PIMA515434

Axl Monoclonal Antibody (1B3A2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515434-Each-of-1 In Stock ₹ 48,127.50

PIMA515434 - Each of 1

₹ 48,127.50

In Stock

Quantity

1

Base Price: ₹ 48,127.50

GST (18%): ₹ 8,662.95

Total Price: ₹ 56,790.45

Antigen

Axl

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

P30530

Gene Symbols

AXL

Immunogen

Purified recombinant fragment of AXL(aa466-530) expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

558

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Western Blot

Clone

1B3A2

Conjugate

Unconjugated

Gene

AXL

Gene Alias

Adhesion-related kinase; AI323647; ARK; AXL; AXL oncogene; AXL receptor tyrosine kinase; AXL transforming sequence/gene; AZF1; JTK11; oncogene AXL; sAXL; soluble AXL; Tyro7; Tyrosine-protein kinase receptor UFO; Ufo; ufo oncogene homolog

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15434 targets AXL in indirect ELISA, WB applications and shows reactivity with Human samples
  • The MA5-15434 immunogen is purified recombinant fragment of AXL(aa466-530) expressed in E
  • Coli
  • AXL is a chronic myelogenous leukemia-associated oncogene that is also associated with colon cancer and melanoma
  • The AXL protein is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6, and is involved in the stimulation of cell proliferation
  • TAM receptors are also involved in phagocytosis of apoptotic cells
  • Mice lacking all three TAM receptors have several degenerative phenotypes linked to inefficient removal of apoptotic cells and membranes (e.g., in the retina and the male reproductive tract) and develop a severe autoimmune phenotype akin to systemic lupus erythematosus, including the production of broad spectrum auto-antibodies
  • In addition, Axl may function as a putative entry receptor for filoviruses
  • Axl is also used to identify a specific subpopulation of human blood dendritic cells, also referred to as Siglec 6+/Axl+ dendritic cells
  • Cellular expression of Axl can be upregulated by TLR ligands, such as LPS or poly I:C
  • Soluble Axl is generated by proteolytic cleavage of the membrane form
  • Increased plasma levels may be indicative of inflammation and cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA515434

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Antigen:
Axl

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P30530

Gene Symbols:
AXL

Immunogen:
Purified recombinant fragment of AXL(aa466-530) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
558

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
1B3A2

Conjugate:
Unconjugated

Gene:
AXL

Gene Alias:
Adhesion-related kinase; AI323647; ARK; AXL; AXL oncogene; AXL receptor tyrosine kinase; AXL transforming sequence/gene; AZF1; JTK11; oncogene AXL; sAXL; soluble AXL; Tyro7; Tyrosine-protein kinase receptor UFO; Ufo; ufo oncogene homolog

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515436

--


Antigen:
HAND1

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
O96004

Gene Symbols:
HAND1

Immunogen:
Purified recombinant fragment of HAND1 (aa90-190) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
9421

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
8E7A11,8C2F4, 8C2F4

Conjugate:
Unconjugated

Gene:
HAND1

Gene Alias:
bHLHa27; Class A basic helix-loop-helix protein 27; eHAND; Ehand1; extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1; HAND1; heart and neural crest derivatives expressed 1; heart and neural crest derivatives expressed transcript 1; heart- and neural crest derivatives-expressed protein 1; Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast; Hxt; Th1; Thing1; thing-1

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515437

--


Antigen:
ErbB3

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P21860

Gene Symbols:
ERBB3

Immunogen:
Purified recombinant fragment of ERBB3 (aa1175-1275) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
2065

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
3F10F6

Conjugate:
Unconjugated

Gene:
ERBB3

Gene Alias:
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515439

--


Antigen:
HPV Type 16 E7

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Purified recombinant full-lenght E7 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
3D6F1

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
HPV 16-E7; HPV16E7; human papillomavirus

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG1