PIMA515398

SRC Monoclonal Antibody (4F1E8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515398-Each-of-1 In Stock ₹ 48,127.50

PIMA515398 - Each of 1

₹ 48,127.50

In Stock

Quantity

1

Base Price: ₹ 48,127.50

GST (18%): ₹ 8,662.95

Total Price: ₹ 56,790.45

Antigen

SRC

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

P12931

Gene Symbols

SRC

Immunogen

Purified recombinant fragment of SRC (aa10-193) expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

6714

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Western Blot

Clone

4F1E8

Conjugate

Unconjugated

Gene

SRC

Gene Alias

ASV; AW259666; csrc; c-SRC; c-src protein, C terminus; EC 2.7.10.2; fc54g04; Neuronal proto-oncogene tyrosine-protein kinase Src; non-tyrosine protein kinase; ORF; OTTHUMP00000174476; OTTHUMP00000174477; OTTHUMP00000174478; p60-Src; p60-Src-1; PP60C-SCR; pp60c-src; pp60src; pp60v-src; protein-tyrosine kinase; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; Proto-oncogene tyrosine-protein kinase Src; Rous sarcoma oncogene; RP5-823N20.1; sb:cb864; SDR; src; src downstream region; src oncogene; SRC proto-oncogene, non-receptor tyrosine kinase; SRC proto-oncogene, non-receptor tyrosine kinase L homeolog; SRC proto-oncogene, non-receptor tyrosine kinase S homeolog; src.L; src.S; SRC1; src-1; src1-A; src-a; src-b; THC6; transforming protein; tyrosine kinase pp60c-src; tyrosine protein kinase c-src; tyrosine protein kinase pp60-c-src; tyrosine-protein kinase SRC-1; Unknown; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogen

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • MA5-15398 targets SRC in indirect ELISA, WB applications and shows reactivity with Human samples
  • The MA5-15398 immunogen is purified recombinant fragment of SRC (aa10-193) expressed in E
  • Coli
  • SRC is a cytoplasmic tyrosine kinase and proto-oncogene involved in the regulation of embryonic development and cell growth
  • SRC is involved in the regulation of growth and differentiation of eukaryotic cells
  • SRC associates with the cytoplasmic region of various cell surface receptors to facilitate signal transduction, and is also involved in cytoskeletal organization, cell cycle regulation, and apoptosis
  • In humans, the gene encoding SRC is present on chromosome 20
  • Activity of SRC is regulated by two tyrosine residues (Tyr 416 and Tyr527), and phosphorylation of these two sites have opposing effects
  • Phosphorylation of Tyr416 in the activation loop of the kinase domain upregulates enzyme activity while the phosphorylation of Tyr527 decreases enzyme activity
  • Mutations in the SRC gene could be involved in the malignant progression of colon cancer
  • Two transcript variants encoding the same SRC protein have been found thus far.

Compare Similar Items

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Img

Thermo Scientific

PIMA515398

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Antigen:
SRC

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P12931

Gene Symbols:
SRC

Immunogen:
Purified recombinant fragment of SRC (aa10-193) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
6714

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
4F1E8

Conjugate:
Unconjugated

Gene:
SRC

Gene Alias:
ASV; AW259666; csrc; c-SRC; c-src protein, C terminus; EC 2.7.10.2; fc54g04; Neuronal proto-oncogene tyrosine-protein kinase Src; non-tyrosine protein kinase; ORF; OTTHUMP00000174476; OTTHUMP00000174477; OTTHUMP00000174478; p60-Src; p60-Src-1; PP60C-SCR; pp60c-src; pp60src; pp60v-src; protein-tyrosine kinase; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; Proto-oncogene tyrosine-protein kinase Src; Rous sarcoma oncogene; RP5-823N20.1; sb:cb864; SDR; src; src downstream region; src oncogene; SRC proto-oncogene, non-receptor tyrosine kinase; SRC proto-oncogene, non-receptor tyrosine kinase L homeolog; SRC proto-oncogene, non-receptor tyrosine kinase S homeolog; src.L; src.S; SRC1; src-1; src1-A; src-a; src-b; THC6; transforming protein; tyrosine kinase pp60c-src; tyrosine protein kinase c-src; tyrosine protein kinase pp60-c-src; tyrosine-protein kinase SRC-1; Unknown; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogen

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

Thermo Scientific

PIMA515400

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Antigen:
IGFBP2

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P18065

Gene Symbols:
IGFBP2

Immunogen:
Purified recombinant fragment of protein IGFBP2 (aa180-328) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
3485

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
1F6F6

Conjugate:
Unconjugated

Gene:
IGFBP2

Gene Alias:
AI255832; BP2; BRL-BP; IBP2; IBP-2; IGF binding protein 2; IGF-binding protein 2; IGFBP; IGFBP2; IGFBP-2; IGF-BP53; ILGFBPA; Insulin like growth factor binding protein; insulin like growth factor binding protein 2; insulin-like growth factor binding protein 2; insulin-like growth factor binding protein 2, 36kDa; insulin-like growth factor-binding protein 2; mIGFBP-2; OTTHUMP00000207753

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

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PIMA515401

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Antigen:
Progesterone Receptor

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P06401

Gene Symbols:
PGR

Immunogen:
Purified recombinant fragment of PGR (aa731-909) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
5241

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
2C11F11

Conjugate:
Unconjugated

Gene:
PGR

Gene Alias:
9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

Thermo Scientific

PIMA515408

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Antigen:
PAR4

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
Q96IZ0

Gene Symbols:
Pawr

Immunogen:
Purified recombinant fragment of PAR4(aa1-330) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
5074

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
3G9H7,4H12E9, 4H12E9

Conjugate:
Unconjugated

Gene:
Pawr

Gene Alias:
2310001G03Rik; coagulation factor II (thrombin) receptor-like 3; Coagulation factor II receptor-like 3; F2R like thrombin/trypsin receptor 3; F2RL3; PAR4; Par-4; par-4 induced by effectors of apoptosis; Pawr; PRKC apoptosis WT1 regulator protein; PRKC, apoptosis, WT1, regulator; pro-apoptotic WT1 regulator; prostate apoptosis response 4; prostate apoptosis response 4 protein; Prostate apoptosis response protein 4; prostate apoptosis response protein PAR-4; prostate apoptosis response-4; protease-activated receptor-4; proteinase-activated receptor 4; Thrombin receptor-like 3; transcriptional repressor PAR4; transcriptional repressor Par-4-like protein PAWR; WT1-interacting protein

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1