PIMA514855

Axl Monoclonal Antibody (C.995.0), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA514855-Each-of-1 In Stock ₹ 42,138.30

PIMA514855 - Each of 1

₹ 42,138.30

In Stock

Quantity

1

Base Price: ₹ 42,138.30

GST (18%): ₹ 7,584.894

Total Price: ₹ 49,723.194

Antigen

Axl

Classification

Monoclonal

Concentration

64 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P30530

Gene Symbols

AXL

Immunogen

Recombinant human fragment of the Axl protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

C.995.0

Conjugate

Unconjugated

Gene

AXL

Gene Alias

Adhesion-related kinase; AI323647; ARK; AXL; AXL oncogene; AXL receptor tyrosine kinase; AXL transforming sequence/gene; AZF1; JTK11; oncogene AXL; sAXL; soluble AXL; Tyro7; Tyrosine-protein kinase receptor UFO; Ufo; ufo oncogene homolog

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

558

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • This antibody is not cross-reactive with related proteins
  • AXL is a chronic myelogenous leukemia-associated oncogene that is also associated with colon cancer and melanoma
  • The AXL protein is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6, and is involved in the stimulation of cell proliferation
  • TAM receptors are also involved in phagocytosis of apoptotic cells
  • Mice lacking all three TAM receptors have several degenerative phenotypes linked to inefficient removal of apoptotic cells and membranes (e.g., in the retina and the male reproductive tract) and develop a severe autoimmune phenotype akin to systemic lupus erythematosus, including the production of broad spectrum auto-antibodies
  • In addition, Axl may function as a putative entry receptor for filoviruses
  • Axl is also used to identify a specific subpopulation of human blood dendritic cells, also referred to as Siglec 6+/Axl+ dendritic cells
  • Cellular expression of Axl can be upregulated by TLR ligands, such as LPS or poly I:C
  • Soluble Axl is generated by proteolytic cleavage of the membrane form
  • Increased plasma levels may be indicative of inflammation and cancer.

Compare Similar Items

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Img

Thermo Scientific

PIMA514855

--


Antigen:
Axl

Classification:
Monoclonal

Concentration:
64 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P30530

Gene Symbols:
AXL

Immunogen:
Recombinant human fragment of the Axl protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
C.995.0

Conjugate:
Unconjugated

Gene:
AXL

Gene Alias:
Adhesion-related kinase; AI323647; ARK; AXL; AXL oncogene; AXL receptor tyrosine kinase; AXL transforming sequence/gene; AZF1; JTK11; oncogene AXL; sAXL; soluble AXL; Tyro7; Tyrosine-protein kinase receptor UFO; Ufo; ufo oncogene homolog

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
558

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514856

--


Antigen:
AP2 alpha

Classification:
Monoclonal

Concentration:
94.8 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P05549, P34056, P58197

Gene Symbols:
TFAP2A

Immunogen:
Synthetic peptide corresponding to human AP-2a

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
R.387.0

Conjugate:
Unconjugated

Gene:
TFAP2A

Gene Alias:
activating enhancer-binding protein 2 alpha; activating enhancer-binding protein 2-alpha; Activator protein 2; activator protein 2 alpha variant 4; activator protein 2 alpha variant 6; activator protein 2 alpha variant 7; AP2; AP-2; Ap-2 (a); AP-2 transcription factor; AP2alpha; AP-2alpha; AP2-alpha; Ap2tf; BOFS; ERF-1; FLJ51761; OTTHUMP00000214240; OTTHUMP00000214243; Tcfap2a; TFAP2; TFAP2A; transcription factor AP2; transcription factor AP-2 alpha; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); transcription factor AP-2, alpha; transcription factor AP-2-alpha; transcription factor AP-2-alpha-like; transcription factor; AP-2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21418, 306862, 7020

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514857

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Antigen:
Phospho-IKK alpha/beta (Ser176, Ser177)

Classification:
Monoclonal

Concentration:
88 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
O14920, O15111, O88351, Q60680

Gene Symbols:
CHUK, Ikbkb

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer177 of IKKβ

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
J.10.3

Conjugate:
Unconjugated

Gene:
Ikbkb

Gene Alias:
AI132552; AI256658; AIM-1; CHUK; Chuk1; component of inhibitor of nuclear factor kappa B kinase complex; conserved helix-loop-helix ubiquitous kinase; EC 2.7.11.10; Fbx24; Fbxo24; I kappa B kinase 1; i kappa-B kinase alpha; IkappaB kinase; I-kappa-B kinase 1; I-kappa-B kinase 2; IkappaB kinase alpha; I-kappa-B kinase alpha; I-kappa-B kinase-alpha; I-kappa-B-kinase beta; IkB kinase alpha subunit; IkB kinase-alpha; IkB kinase-beta; ikBKA; Ikbkb; IKK alpha; IKK[b]; IKK1; IKK2; IKK-2; IKKA; IKK-A; IKK-a kinase; IKK-alpha; Ikkb; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa B kinase subunit beta; inhibitor of nuclear factor kappa-B kinase subunit alpha; Inhibitor of nuclear factor kappa-B kinase subunit beta; NFKBIKA; NFKBIKB; Nuclear factor NFkappaB inhibitor kinase alpha; nuclear factor NF-kappa-B inhibitor kinase alpha; Nuclear factor NF-kappa-B inhibitor kinase beta; TCF16; TCF-16; TCF17; Transcription factor 16

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1147, 12675, 16150, 3551

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514858

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Antigen:
Syntaxin 6

Classification:
Monoclonal

Concentration:
164 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
O43752, Q63635, Q9JKK1

Gene Symbols:
STX6

Immunogen:
Synthetic peptide corresponding to residues surrounding Tyr140 of mouse syntaxin 6 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
F.374.2

Conjugate:
Unconjugated

Gene:
STX6

Gene Alias:
2310039E05Rik; 2410005I16Rik; AA437559; AI415714; AI845861; HGNC:11441; STX6; Syn6; syntaxin 6; syntaxin-6

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10228, 58244, 60562

Content And Storage:
-20°C

Form:
Liquid