PIMA514843

FGFR3 Monoclonal Antibody (T.994.9), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA514843-Each-of-1 In Stock ₹ 45,132.90

PIMA514843 - Each of 1

₹ 45,132.90

In Stock

Quantity

1

Base Price: ₹ 45,132.90

GST (18%): ₹ 8,123.922

Total Price: ₹ 53,256.822

Antigen

FGFR3

Classification

Monoclonal

Concentration

27 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P22607

Gene Symbols

FGFR3

Immunogen

GST-FGFR-3 cytoplasmic domain fusion protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

T.994.9

Conjugate

Unconjugated

Gene

FGFR3

Gene Alias

ACH; CD333; CEK2; FGFR3; FGFR-3; FGFR3deltaTM; Fibroblast growth factor receptor 3; fibroblast growth factor receptor 3 variant 4; Flg-2; FR3; HBGFR; heparin-binding growth factor receptor; HSFGFR3EX; hydroxyaryl-protein kinase; JTK4; Mfr3; sam3; tyrosine kinase JTK4

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2261

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • This antibody is not cross-reactive with other related family members
  • FGFR3 is a member of the FGFR family of receptor tyrosine kinases
  • This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury
  • The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy
  • FGFR family members differ from one another in their ligand affinities and tissue distribution
  • A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain
  • The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, μgtimately influencing mitogenesis and differentiation
  • This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance
  • Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia
  • Three alternatively spliced transcript variants that encode different protein isoforms have been described.

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Img

Thermo Scientific

PIMA514843

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Antigen:
FGFR3

Classification:
Monoclonal

Concentration:
27 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P22607

Gene Symbols:
FGFR3

Immunogen:
GST-FGFR-3 cytoplasmic domain fusion protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
T.994.9

Conjugate:
Unconjugated

Gene:
FGFR3

Gene Alias:
ACH; CD333; CEK2; FGFR3; FGFR-3; FGFR3deltaTM; Fibroblast growth factor receptor 3; fibroblast growth factor receptor 3 variant 4; Flg-2; FR3; HBGFR; heparin-binding growth factor receptor; HSFGFR3EX; hydroxyaryl-protein kinase; JTK4; Mfr3; sam3; tyrosine kinase JTK4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2261

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514844

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Antigen:
SHIP2

Classification:
Monoclonal

Concentration:
14 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
O15357

Gene Symbols:
INPPL1

Immunogen:
Synthetic peptide corresponding to residues surrounding Ala1083 of human SHIP2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
T.194.8

Conjugate:
Unconjugated

Gene:
INPPL1

Gene Alias:
51C; 51C protein; ablSH3-binding protein; inositol polyphosphate phosphatase like 1; inositol polyphosphate phosphatase-like 1; inositol polyphosphate phosphatase-like protein 1; Inppl1; INPPL-1; OPSMD; Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2; protein 51C; SH2 domain-containing inositol 5'-phosphatase 2; SH2 domain-containing inositol phosphatase 2; SH2 domain-containing inositol-5'-phosphatase 2; SH2-containing inositol phosphatase 2; SHIP2; SHIP-2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3636

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514845

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Antigen:
OCT4

Classification:
Monoclonal

Concentration:
58 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P20263, Q01860

Gene Symbols:
POU5F1

Immunogen:
Recombinant protein specific to the amino terminus of human Oct-4A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
T.631.9

Conjugate:
Unconjugated

Gene:
POU5F1

Gene Alias:
2-Oct; 3-Oct; 4-Oct; cb197; chunp6868; DADB-104B20.2; etID49452.21; gp9; gp-9; HGNC:9221; homeobox protein; lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; MGC22487; NF-A3; Oct2; Oct-2; Oct2a; Oct2b; OCT3; Oct-3; Oct3/4; Oct-3/4; OCT4; Oct-4; Octamer-binding protein 2; octamer-binding protein 3; Octamer-binding protein 4; octamer-binding transcription factor 2; Octamer-binding transcription factor 3; OTF2; OTF-2; OTF3; Otf-3; Otf3g; Otf3-rs7; Otf4; Otf-4; OTTHUMP00000221150; OTTHUMP00000221151; POU class 2 homeobox 2; POU class 5 homeobox 1; POU class 5 homeobox 1 transcript variant OCT4B1; POU class 5 homeobox 1 transcript variant OCT4B2; POU class 5 homeobox 1 transcript variant OCT4B3; POU class 5 homeobox 1 transcript variant OCT4B4; POU class 5 homeobox 1 transcript variant OCT4B5; POU class 5 homeobox 1 transcript variant OCT4B6; POU domain class 5 transcription factor 1; POU domain gene 2; POU domain protein 2; POU domain transcription factor OCT4; POU domain, class 2, transcription factor 2; POU domain, class 5, transcription factor 1; POU domain, class 5, transcription factor 3; pou2; pou-2; POU2F2; Pou5f1; pou5f1 protein; pou5f3; POU-type homeodomain-containing DNA-binding protein; spg; spg/pou2; spiel-ohne-grenzen; spiel-ohne-grenzen/pou2; wu:fd18d06

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18999, 5460

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514846

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Antigen:
FOXO1

Classification:
Monoclonal

Concentration:
88 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
G3V7R4, Q12778, Q9R1E0

Gene Symbols:
FOXO1

Immunogen:
GST-fusion protein corresponding to carboxy-terminal residues of human FoxO1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
S.502.4

Conjugate:
Unconjugated

Gene:
FOXO1

Gene Alias:
Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2308, 56458, 84482

Content And Storage:
-20°C

Form:
Liquid