PIMA515095

Phospho-ZAP70/Syk (Tyr319, Tyr352) Monoclonal Antibody (R.658.6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515095-Each-of-1 In Stock ₹ 46,159.62

PIMA515095 - Each of 1

₹ 46,159.62

In Stock

Quantity

1

Base Price: ₹ 46,159.62

GST (18%): ₹ 8,308.732

Total Price: ₹ 54,468.352

Antigen

Phospho-ZAP70/Syk (Tyr319, Tyr352)

Classification

Monoclonal

Conjugate

Unconjugated

Gene

ZAP70

Gene Alias

70 kDa zeta-associated protein; 70 kDa zeta-chain associated protein; ADMIO2; EC 2.7.10.2; FLJ17670; FLJ17679; I79_004087; IMD48; kinase ZAP70; mrtle; mur; Selective T cell defect; Srk; STCD; STD; syk-related protein tyrosine kinase; syk-related tyrosine kinase; Tyrosine-protein kinase ZAP-70; Tyrosine-protein kinase ZAP-70;TZK; TZK; ZA70; Zap70; ZAP-70; Zeta chain associated protein kinase 70kDa; zeta chain of T cell receptor associated protein kinase; zeta chain of T cell receptor associated protein kinase 70; zeta chain of T cell receptor associated protein kinase 70kDa; zeta-chain (TCR) associated protein kinase; zeta-chain (TCR) associated protein kinase 70; zeta-chain (TCR) associated protein kinase 70kDa; zeta-chain associated protein kinase 70kDa; zeta-chain associated protein kinase, 70kD

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100147296, 100271860, 100739325, 100767740, 22637, 301348, 420086, 504509, 7535

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Clone

R.658.6

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P43403, P43404

Gene Symbols

LOC100739325, LOC100767740, ZAP70

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pTyr319 of human Zap-70

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Bovine, Canine, Chicken, Equine, Hamster, Human, Mouse, Non-human Primate, Porcine, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIMA512624

--

Img

Thermo Scientific

PIMA515553

--

Img

Thermo Scientific

PIMA514925

--

Img

Thermo Scientific

PIMA515175

--

Img

Thermo Scientific

PIMA514961

--

Img

Thermo Scientific

PIMA515228

--

Img

Thermo Scientific

PIMA514943

--

Img

Thermo Scientific

PIMA515040

--

Description

  • It is not recommended to aliquot this antibody
  • ZAP-70 is a cytosolic protein tyrosine kinase that is a member of the Syk family of proteins
  • ZAP-70 is expressed exclusively in T-cells and natural killer cells and is required for T-cell receptor activation
  • Upon T cell antigen receptor (TCR) engagement, ZAP70 is phosphorylated on tyrosines 292, 315 and 319 in the interdomain B, located between the SH2 and kinase domains
  • Phosphorylation of both tyrosines 315 (a Vav binding site) and 319 (a Lck binding site) enhances ZAP70 function in mediating lymphocyte signaling, while tyrosine 292 terminates the transient activation of ZAP70 and attentuates lymphocyte signaling.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA515095

--


Antigen:
Phospho-ZAP70/Syk (Tyr319, Tyr352)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ZAP70

Gene Alias:
70 kDa zeta-associated protein; 70 kDa zeta-chain associated protein; ADMIO2; EC 2.7.10.2; FLJ17670; FLJ17679; I79_004087; IMD48; kinase ZAP70; mrtle; mur; Selective T cell defect; Srk; STCD; STD; syk-related protein tyrosine kinase; syk-related tyrosine kinase; Tyrosine-protein kinase ZAP-70; Tyrosine-protein kinase ZAP-70;TZK; TZK; ZA70; Zap70; ZAP-70; Zeta chain associated protein kinase 70kDa; zeta chain of T cell receptor associated protein kinase; zeta chain of T cell receptor associated protein kinase 70; zeta chain of T cell receptor associated protein kinase 70kDa; zeta-chain (TCR) associated protein kinase; zeta-chain (TCR) associated protein kinase 70; zeta-chain (TCR) associated protein kinase 70kDa; zeta-chain associated protein kinase 70kDa; zeta-chain associated protein kinase, 70kD

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100147296, 100271860, 100739325, 100767740, 22637, 301348, 420086, 504509, 7535

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Clone:
R.658.6

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P43403, P43404

Gene Symbols:
LOC100739325, LOC100767740, ZAP70

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr319 of human Zap-70

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Chicken, Equine, Hamster, Human, Mouse, Non-human Primate, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIMA515098

--


Antigen:
Phospho-c-Abl (Tyr245)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ABL1

Gene Alias:
Abelson murine leukemia oncogene; Abelson murine leukemia viral (v-abl) oncogene homolog 1; abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Abl; Abl 1 antib; ABL proto-oncogene 1, non-receptor tyrosine kinase; Abl1; ABL2; ABLL; AI325092; ARG; B30; bcr/abl; bcr/c-abl oncogene protein; c-ABL; c-abl oncogene 1, non-receptor tyrosine kinase; c-abl oncogene 1, receptor tyrosine kinase; c-ABL1; E430008G22Rik; JTK7; p150; Proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; RP11-83J21.1; Tyrosine kinase ARG; tyrosine-protein kinase ABL1; v-abl; v-abl Abelson murine leukemia oncogene 1; v-abl Abelson murine leukemia viral oncogene 1; v-abl Abelson murine leukemia viral oncogene homolog 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11350, 25

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Clone:
S.44.4

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P00519, P00520

Gene Symbols:
ABL1

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr245 of human c-Abl

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIMA515101

--


Antigen:
EZH2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
EZH2

Gene Alias:
an; enhancer of zeste 2 polycomb repressive complex 2 subunit; enhancer of zeste homolog 2; enhancer of zeste homolog 2 (Drosophila); ENX 1; ENX1; Enx-1; Enx1h; EZH 2; EZH1; EZH2; EZH-2; EZH2b; histone-lysine N-methyltransferase EZH2; KMT6; KMT6A; lysine N-methyltransferase 6; mKIAA4065; OTTHUMP00000213774; OTTHUMP00000213778; OTTHUMP00000213779; OTTHUMP00000213780; WVS; WVS2

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14056, 2146, 312299

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Clone:
H.547.3

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
Q15910, Q61188

Gene Symbols:
EZH2

Immunogen:
Ezh2 recombinant protein containing human Ezh2 residues 351-453

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515102

--


Antigen:
Phospho-ErbB4 (Tyr1284)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ERBB4

Gene Alias:
4ICD; ALS19; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; avian erythroblastosis oncogene B 4; c-erbB-4; erb-b2 receptor tyrosine kinase 4; Erbb4; ERBB4 intracellular domain; ERBB4 transcript variant I12DEL; ERBB4 transcript variant I20DEL; Her4; human epidermal growth factor receptor 4; Mer4; OTTHUMP00000209432; p180erbB4; proto-oncogene-like protein c-ErbB-4; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-4; s80HER4; Tyro-2; Tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v-erb-b2 avian erythroblastic leukemia viral oncogene 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2066

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Clone:
R.912.5

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
Q15303

Gene Symbols:
ERBB4

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr1284 of human HER4/ErbB4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG