PIMA514918

Phospho-Syk (Tyr525, Tyr526) Monoclonal Antibody (F.724.5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA514918-Each-of-1 In Stock ₹ 46,245.18

PIMA514918 - Each of 1

₹ 46,245.18

In Stock

Quantity

1

Base Price: ₹ 46,245.18

GST (18%): ₹ 8,324.132

Total Price: ₹ 54,569.312

Antigen

Phospho-Syk (Tyr525, Tyr526)

Classification

Monoclonal

Concentration

90 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P43405

Gene Symbols

Syk

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pTyr525/526 of human Syk

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

F.724.5

Conjugate

Unconjugated

Gene

Syk

Gene Alias

DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6850

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • This antibody is not cross-reactive with other tyrosine-phosphorylated protein tyrosine kinases
  • Spleen tyrosine kinase (SYK), along with ZAP70, are cytoplasmic tyrosine kinases that are viewed as potential druge targets for allergic disorders and autoimmune diseases
  • SYK may also play a role in cancer
  • Syk translocates to the plasma membrane upon B cell antigen receptor (BCR) or the high-affinity IgE receptor (FcepsilonRI) triggering, and phosphorylates downstream adaptor proteins, thereby providing docking sites for initiation of subsequent signaling pathways, such as calcium mobilization, cytoskeleton remodeling, or transcription of specific genes
  • Syk binds to the receptor assemblies through interactions of its pair of SH2 domains with ITAM motives of the receptor, which have been phosphorylated by Src-family kinases
  • These kinases also help to activate Syk by phosphorylation of its activation loop.

Compare Similar Items

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Img

Thermo Scientific

PIMA514918

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Antigen:
Phospho-Syk (Tyr525, Tyr526)

Classification:
Monoclonal

Concentration:
90 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P43405

Gene Symbols:
Syk

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr525/526 of human Syk

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
F.724.5

Conjugate:
Unconjugated

Gene:
Syk

Gene Alias:
DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6850

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514919

--


Antigen:
CRTC3

Classification:
Monoclonal

Concentration:
168 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
Q6UUV7, Q91X84

Gene Symbols:
Crtc3

Immunogen:
Synthetic peptide corresponding to the sequence of human TORC3 (CRTC3) protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
R.185.4

Conjugate:
Unconjugated

Gene:
Crtc3

Gene Alias:
2610312F20Rik; 6332415K15Rik; AI429792; BC011210; CREB regulated transcription coactivator 3; CREB-regulated transcription coactivator 3; Crtc3; RGD1309666; TORC3; TORC-3; transducer of CREB protein 3; transducer of regulated cAMP response element-binding protein (CREB) 3; transducer of regulated cAMP response element-binding protein 3; transducer of regulated CREB protein 3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
365297, 64784, 70461

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514920

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Antigen:
Phospho-STAT6 (Tyr641)

Classification:
Monoclonal

Concentration:
103 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P42226

Gene Symbols:
STAT6

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr641 of human Stat6

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
J.187.3

Conjugate:
Unconjugated

Gene:
STAT6

Gene Alias:
12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6778

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514921

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Antigen:
AID

Classification:
Monoclonal

Concentration:
40 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
Q9GZX7

Gene Symbols:
Aicda

Immunogen:
Synthetic peptide corresponding to residues surrounding Leu165 of human AID

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Clone:
K.15.2

Conjugate:
Unconjugated

Gene:
Aicda

Gene Alias:
activation induced deaminase; activation-induced cytidine deaminase; Aicda; AID; Arp2; CDA2; Cytidine aminohydrolase; epididymis secretory protein Li 284; HEL-S-284; HIGM2; integrated into Burkitt's lymphoma cell line Ramos; single-stranded DNA cytosine deaminase

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57379

Content And Storage:
-20°C

Form:
Liquid