PIMA515327
c-Kit Monoclonal Antibody (8D7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515327-Each-of-1 | In Stock | ₹ 48,127.50 |
PIMA515327 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,127.50
GST (18%): ₹ 8,662.95
Total Price: ₹ 56,790.45
Antigen
c-Kit
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P10721
Gene Symbols
KIT
Immunogen
Purified recombinant fragment of C-kit expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
3815
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunohistochemistry, Western Blot
Clone
8D7
Conjugate
Unconjugated
Gene
KIT
Gene Alias
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15327 targets C-Kit in indirect ELISA, IHC and WB applications and shows reactivity with Human samples
- The MA5-15327 immunogen is purified recombinant fragment of C-kit expressed in E
- Coli
- MA5-15327 detects C-Kit which has a predicted molecular weight of approximately 145kDa
- KIT (c-KIT) is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor)
- KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit
- KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells
- Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism
- Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth
- c-Kit is expressed in hematopoietic stem cells, germ cells, mast cells and gastrointestinal tract cajal cells
- Upon binding of its ligand stem cell factor (SCF), c-kit dimerizes, resulting in receptor activation and autophosphorylation of various tyrosine residues including tyrosine 703 located on the cytoplasmic domain of the receptor
- This modification allows docking of Grb2 and activation of the Ras/ERK signaling pathway
- SCF/c-kit can activate multiple downstream signaling pathways including PI3K, PLC-gamma and JAK/STAT
- c-kit receptor activation is essential for hematopoiesis, stem cell maintenance and gametogenesis.
Compare Similar Items
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Antigen: c-Kit
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: P10721
Gene Symbols: KIT
Immunogen: Purified recombinant fragment of C-kit expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 3815
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunohistochemistry, Western Blot
Clone: 8D7
Conjugate: Unconjugated
Gene: KIT
Gene Alias: belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
c-Kit
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
P10721
Gene Symbols:
KIT
Immunogen:
Purified recombinant fragment of C-kit expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
3815
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Western Blot
Clone:
8D7
Conjugate:
Unconjugated
Gene:
KIT
Gene Alias:
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: BRK
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: Q13882
Gene Symbols: PTK6
Immunogen: Purified recombinant fragment of human PTK6 expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 5753
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Western Blot
Clone: 2H12B8
Conjugate: Unconjugated
Gene: PTK6
Gene Alias: ALT-PTK6; breast tumor kinase; BRK; deltam5; FLJ42088; protein tyrosine kinase 6; protein-tyrosine kinase 6; protein-tyrosine kinase BRK; Ptk6; PTK6 protein tyrosine kinase 6; Sik; SRC-related intestinal kinase; tks; Tksk; tyrosine kinase identified from skin; tyrosine-protein kinase BRK
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Antigen:
BRK
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
Q13882
Gene Symbols:
PTK6
Immunogen:
Purified recombinant fragment of human PTK6 expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
5753
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Western Blot
Clone:
2H12B8
Conjugate:
Unconjugated
Gene:
PTK6
Gene Alias:
ALT-PTK6; breast tumor kinase; BRK; deltam5; FLJ42088; protein tyrosine kinase 6; protein-tyrosine kinase 6; protein-tyrosine kinase BRK; Ptk6; PTK6 protein tyrosine kinase 6; Sik; SRC-related intestinal kinase; tks; Tksk; tyrosine kinase identified from skin; tyrosine-protein kinase BRK
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Antigen: Lyn
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: P07948
Gene Symbols: LYN
Immunogen: Purified recombinant fragment of LYN expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 4067
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunocytochemistry, Western Blot
Clone: 2H8D7
Conjugate: Unconjugated
Gene: LYN
Gene Alias: AA407514; CD180; CD180 antigen; CD180 molecule; CH73-38P6.3; FLJ26625; Hck-2; JTK8; lck/Yes-related novel protein tyrosine kinase; LY64; Ly78; lymphocyte antigen 64; lymphocyte antigen-64, radioprotective, 105kDa; LYN; lyn protein non-receptor kinase; lyn protein tyrosine kinase; LYN proto-oncogene, Src family tyrosine kinase; p53Lyn; p56Lyn; Radioprotective 105 kDa protein; RP105; Tyrosine-protein kinase Lyn; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; v-yes-1 Yamaguchi sarcoma viral related oncogene protein-like protein; Yamaguchi sarcoma viral (v-yes-1) oncogene homolog; zgc:92124
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Antigen:
Lyn
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
P07948
Gene Symbols:
LYN
Immunogen:
Purified recombinant fragment of LYN expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
4067
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Western Blot
Clone:
2H8D7
Conjugate:
Unconjugated
Gene:
LYN
Gene Alias:
AA407514; CD180; CD180 antigen; CD180 molecule; CH73-38P6.3; FLJ26625; Hck-2; JTK8; lck/Yes-related novel protein tyrosine kinase; LY64; Ly78; lymphocyte antigen 64; lymphocyte antigen-64, radioprotective, 105kDa; LYN; lyn protein non-receptor kinase; lyn protein tyrosine kinase; LYN proto-oncogene, Src family tyrosine kinase; p53Lyn; p56Lyn; Radioprotective 105 kDa protein; RP105; Tyrosine-protein kinase Lyn; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; v-yes-1 Yamaguchi sarcoma viral related oncogene protein-like protein; Yamaguchi sarcoma viral (v-yes-1) oncogene homolog; zgc:92124
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Antigen: Abl2
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites with 0.03% sodium azide
Gene Accession No.: P42684
Gene Symbols: ABL2
Immunogen: Purified recombinant fragment of ABL2 expressed in E. Coli.
Regulatory Status: RUO
Gene ID (Entrez): 27
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Immunocytochemistry, Western Blot
Clone: 1H1B11
Conjugate: Unconjugated
Gene: ABL2
Gene Alias: AA536808; Abelson murine leukemia viral (v-abl) oncogene homolog 2; abelson murine leukemia viral oncogene homolog 2; Abelson tyrosine-protein kinase 2; Abelson-related gene protein; ABL proto-oncogene 2, non-receptor tyrosine kinase; Abl1-related gene product; abl2; ABLL; ARG; arg tyrosine kinase; c-abl oncogene 2, non-receptor tyrosine kinase; FLJ22224; FLJ31718; FLJ41441; tyrosine kinase ARG; tyrosine-protein kinase ABL2; Tyrosine-protein kinase ARG; v-abl Abelson murine leukemia viral oncogene 2; v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene); v-abl Abelson murine leukemia viral oncogene homolog 2; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
Abl2
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
ascites with 0.03% sodium azide
Gene Accession No.:
P42684
Gene Symbols:
ABL2
Immunogen:
Purified recombinant fragment of ABL2 expressed in E. Coli.
Regulatory Status:
RUO
Gene ID (Entrez):
27
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Western Blot
Clone:
1H1B11
Conjugate:
Unconjugated
Gene:
ABL2
Gene Alias:
AA536808; Abelson murine leukemia viral (v-abl) oncogene homolog 2; abelson murine leukemia viral oncogene homolog 2; Abelson tyrosine-protein kinase 2; Abelson-related gene protein; ABL proto-oncogene 2, non-receptor tyrosine kinase; Abl1-related gene product; abl2; ABLL; ARG; arg tyrosine kinase; c-abl oncogene 2, non-receptor tyrosine kinase; FLJ22224; FLJ31718; FLJ41441; tyrosine kinase ARG; tyrosine-protein kinase ABL2; Tyrosine-protein kinase ARG; v-abl Abelson murine leukemia viral oncogene 2; v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene); v-abl Abelson murine leukemia viral oncogene homolog 2; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)
Host Species:
Mouse
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1