PIMA515108
Tau Monoclonal Antibody (S.125.0), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515108-Each-of-1 | In Stock | ₹ 51,250.44 |
PIMA515108 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,250.44
GST (18%): ₹ 9,225.079
Total Price: ₹ 60,475.519
Antigen
Tau
Classification
Monoclonal
Concentration
646 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
P10636, P10637, P19332
Gene Symbols
MAPT
Immunogen
Native bovine tau and the epitope maps to the carboxy-terminus of the protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
S.125.0
Conjugate
Unconjugated
Gene
MAPT
Gene Alias
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17762, 29477, 4137
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- Tau is a neuronal microtubule-associated protein found predominantly on axons
- The function of Tau is to promote tubulin polymerization and stabilize microtubules
- The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
- Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
- The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
- In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain
- Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, μgtimately leading to the degeneration of the affected neurons
- Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
- Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
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Antigen: Tau
Classification: Monoclonal
Concentration: 646 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P10636, P10637, P19332
Gene Symbols: MAPT
Immunogen: Native bovine tau and the epitope maps to the carboxy-terminus of the protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: S.125.0
Conjugate: Unconjugated
Gene: MAPT
Gene Alias: AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17762, 29477, 4137
Content And Storage: -20°C
Form: Liquid
Antigen:
Tau
Classification:
Monoclonal
Concentration:
646 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P10636, P10637, P19332
Gene Symbols:
MAPT
Immunogen:
Native bovine tau and the epitope maps to the carboxy-terminus of the protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
S.125.0
Conjugate:
Unconjugated
Gene:
MAPT
Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17762, 29477, 4137
Content And Storage:
-20°C
Form:
Liquid
Antigen: AMPK alpha-1
Classification: Monoclonal
Concentration: __
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P54645, Q13131, Q5EG47
Gene Symbols: Prkaa1
Immunogen: Synthetic peptide corresponding to the amino-terminal sequence of human AMPKa
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: C.458.5
Conjugate: Unconjugated
Gene: Prkaa1
Gene Alias: 5'-AMP-activated protein kinase alpha-1 catalytic subunit; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; 63 kDa subunit; AAPK2; ACACA kinase; Acetyl-CoA carboxylase kinase; activated protein kinase; AI194361; AI450832; AL024255; AMP -activate kinase alpha 1 subunit; AMP activated protein kinase; AMP-activated protein kinase, alpha 1 catalytic subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK; AMPK 63 kDa subunit; AMPK alpha 1; AMPK alpha-1 chain; AMPK subunit alpha-1; AMPK subunit pAMPK; AMPK1; AMPK2; AMPKa1; AMPKalpha1; AMPK-alpha-2 chain; C130083N04Rik; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; MGC33776; MGC57364; pAMPK; PRKAA; Prkaa1; PRKAA2; protein kinase; protein kinase AMP-activated catalytic subunit alpha 1; protein kinase, AMP-activated, alpha 1 catalytic subunit; tau-protein kinase PRKAA1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 105787, 5562, 65248
Content And Storage: -20°C
Form: Liquid
Antigen:
AMPK alpha-1
Classification:
Monoclonal
Concentration:
__
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P54645, Q13131, Q5EG47
Gene Symbols:
Prkaa1
Immunogen:
Synthetic peptide corresponding to the amino-terminal sequence of human AMPKa
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
C.458.5
Conjugate:
Unconjugated
Gene:
Prkaa1
Gene Alias:
5'-AMP-activated protein kinase alpha-1 catalytic subunit; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; 63 kDa subunit; AAPK2; ACACA kinase; Acetyl-CoA carboxylase kinase; activated protein kinase; AI194361; AI450832; AL024255; AMP -activate kinase alpha 1 subunit; AMP activated protein kinase; AMP-activated protein kinase, alpha 1 catalytic subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK; AMPK 63 kDa subunit; AMPK alpha 1; AMPK alpha-1 chain; AMPK subunit alpha-1; AMPK subunit pAMPK; AMPK1; AMPK2; AMPKa1; AMPKalpha1; AMPK-alpha-2 chain; C130083N04Rik; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; MGC33776; MGC57364; pAMPK; PRKAA; Prkaa1; PRKAA2; protein kinase; protein kinase AMP-activated catalytic subunit alpha 1; protein kinase, AMP-activated, alpha 1 catalytic subunit; tau-protein kinase PRKAA1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
105787, 5562, 65248
Content And Storage:
-20°C
Form:
Liquid
Antigen: PLK1
Classification: Monoclonal
Concentration: 38 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P53350, Q62673
Gene Symbols: Plk1
Immunogen: Synthetic peptide corresponding to residues near the carboxy terminus of human PLK1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: E.456.6
Conjugate: Unconjugated
Gene: Plk1
Gene Alias: cell cycle regulated protein kinase; Plk; PLK 1; Plk1; PLK-1; plk1.S; plx1; polo (Drosophia)-like kinase; polo like kinase; polo like kinase 1; polo like kinase 1 S homeolog; polo-like kinase; polo-like kinase 1; polo-like kinase homolog; polo-like protein kinase; serine/threonine-protein kinase 13; Serine/threonine-protein kinase PLK1; STPK13; STPK14; Unknown (protein for MGC:133927); XELAEV_18047692mg
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 25515, 5347
Content And Storage: -20°C
Form: Liquid
Antigen:
PLK1
Classification:
Monoclonal
Concentration:
38 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P53350, Q62673
Gene Symbols:
Plk1
Immunogen:
Synthetic peptide corresponding to residues near the carboxy terminus of human PLK1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
E.456.6
Conjugate:
Unconjugated
Gene:
Plk1
Gene Alias:
cell cycle regulated protein kinase; Plk; PLK 1; Plk1; PLK-1; plk1.S; plx1; polo (Drosophia)-like kinase; polo like kinase; polo like kinase 1; polo like kinase 1 S homeolog; polo-like kinase; polo-like kinase 1; polo-like kinase homolog; polo-like protein kinase; serine/threonine-protein kinase 13; Serine/threonine-protein kinase PLK1; STPK13; STPK14; Unknown (protein for MGC:133927); XELAEV_18047692mg
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
25515, 5347
Content And Storage:
-20°C
Form:
Liquid
Antigen: Phospho-c-Jun (Ser63)
Classification: Monoclonal
Concentration: 1 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P05412, P05627, P17325
Gene Symbols: JUN
Immunogen: Synthetic phosphopeptide corresponding to residues around pSer63 of human c-Jun
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: J.973.7
Conjugate: Unconjugated
Gene: JUN
Gene Alias: Activator protein 1; AH119; AP1; AP-1; Avian sarcoma virus 17 (v-jun) oncogene homolog; cjun; c-Jun; c-jun transcription factor; enhancer-binding protein AP1; I79_009953; immediate early; JUN; Jun A; Jun activation domain binding protein; Jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; Junc; JUND; p39; proto-oncogene c-Jun; Rjg-9; transcription factor; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16476, 24516, 3725
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-c-Jun (Ser63)
Classification:
Monoclonal
Concentration:
1 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P05412, P05627, P17325
Gene Symbols:
JUN
Immunogen:
Synthetic phosphopeptide corresponding to residues around pSer63 of human c-Jun
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
J.973.7
Conjugate:
Unconjugated
Gene:
JUN
Gene Alias:
Activator protein 1; AH119; AP1; AP-1; Avian sarcoma virus 17 (v-jun) oncogene homolog; cjun; c-Jun; c-jun transcription factor; enhancer-binding protein AP1; I79_009953; immediate early; JUN; Jun A; Jun activation domain binding protein; Jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; Junc; JUND; p39; proto-oncogene c-Jun; Rjg-9; transcription factor; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16476, 24516, 3725
Content And Storage:
-20°C
Form:
Liquid