PIMA514899

TNFR1 Monoclonal Antibody (B.34.10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA514899-Each-of-1 In Stock ₹ 45,132.90

PIMA514899 - Each of 1

₹ 45,132.90

In Stock

Quantity

1

Base Price: ₹ 45,132.90

GST (18%): ₹ 8,123.922

Total Price: ₹ 53,256.822

Antigen

TNFR1

Classification

Monoclonal

Concentration

29 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P19438

Gene Symbols

Tnfrsf1a

Immunogen

Synthetic peptide corresponding to residues within the intracellular region and surrounding Ser331 of human TNF-R1 protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunoprecipitation, Western Blot

Clone

B.34.10

Conjugate

Unconjugated

Gene

Tnfrsf1a

Gene Alias

CD120a; CD120a antigen; FPF; hypothetical protein; metalloproteinase inhibitor 4; MGC19588; MS5; n-smase activation assoc. factor; p55; p55 TNF receptor; p55-R; p60; p62; p63; sCD120a; soluble CD120a; soluble TNFR1; sTNF RI; sTNFR I; sTNFR1; sTNFRI; TBP1; TBPI; TIMP metallopeptidase inhibitor 4; Timp4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4; TNF receptor alpha chain; TNF receptor superfamily member 1A; TNF-alphaR1; TNF-alpha-R1; TNFalpha-R1; TNFAR; TNFR; TNF-R; TNFR I; TNFR1; TNF-R1; Tnfr-1; TNFR1-d2; Tnfr-2; TNFR55; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRp55; Tnfrsf1a; tumor necrosis factor binding protein 1; Tumor necrosis factor receptor; tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor superfamily member 1A, membrane form; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type 1; tumor necrosis factor receptor type I; tumor necrosis factor-alpha receptor; Tumor necrosis factor-binding protein 1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7132

Content And Storage

-20°C

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA531264

--

Img

Novus Biologicals

NB512766

--

Img

Thermo Scientific

PIMA544021

--

Img

Novus Biologicals

NB108799

--

Img

Novus Biologicals

NB471936

--

Img

Novus Biologicals

NB471931

--

Img

Novus Biologicals

NB080270

--

Img

Novus Biologicals

NB080266

--

Description

  • It is not recommended to aliquot this antibody
  • TNFR1 (Tumor necrosis factor receptor 1) belongs to the tumor necrosis factor superfamily, and is one of the major TNF-alpha receptors
  • TNFR1 plays an important role in mediating, in cytokine mediated signaling, positive regulation of the NF-Kb pathway, positive regulation of angiogenesis, and negative regulation of gene expression
  • The extracellular domain of TNFR1 is also released into the circulatory system as soluble TNFR1 (sTNFR1)
  • In humans, the TNFR1 gene is located on chromosome 12
  • Anti-apoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with TNFR1, and thus play regulatory roles in the signal transduction mediated by the receptor
  • Germline mutations of the extracellular domains of TNFR1 were found to be associated with the autosomal dominant periodic fever syndrome, and the impaired receptor clearance is thought to be a mechanism of the disease.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA514899

--


Antigen:
TNFR1

Classification:
Monoclonal

Concentration:
29 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P19438

Gene Symbols:
Tnfrsf1a

Immunogen:
Synthetic peptide corresponding to residues within the intracellular region and surrounding Ser331 of human TNF-R1 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Clone:
B.34.10

Conjugate:
Unconjugated

Gene:
Tnfrsf1a

Gene Alias:
CD120a; CD120a antigen; FPF; hypothetical protein; metalloproteinase inhibitor 4; MGC19588; MS5; n-smase activation assoc. factor; p55; p55 TNF receptor; p55-R; p60; p62; p63; sCD120a; soluble CD120a; soluble TNFR1; sTNF RI; sTNFR I; sTNFR1; sTNFRI; TBP1; TBPI; TIMP metallopeptidase inhibitor 4; Timp4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4; TNF receptor alpha chain; TNF receptor superfamily member 1A; TNF-alphaR1; TNF-alpha-R1; TNFalpha-R1; TNFAR; TNFR; TNF-R; TNFR I; TNFR1; TNF-R1; Tnfr-1; TNFR1-d2; Tnfr-2; TNFR55; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRp55; Tnfrsf1a; tumor necrosis factor binding protein 1; Tumor necrosis factor receptor; tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor superfamily member 1A, membrane form; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type 1; tumor necrosis factor receptor type I; tumor necrosis factor-alpha receptor; Tumor necrosis factor-binding protein 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7132

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514902

--


Antigen:
NUMB

Classification:
Monoclonal

Concentration:
352 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P49757, Q2LC84, Q9QZS3

Gene Symbols:
Numb

Immunogen:
Synthetic peptide corresponding to residues surrounding Ala570 of human Numb protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot, Western Blot

Clone:
T.873.4

Conjugate:
Unconjugated

Gene:
Numb

Gene Alias:
c14_5527; C14orf41; h-Numb; mnb; m-Nb; m-numb; Nb; NUMB; NUMB endocytic adaptor protein; numb gene homolog; numb gene homolog (Drosophila); numb homolog; numb homolog (Drosophila); NUMB isoform 3; Numb variant 1; Numb variant 2; NUMB, endocytic adaptor protein; protein numb homolog; Protein S171; PTB domain protein; S171

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18222, 29419, 8650

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514903

--


Antigen:
TrkB

Classification:
Monoclonal

Concentration:
10 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P15209, Q16620, Q63604

Gene Symbols:
Ntrk2

Immunogen:
Synthetic peptide surrounding Pro50 of human TrkB

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
J.977.7

Conjugate:
Unconjugated

Gene:
Ntrk2

Gene Alias:
AI848316; BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; C030027L06Rik; EC 2.7.10.1; GP145 TrkB; GP145TrkB; GP145-TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; GP95-TrkB; hyperphagia; kinase TrkB; neural receptor protein-tyrosine kinase (trkB); neurotrophic receptor tyrosine kinase 2; neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; NTRK 2; Ntrk2; OTTHUMP00000021573; OTTHUMP00000021574; OTTHUMP00000021576; OTTHUMP00000021577; RATTRKB1; Tkrb; Trk B; TRKB; trk-B; trkB protein; trkB tyrosine kinase; TRKB1; Tropomyosin-related kinase B; tyrosine kinase receptor B

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18212, 25054, 4915

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514904

--


Antigen:
Phospho-Aurora A (Thr288)

Classification:
Monoclonal

Concentration:
334 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
O14965

Gene Symbols:
AURKA

Immunogen:
Synthetic phosphopeptide corresponding to residues around pThr288 of human Aurora A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
F.131.2

Conjugate:
Unconjugated

Gene:
AURKA

Gene Alias:
Aik; Airk; AIRK1; Ark1; ARK-1; AU019385; AURA; AURAK; AURKA; Aurora 2; aurora A; Aurora A Kinase; aurora family kinase 1; Aurora kinase A; aurora/IP; aurora/IPL1-like kinase; aurora/IPL1-related kinase 1; AURORA2; Aurora-A; aurora-related kinase 1; AW539821; Ayk1; Breast tumor-amplified kinase; BTAK; EC 2.7.11.1; hARK1; IAK; IAK1; Ipl1- and aurora-related kinase 1; IPL1-related kinase; MGC34538; OTTHUMP00000031341; OTTHUMP00000166072; PPP1R47; protein phosphatase 1, regulatory subunit 47; ratAurA; RP5-1167H4.6; sereine threonine kinase; serine/threonine kinase 6; serine/threonine protein kinase 15; serine/threonine protein kinase 6; serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; serine/threonine-protein kinase 6; aurora kinase A; serine/threonine-protein kinase aurora-A; Serine/threonine-protein kinase Ayk1; STK15; STK6; STK7; Unknown (protein for MGC:134472)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6790

Content And Storage:
-20°C

Form:
Liquid