PIMA516349
ErbB3 Monoclonal Antibody (SP71), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516349-Each-of-1 | In Stock | ₹ 57,239.64 |
PIMA516349 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 57,239.64
GST (18%): ₹ 10,303.135
Total Price: ₹ 67,542.775
Antigen
ErbB3
Classification
Monoclonal
Concentration
0.048 mg/mL
Formulation
PBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene Accession No.
P21860
Gene Symbols
ERBB3
Immunogen
Synthetic peptide corresponding to internal region of human c-erbB3
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunohistochemistry (Paraffin)
Clone
SP71
Conjugate
Unconjugated
Gene
ERBB3
Gene Alias
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Host Species
Rabbit
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
2065
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min
- Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature
- A suggested positive control is small intestine tissue
- ErbB3 (c-erbB-3/HER-3) is a member of the type I family of growth factor receptors and binds to ligands in the heregulin family
- ErbB3 is over-expressed in a variety of tumors in the prostate, bladder, breast, stomach, pancreas, and colon
- Heregulin and EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents
- The ErbB3 gene is located on the long arm of human chromosome 12 (12q13) and is transcribed into a 6
- 2kb mRNA which is translated into a 160/180 kDa glycoprotein
- The ErbB3 gene encodes a transmembrane receptor tyrosine kinase due to alternative splicing and forms heterodimers with other EGF receptor family members that have kinase activity
- Heterodimerization leads to the activation of pathways that lead to cell proliferation or differentiation
- Alternate transcriptional splice variants encoding different isoforms of ErbB3 have been characterized
- One ErbB3 isoform lacks the intermembrane region, is secreted outside the cell, and acts to modulate the activity of the membrane-bound form
- Additional splice variants have also been reported, but they have not been thoroughly characterized.
Compare Similar Items
Show Difference
Antigen: ErbB3
Classification: Monoclonal
Concentration: 0.048 mg/mL
Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene Accession No.: P21860
Gene Symbols: ERBB3
Immunogen: Synthetic peptide corresponding to internal region of human c-erbB3
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
Clone: SP71
Conjugate: Unconjugated
Gene: ERBB3
Gene Alias: avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 2065
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ErbB3
Classification:
Monoclonal
Concentration:
0.048 mg/mL
Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene Accession No.:
P21860
Gene Symbols:
ERBB3
Immunogen:
Synthetic peptide corresponding to internal region of human c-erbB3
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin)
Clone:
SP71
Conjugate:
Unconjugated
Gene:
ERBB3
Gene Alias:
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
2065
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Tensin 4
Classification: Monoclonal
Concentration: 0.05 mg/mL
Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene Accession No.: Q8IZW8
Gene Symbols: TNS4
Immunogen: Synthetic peptide corresponding to C-terminus of human CTEN protein
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
Clone: SP83
Conjugate: Unconjugated
Gene: TNS4
Gene Alias: 9930017A07Rik; AA589547; AU016405; C terminal tensin like; CTEN; c-ten; C-terminal tensin-like protein; PP14434; RGD1310402; tensin 4; tensin-4; TNS4
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 84951
Content And Storage: 4° C
Form: Liquid
Antigen:
Tensin 4
Classification:
Monoclonal
Concentration:
0.05 mg/mL
Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene Accession No.:
Q8IZW8
Gene Symbols:
TNS4
Immunogen:
Synthetic peptide corresponding to C-terminus of human CTEN protein
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin)
Clone:
SP83
Conjugate:
Unconjugated
Gene:
TNS4
Gene Alias:
9930017A07Rik; AA589547; AU016405; C terminal tensin like; CTEN; c-ten; C-terminal tensin-like protein; PP14434; RGD1310402; tensin 4; tensin-4; TNS4
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
84951
Content And Storage:
4° C
Form:
Liquid
Antigen: Cyclin D1
Classification: Recombinant Monoclonal
Concentration: 0.045 mg/mL
Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.: P24385, P25322, P39948
Gene Symbols: CCND1
Immunogen: Synthetic peptide from C-terminus of human cyclin D1.
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: SP4
Conjugate: Unconjugated
Gene: CCND1
Gene Alias: AI327039; B-cell CLL/lymphoma 1; B-cell lymphoma 1 protein; BCL1; BCL-1; BCL-1 oncogene; CCND1; CCND1 protein; cD1; cDNA; CycD1; cyclin D1; Cyl-1; D11S287E; FLJ93625; G1/S-specific cyclin-D1; mRNA; PRAD1; PRAD-1; PRAD1 oncogene; U21B31
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 12443, 58919, 595
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Cyclin D1
Classification:
Recombinant Monoclonal
Concentration:
0.045 mg/mL
Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.:
P24385, P25322, P39948
Gene Symbols:
CCND1
Immunogen:
Synthetic peptide from C-terminus of human cyclin D1.
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
SP4
Conjugate:
Unconjugated
Gene:
CCND1
Gene Alias:
AI327039; B-cell CLL/lymphoma 1; B-cell lymphoma 1 protein; BCL1; BCL-1; BCL-1 oncogene; CCND1; CCND1 protein; cD1; cDNA; CycD1; cyclin D1; Cyl-1; D11S287E; FLJ93625; G1/S-specific cyclin-D1; mRNA; PRAD1; PRAD-1; PRAD1 oncogene; U21B31
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
12443, 58919, 595
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: DOG-1
Classification: Recombinant Monoclonal
Concentration: 0.057 mg/mL
Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.: Q5XXA6
Gene Symbols: ANO1
Immunogen: Synthetic peptides of human DOG-1 protein
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: SP31
Conjugate: Unconjugated
Gene: ANO1
Gene Alias: ANO1; anoctamin 1; anoctamin 1, calcium activated chloride channel; anoctamin-1; Ca2+-activated Cl- channel; calcium activated chloride channel; discovered on gastrointestinal stromal tumors protein 1; DOG1; FLJ10261; oral cancer overexpressed 2; Oral cancer overexpressed protein 2; ORAOV2; TAOS2; Tmem16a; Transmembrane protein 16A; transmembrane protein 16A (eight membrane-spanning domains); tumor-amplified and overexpressed sequence 2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 55107
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
DOG-1
Classification:
Recombinant Monoclonal
Concentration:
0.057 mg/mL
Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.:
Q5XXA6
Gene Symbols:
ANO1
Immunogen:
Synthetic peptides of human DOG-1 protein
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
SP31
Conjugate:
Unconjugated
Gene:
ANO1
Gene Alias:
ANO1; anoctamin 1; anoctamin 1, calcium activated chloride channel; anoctamin-1; Ca2+-activated Cl- channel; calcium activated chloride channel; discovered on gastrointestinal stromal tumors protein 1; DOG1; FLJ10261; oral cancer overexpressed 2; Oral cancer overexpressed protein 2; ORAOV2; TAOS2; Tmem16a; Transmembrane protein 16A; transmembrane protein 16A (eight membrane-spanning domains); tumor-amplified and overexpressed sequence 2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
55107
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid