PIMA515004
TSC2 Monoclonal Antibody (T.309.0), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515004-Each-of-1 | In Stock | ₹ 43,165.02 |
PIMA515004 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,165.02
GST (18%): ₹ 7,769.704
Total Price: ₹ 50,934.724
Antigen
TSC2
Classification
Monoclonal
Concentration
270 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
P49815
Gene Symbols
TSC2
Immunogen
Synthetic peptide from the amino terminus of human tuberin.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunoprecipitation, Western Blot
Clone
T.309.0
Conjugate
Unconjugated
Gene
TSC2
Gene Alias
LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7249
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- TSC2 (Tuberin, Tuberous sclerosis complex, TSC Complex Subunit 2), is implicated as a tumor suppressor and may function in vesicular transport, play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
- TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin
- Phosphorylation of tuberin on Ser 939 and Thr 1462 regulates its interaction with hamartin, and is stimulated by various growth factors through the phosphoinositide 3-kinase/Akt pathway
- TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
- Interaction between TSC1 and TSC2 may facilitate vesicular docking
- TSC2 specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth
- Mutations in TSC2 lead to constitutive activation of RAP1A in tumors and are involved in diseases such as lymphangioleiomyomatosis and TSC2 angiomyolipoma
- Alternative splicing results in transcript variants of three different isoforms of TSC2.
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Antigen: TSC2
Classification: Monoclonal
Concentration: 270 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P49815
Gene Symbols: TSC2
Immunogen: Synthetic peptide from the amino terminus of human tuberin.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Clone: T.309.0
Conjugate: Unconjugated
Gene: TSC2
Gene Alias: LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7249
Content And Storage: -20°C
Form: Liquid
Antigen:
TSC2
Classification:
Monoclonal
Concentration:
270 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P49815
Gene Symbols:
TSC2
Immunogen:
Synthetic peptide from the amino terminus of human tuberin.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Clone:
T.309.0
Conjugate:
Unconjugated
Gene:
TSC2
Gene Alias:
LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7249
Content And Storage:
-20°C
Form:
Liquid
Antigen: 4EBP1
Classification: Monoclonal
Concentration: 169 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: Q13541, Q60876, Q62622
Gene Symbols: EIF4EBP1
Immunogen: Synthetic peptide corresponding to residues surrounding Ser112 of human 4E-BP1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: E.992.6
Conjugate: Unconjugated
Gene: EIF4EBP1
Gene Alias: 4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116636, 13685, 1978
Content And Storage: -20°C
Form: Liquid
Antigen:
4EBP1
Classification:
Monoclonal
Concentration:
169 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
Q13541, Q60876, Q62622
Gene Symbols:
EIF4EBP1
Immunogen:
Synthetic peptide corresponding to residues surrounding Ser112 of human 4E-BP1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
E.992.6
Conjugate:
Unconjugated
Gene:
EIF4EBP1
Gene Alias:
4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116636, 13685, 1978
Content And Storage:
-20°C
Form:
Liquid
Antigen: RICTOR
Classification: Monoclonal
Concentration: 172 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: Q6QI06, Q6R327
Gene Symbols: Rictor
Immunogen: Synthetic peptide corresponding to the sequence Gln1681 of human Rictor
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: J.644.6
Conjugate: Unconjugated
Gene: Rictor
Gene Alias: 4921505C17Rik; 6030405M08Rik; AVO3; AVO3 homolog; AW492497; D530039E11Rik; DKFZp686B11164; Fyb; FYN binding protein; hAVO3; Kiaa1999; mAVO3; MGC39830; PIA; pianissimo; protein pianissimo; Rapamycin-insensitive companion of mTOR; rictor; RPTOR independent companion of MTOR complex 2; RPTOR independent companion of MTOR, complex 2; TORC2-specific protein AVO3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 253260, 310131, 78757
Content And Storage: -20°C
Form: Liquid
Antigen:
RICTOR
Classification:
Monoclonal
Concentration:
172 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
Q6QI06, Q6R327
Gene Symbols:
Rictor
Immunogen:
Synthetic peptide corresponding to the sequence Gln1681 of human Rictor
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
J.644.6
Conjugate:
Unconjugated
Gene:
Rictor
Gene Alias:
4921505C17Rik; 6030405M08Rik; AVO3; AVO3 homolog; AW492497; D530039E11Rik; DKFZp686B11164; Fyb; FYN binding protein; hAVO3; Kiaa1999; mAVO3; MGC39830; PIA; pianissimo; protein pianissimo; Rapamycin-insensitive companion of mTOR; rictor; RPTOR independent companion of MTOR complex 2; RPTOR independent companion of MTOR, complex 2; TORC2-specific protein AVO3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
253260, 310131, 78757
Content And Storage:
-20°C
Form:
Liquid
Antigen: PPP2R2A
Classification: Monoclonal
Concentration: 104 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P36876, P63151, Q6P1F6
Gene Symbols: PPP2R2A
Immunogen: Synthetic peptide corresponding to the sequence of human PP2A B subunit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Drosophila, Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: F.722.1
Conjugate: Unconjugated
Gene: PPP2R2A
Gene Alias: 2410004D02Rik; B55A; B55ALPHA; hypothetical protein; mKIAA1541; PP2A subunit B isoform alpha; PP2A subunit B isoform B55-alpha; PP2A subunit B isoform BRA; PP2A subunit B isoform PR55-alpha; PP2A subunit B isoform R2-alpha; PP2A, subunit B, B55-alpha isoform; PP2A, subunit B, B-alpha isoform; PP2A, subunit B, BRA isoform; PP2A, subunit B, PR55-alpha isoform; PP2A, subunit B, R2-alpha isoform; PPP2R2A; PR52A; PR55A; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR52), alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform; protein phosphatase 2 regulatory subunit B, alpha; protein phosphatase 2 regulatory subunit Balpha; protein phosphatase 2, regulatory subunit B, alpha; protein phosphatase 2A 55 kDa regulatory subunit, alpha isoform; serine/threonine protein phosphatase 2A, 55 KDA regulatory subunit B, alpha isoform; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; serine-threonine protein phosphatase 2A regulatory subunit; testicular tissue protein Li 156
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 117104, 5520, 71978
Content And Storage: -20°C
Form: Liquid
Antigen:
PPP2R2A
Classification:
Monoclonal
Concentration:
104 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P36876, P63151, Q6P1F6
Gene Symbols:
PPP2R2A
Immunogen:
Synthetic peptide corresponding to the sequence of human PP2A B subunit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Drosophila, Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
F.722.1
Conjugate:
Unconjugated
Gene:
PPP2R2A
Gene Alias:
2410004D02Rik; B55A; B55ALPHA; hypothetical protein; mKIAA1541; PP2A subunit B isoform alpha; PP2A subunit B isoform B55-alpha; PP2A subunit B isoform BRA; PP2A subunit B isoform PR55-alpha; PP2A subunit B isoform R2-alpha; PP2A, subunit B, B55-alpha isoform; PP2A, subunit B, B-alpha isoform; PP2A, subunit B, BRA isoform; PP2A, subunit B, PR55-alpha isoform; PP2A, subunit B, R2-alpha isoform; PPP2R2A; PR52A; PR55A; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR52), alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform; protein phosphatase 2 regulatory subunit B, alpha; protein phosphatase 2 regulatory subunit Balpha; protein phosphatase 2, regulatory subunit B, alpha; protein phosphatase 2A 55 kDa regulatory subunit, alpha isoform; serine/threonine protein phosphatase 2A, 55 KDA regulatory subunit B, alpha isoform; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; serine-threonine protein phosphatase 2A regulatory subunit; testicular tissue protein Li 156
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
117104, 5520, 71978
Content And Storage:
-20°C
Form:
Liquid