 42C; S100a10

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515327

--


Antigen:
c-Kit

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P10721

Gene Symbols:
KIT

Immunogen:
Purified recombinant fragment of C-kit expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
3815

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
8D7

Conjugate:
Unconjugated

Gene:
KIT

Gene Alias:
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1