PIMA515102

Phospho-ErbB4 (Tyr1284) Monoclonal Antibody (R.912.5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515102-Each-of-1 In Stock ₹ 45,646.26

PIMA515102 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

Phospho-ErbB4 (Tyr1284)

Classification

Monoclonal

Concentration

139 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

Q15303

Gene Symbols

ERBB4

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pTyr1284 of human HER4/ErbB4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

R.912.5

Conjugate

Unconjugated

Gene

ERBB4

Gene Alias

4ICD; ALS19; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; avian erythroblastosis oncogene B 4; c-erbB-4; erb-b2 receptor tyrosine kinase 4; Erbb4; ERBB4 intracellular domain; ERBB4 transcript variant I12DEL; ERBB4 transcript variant I20DEL; Her4; human epidermal growth factor receptor 4; Mer4; OTTHUMP00000209432; p180erbB4; proto-oncogene-like protein c-ErbB-4; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-4; s80HER4; Tyro-2; Tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v-erb-b2 avian erythroblastic leukemia viral oncogene 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2066

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • This antibody is not cross-reactive with other ErbB family members
  • Oncogene ERBB4 (HER4) is a member of the type I receptor protein tyrosine subfamily that includes EGFR, ERBB2, and ERBB3
  • ERBB4 binds and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation
  • ErbB 4 is activated by neuregulins and NTAK (neural and thymus derived activator for ErbB kinases)
  • ErbB 4 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself
  • Like other protein kinases, ErbB 4 mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation
  • ErbB 4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum
  • Breast tumor cell lines T47-D, MDA-MB-453, BT-474 and H3396 are found to have the highest levels of mRNA, and intermediate levels are seen in MCF-7, MDAMB-330 and MDA-MB-361
  • Expression of ErbB 4 is low or absent in some breast tumor cell lines such as MDA-MB-231, MDA-MB-157, MDA-MB-468, and SKBR-3
  • ErbB 4 levels have been found to be elevated in certain human tumor cell lines suggesting that it may play a role in some malignancies.

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Thermo Scientific

PIMA515102

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Antigen:
Phospho-ErbB4 (Tyr1284)

Classification:
Monoclonal

Concentration:
139 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
Q15303

Gene Symbols:
ERBB4

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr1284 of human HER4/ErbB4

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
R.912.5

Conjugate:
Unconjugated

Gene:
ERBB4

Gene Alias:
4ICD; ALS19; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; avian erythroblastosis oncogene B 4; c-erbB-4; erb-b2 receptor tyrosine kinase 4; Erbb4; ERBB4 intracellular domain; ERBB4 transcript variant I12DEL; ERBB4 transcript variant I20DEL; Her4; human epidermal growth factor receptor 4; Mer4; OTTHUMP00000209432; p180erbB4; proto-oncogene-like protein c-ErbB-4; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-4; s80HER4; Tyro-2; Tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v-erb-b2 avian erythroblastic leukemia viral oncogene 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2066

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515107

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Antigen:
CD56

Classification:
Monoclonal

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P13591

Gene Symbols:
Ncam1

Immunogen:
Membrane preparation of a small cell lung carcinoma specimen

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
G.611.8

Conjugate:
Unconjugated

Gene:
Ncam1

Gene Alias:
adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4684

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515108

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Antigen:
Tau

Classification:
Monoclonal

Concentration:
646 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P10636, P10637, P19332

Gene Symbols:
MAPT

Immunogen:
Native bovine tau and the epitope maps to the carboxy-terminus of the protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
S.125.0

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17762, 29477, 4137

Content And Storage:
-20°C

Form:
Liquid

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Thermo Scientific

PIMA515111

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Antigen:
AMPK alpha-1

Classification:
Monoclonal

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P54645, Q13131, Q5EG47

Gene Symbols:
Prkaa1

Immunogen:
Synthetic peptide corresponding to the amino-terminal sequence of human AMPKa

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
C.458.5

Conjugate:
Unconjugated

Gene:
Prkaa1

Gene Alias:
5'-AMP-activated protein kinase alpha-1 catalytic subunit; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; 63 kDa subunit; AAPK2; ACACA kinase; Acetyl-CoA carboxylase kinase; activated protein kinase; AI194361; AI450832; AL024255; AMP -activate kinase alpha 1 subunit; AMP activated protein kinase; AMP-activated protein kinase, alpha 1 catalytic subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK; AMPK 63 kDa subunit; AMPK alpha 1; AMPK alpha-1 chain; AMPK subunit alpha-1; AMPK subunit pAMPK; AMPK1; AMPK2; AMPKa1; AMPKalpha1; AMPK-alpha-2 chain; C130083N04Rik; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; MGC33776; MGC57364; pAMPK; PRKAA; Prkaa1; PRKAA2; protein kinase; protein kinase AMP-activated catalytic subunit alpha 1; protein kinase, AMP-activated, alpha 1 catalytic subunit; tau-protein kinase PRKAA1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
105787, 5562, 65248

Content And Storage:
-20°C

Form:
Liquid