PIMA515093

MEK1 Monoclonal Antibody (K.971.4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515093-Each-of-1 In Stock ₹ 42,651.66

PIMA515093 - Each of 1

₹ 42,651.66

In Stock

Quantity

1

Base Price: ₹ 42,651.66

GST (18%): ₹ 7,677.299

Total Price: ₹ 50,328.959

Antigen

MEK1

Classification

Monoclonal

Concentration

227 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P31938, Q01986, Q02750

Gene Symbols

Map2k1

Immunogen

Full length MEK1 proteins

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG2a

Applications

Immunoprecipitation, Western Blot

Clone

K.971.4

Conjugate

Unconjugated

Gene

Map2k1

Gene Alias

CFC3; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; Map2k1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

170851, 26395, 5604

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • This antibody is not cross-reactive with MEK2 and other MAP kinase kinases
  • MAP2K1 (MEK1) kinase is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation
  • MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx
  • Mek1 is activated by phosphorylation of serine 218 and 222 residues by Raf1
  • It is known to be involved in the signaling during stress activate response, apoptosis and proliferative induction by cytokines
  • Mutations in the gene can lead to cardiofaciocutaneous syndrome.

Compare Similar Items

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Img

Thermo Scientific

PIMA515093

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Antigen:
MEK1

Classification:
Monoclonal

Concentration:
227 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P31938, Q01986, Q02750

Gene Symbols:
Map2k1

Immunogen:
Full length MEK1 proteins

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunoprecipitation, Western Blot

Clone:
K.971.4

Conjugate:
Unconjugated

Gene:
Map2k1

Gene Alias:
CFC3; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; Map2k1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170851, 26395, 5604

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515095

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Antigen:
Phospho-ZAP70/Syk (Tyr319, Tyr352)

Classification:
Monoclonal

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P43403, P43404

Gene Symbols:
LOC100739325, LOC100767740, ZAP70

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr319 of human Zap-70

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Chicken, Equine, Hamster, Human, Mouse, Non-human Primate, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
R.658.6

Conjugate:
Unconjugated

Gene:
ZAP70

Gene Alias:
70 kDa zeta-associated protein; 70 kDa zeta-chain associated protein; ADMIO2; EC 2.7.10.2; FLJ17670; FLJ17679; I79_004087; IMD48; kinase ZAP70; mrtle; mur; Selective T cell defect; Srk; STCD; STD; syk-related protein tyrosine kinase; syk-related tyrosine kinase; Tyrosine-protein kinase ZAP-70; Tyrosine-protein kinase ZAP-70;TZK; TZK; ZA70; Zap70; ZAP-70; Zeta chain associated protein kinase 70kDa; zeta chain of T cell receptor associated protein kinase; zeta chain of T cell receptor associated protein kinase 70; zeta chain of T cell receptor associated protein kinase 70kDa; zeta-chain (TCR) associated protein kinase; zeta-chain (TCR) associated protein kinase 70; zeta-chain (TCR) associated protein kinase 70kDa; zeta-chain associated protein kinase 70kDa; zeta-chain associated protein kinase, 70kD

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100147296, 100271860, 100739325, 100767740, 22637, 301348, 420086, 504509, 7535

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515098

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Antigen:
Phospho-c-Abl (Tyr245)

Classification:
Monoclonal

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P00519, P00520

Gene Symbols:
ABL1

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr245 of human c-Abl

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
S.44.4

Conjugate:
Unconjugated

Gene:
ABL1

Gene Alias:
Abelson murine leukemia oncogene; Abelson murine leukemia viral (v-abl) oncogene homolog 1; abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Abl; Abl 1 antib; ABL proto-oncogene 1, non-receptor tyrosine kinase; Abl1; ABL2; ABLL; AI325092; ARG; B30; bcr/abl; bcr/c-abl oncogene protein; c-ABL; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-ABL1; E430008G22Rik; JTK7; p150; Proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; RP11-83J21.1; Tyrosine kinase ARG; tyrosine-protein kinase ABL1; v-abl; v-abl Abelson murine leukemia oncogene 1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene homolog 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11350, 25

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515101

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Antigen:
EZH2

Classification:
Monoclonal

Concentration:
403 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
Q15910, Q61188

Gene Symbols:
EZH2

Immunogen:
Ezh2 recombinant protein containing human Ezh2 residues 351-453

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
H.547.3

Conjugate:
Unconjugated

Gene:
EZH2

Gene Alias:
an; enhancer of zeste 2 polycomb repressive complex 2 subunit; enhancer of zeste homolog 2; enhancer of zeste homolog 2 (Drosophila); ENX 1; ENX1; Enx-1; Enx1h; EZH 2; EZH1; EZH2; EZH-2; EZH2b; histone-lysine N-methyltransferase EZH2; KMT6; KMT6A; lysine N-methyltransferase 6; mKIAA4065; OTTHUMP00000213774; OTTHUMP00000213778; OTTHUMP00000213779; OTTHUMP00000213780; WVS; WVS2

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14056, 2146, 312299

Content And Storage:
-20°C

Form:
Liquid