PIMA515039

Phospho-ErbB3 (Tyr1222) Monoclonal Antibody (K.95.1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515039-Each-of-1 In Stock ₹ 45,646.26

PIMA515039 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

Phospho-ErbB3 (Tyr1222)

Classification

Monoclonal

Conjugate

Unconjugated

Gene

ERBB3

Gene Alias

avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2065

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Clone

K.95.1

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P21860

Gene Symbols

ERBB3

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pTyr1222 of human HER3/ErbB3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • It is not recommended to aliquot this antibody
  • This antibody is not cross-reactive with other tyrosine phosphorylated receptor tyrosine kinases
  • ErbB3 (c-erbB-3/HER-3) is a member of the type I family of growth factor receptors and binds to ligands in the heregulin family
  • ErbB3 is over-expressed in a variety of tumors in the prostate, bladder, breast, stomach, pancreas, and colon
  • Heregulin and EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents
  • The ErbB3 gene is located on the long arm of human chromosome 12 (12q13) and is transcribed into a 6
  • 2kb mRNA which is translated into a 160/180 kDa glycoprotein
  • The ErbB3 gene encodes a transmembrane receptor tyrosine kinase due to alternative splicing and forms heterodimers with other EGF receptor family members that have kinase activity
  • Heterodimerization leads to the activation of pathways that lead to cell proliferation or differentiation
  • Alternate transcriptional splice variants encoding different isoforms of ErbB3 have been characterized
  • One ErbB3 isoform lacks the intermembrane region, is secreted outside the cell, and acts to modulate the activity of the membrane-bound form
  • Additional splice variants have also been reported, but they have not been thoroughly characterized.

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Img

Thermo Scientific

PIMA515039

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Antigen:
Phospho-ErbB3 (Tyr1222)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
ERBB3

Gene Alias:
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2065

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Clone:
K.95.1

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P21860

Gene Symbols:
ERBB3

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr1222 of human HER3/ErbB3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIMA515040

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Antigen:
RSK1/RSK2/RSK3

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
Rps6ka1

Gene Alias:
90 kDa ribosomal protein S6 kinase 1; 90 kDa ribosomal protein S6 kinase 2; 90 kDa ribosomal protein S6 kinase 3; 90kDa; C130006E23; CLS; D17Wsu134e; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); HU-1; HU-2; HU-3; Insulin-stimulated protein kinase 1; ISPK1; ISPK-1; MAP kinase-activated protein kinase 1; MAP kinase-activated protein kinase 1a; MAP kinase-activated protein kinase 1b; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1; MAPK-activated protein kinase 1a; MAPK-activated protein kinase 1b; MAPK-activated protein kinase 1c; MAPKAP kinase 1; MAPKAP kinase 1a; MAPKAP kinase 1b; MAPKAP kinase 1C; MAPKAPK-1; MAPKAPK1A; MAPKAPK-1a; MAPKAPK1B; MAPKAPK-1b; Mapkapk1c; MAPKAPK-1c; mitogen-activated protein kinase-activated protein kinase 1C; MPK-9; MRX19; p90 rsk; p90Rsk; p90-RSK; p90-RSK 1; p90-RSK 2; p90-RSK 3; p90Rsk1; p90-Rsk1; p90RSK2; p90-RSK2; p90RSK3; p90-RSK3; p90S6K; pp90rsk; pp90RSK1; pp90RSK2; pp90RSK3; protein-tyrosine kinase Mpk-9; RG

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100721226, 100728619, 100729439, 110651, 117269, 20111, 20112, 501560, 6195, 6196, 6197, 81771

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
F.940.7

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P18653, P18654, P51812, Q15349, Q15418, Q63531, Q9WUT3

Gene Symbols:
Rps6ka1, RPS6KA2, RPS6KA3

Immunogen:
Synthetic peptide corresponding to residues surrounding Asp659 of human p90RSK

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Guinea Pig, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIMA515044

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Antigen:
NQO1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
NQO1

Gene Alias:
AV001255; Azoreductase; DHQU; DIA4; Diaphorase (NADH/NADPH); diaphorase (NADH/NADPH) (cytochrome b-5 reductase); Diaphorase 4; diaphorase 4 (NADH/NADPH); diaphorase-4; dioxin-inducible 1; DTD; DT-diaphorase; menadione reductase; NAD(P)H dehydrogenase (quinone); NAD(P)H dehydrogenase [quinone] 1; NAD(P)H dehydrogenase, quinone 1; NAD(P)H menadione oxidoreductase 1, dioxin inducible; NAD(P)H quinone dehydrogenase 1; NAD(P)H: quinone oxidoreductase 1; NAD(P)H:menadione oxidoreductase; NAD(P)H:menadione oxidoreductase 1; NAD(P)H:Quinone acceptor oxidoreductase type 1; NAD(P)H:quinone oxidoreductase 1; NAD(P)H:quinone oxireductase; NADPH-d; nicotinamide adenine dinucleotide phosphate diaphorase; Nmo1; Nmo-1; Nmor1; NMORI; NQ01; NQO1; Ox1; Ox-1; phylloquinone reductase; QR1; quinone reductase 1

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1728

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
F.964.4

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P15559

Gene Symbols:
NQO1

Immunogen:
Purified recombinant human NQO1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515046

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Antigen:
Phospho-Bcl-2 (Ser70)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
Bcl2

Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
R.65.1

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P10415

Gene Symbols:
Bcl2

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding serine 70 of human Bcl-2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG