PIMA514902

NUMB Monoclonal Antibody (T.873.4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA514902-Each-of-1 In Stock ₹ 43,165.02

PIMA514902 - Each of 1

₹ 43,165.02

In Stock

Quantity

1

Base Price: ₹ 43,165.02

GST (18%): ₹ 7,769.704

Total Price: ₹ 50,934.724

Antigen

NUMB

Classification

Monoclonal

Concentration

352 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P49757, Q2LC84, Q9QZS3

Gene Symbols

Numb

Immunogen

Synthetic peptide corresponding to residues surrounding Ala570 of human Numb protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot, Western Blot

Clone

T.873.4

Conjugate

Unconjugated

Gene

Numb

Gene Alias

c14_5527; C14orf41; h-Numb; mnb; m-Nb; m-numb; Nb; NUMB; NUMB endocytic adaptor protein; numb gene homolog; numb gene homolog (Drosophila); numb homolog; numb homolog (Drosophila); NUMB isoform 3; Numb variant 1; Numb variant 2; NUMB, endocytic adaptor protein; protein numb homolog; Protein S171; PTB domain protein; S171

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18222, 29419, 8650

Content And Storage

-20°C

Form

Liquid

Related Products

Img

Thermo Scientific

PIPA521143

--

Img

Thermo Scientific

PIPA5102585

--

Img

Thermo Scientific

PIPA5104540

--

Img

Novus Biologicals

NB319467

--

Img

Thermo Scientific

PIPA5106332

--

Img

Thermo Scientific

PIPA5101681

--

Img

Thermo Scientific

PIPA5112625

--

Img

Thermo Scientific

PIPA5106317

--

Description

  • It is not recommended to aliquot this antibody
  • Protein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells
  • Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex
  • NUMB is also expressed in postmitotic neurons and plays a role in axonal growth
  • Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA514902

--


Antigen:
NUMB

Classification:
Monoclonal

Concentration:
352 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P49757, Q2LC84, Q9QZS3

Gene Symbols:
Numb

Immunogen:
Synthetic peptide corresponding to residues surrounding Ala570 of human Numb protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot, Western Blot

Clone:
T.873.4

Conjugate:
Unconjugated

Gene:
Numb

Gene Alias:
c14_5527; C14orf41; h-Numb; mnb; m-Nb; m-numb; Nb; NUMB; NUMB endocytic adaptor protein; numb gene homolog; numb gene homolog (Drosophila); numb homolog; numb homolog (Drosophila); NUMB isoform 3; Numb variant 1; Numb variant 2; NUMB, endocytic adaptor protein; protein numb homolog; Protein S171; PTB domain protein; S171

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18222, 29419, 8650

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514903

--


Antigen:
TrkB

Classification:
Monoclonal

Concentration:
10 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P15209, Q16620, Q63604

Gene Symbols:
Ntrk2

Immunogen:
Synthetic peptide surrounding Pro50 of human TrkB

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
J.977.7

Conjugate:
Unconjugated

Gene:
Ntrk2

Gene Alias:
AI848316; BDNF/NT-3 growth factors receptor; BDNF-tropomyosine receptor kinase B; C030027L06Rik; EC 2.7.10.1; GP145 TrkB; GP145TrkB; GP145-TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; GP95-TrkB; hyperphagia; kinase TrkB; neural receptor protein-tyrosine kinase (trkB); neurotrophic receptor tyrosine kinase 2; neurotrophic tyrosine kinase receptor type 2; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine receptor kinase type 2; NTRK 2; Ntrk2; OTTHUMP00000021573; OTTHUMP00000021574; OTTHUMP00000021576; OTTHUMP00000021577; RATTRKB1; Tkrb; Trk B; TRKB; trk-B; trkB protein; trkB tyrosine kinase; TRKB1; Tropomyosin-related kinase B; tyrosine kinase receptor B

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18212, 25054, 4915

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514904

--


Antigen:
Phospho-Aurora A (Thr288)

Classification:
Monoclonal

Concentration:
334 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
O14965

Gene Symbols:
AURKA

Immunogen:
Synthetic phosphopeptide corresponding to residues around pThr288 of human Aurora A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
F.131.2

Conjugate:
Unconjugated

Gene:
AURKA

Gene Alias:
Aik; Airk; AIRK1; Ark1; ARK-1; AU019385; AURA; AURAK; AURKA; Aurora 2; aurora A; Aurora A Kinase; aurora family kinase 1; Aurora kinase A; aurora/IP; aurora/IPL1-like kinase; aurora/IPL1-related kinase 1; AURORA2; Aurora-A; aurora-related kinase 1; AW539821; Ayk1; Breast tumor-amplified kinase; BTAK; EC 2.7.11.1; hARK1; IAK; IAK1; Ipl1- and aurora-related kinase 1; IPL1-related kinase; MGC34538; OTTHUMP00000031341; OTTHUMP00000166072; PPP1R47; protein phosphatase 1, regulatory subunit 47; ratAurA; RP5-1167H4.6; sereine threonine kinase; serine/threonine kinase 6; serine/threonine protein kinase 15; serine/threonine protein kinase 6; serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; serine/threonine-protein kinase 6; aurora kinase A; serine/threonine-protein kinase aurora-A; Serine/threonine-protein kinase Ayk1; STK15; STK6; STK7; Unknown (protein for MGC:134472)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6790

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA514905

--


Antigen:
Phospho-PDGFRA/PDGFRB (Tyr849, Tyr857)

Classification:
Monoclonal

Concentration:
632 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P05622, P09619, P16234, P20786, P26618, Q05030

Gene Symbols:
PDGFRA, PDGFRB

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr857 of human PDGF receptor β

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Clone:
T.564.8

Conjugate:
Unconjugated

Gene:
PDGFRB

Gene Alias:
AI115593; AI528809; alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); alpha-type platelet-derived growth factor receptor; APDGFR; beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140 antigen-like family member B; CD140a; CD140a antigen; CD140b; GAS9; IBGC4; IMF1; JTK12; KOGS; MGC74795; PDGF alpha chain; PDGF beta chain; PDGF Receptor alpha; PDGFACE; PDGFR; PDGFR1; PDGFR-1; PDGFR2; PDGFR-2; Pdgfra; pdgfr-a; PDGFRA/BCR fusion; PDGF-R-alpha; PDGFR-alpha; Pdgfrb; PDGF-R-beta; PDGFR-beta; PENTT; PGFRB; platelet derived growth factor receptor alpha; platelet derived growth factor receptor beta; platelet derived growth factor receptor, alpha polypeptide; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 1; platelet-derived growth factor receptor

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18595, 18596, 24629, 25267, 5156, 5159

Content And Storage:
-20°C

Form:
Liquid