PIPA5102585

NUMBL Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102585-Each-of-1 In Stock ₹ 44,705.10

PIPA5102585 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

NUMBL

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Numbl

Gene Alias

CAG3A; CTG3a; NBL; numb homolog (Drosophila)-like; numb homolog-like; NUMB like, endocytic adaptor protein; Numbl; NUMBLIKE; numb-like; numb-like protein; NUMBR; Numb-R; numb-related protein; TNRC23

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18223, 292732, 9253

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

A1L1I3, O08919, Q9Y6R0

Gene Symbols

Numbl

Immunogen

A synthesized peptide derived from human NUMBL(Accession Q9Y6R0), corresponding to amino acid residues L533-A583.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total NUMBL
  • Plays a role in the process of neurogenesis
  • Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate
  • Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis
  • Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity
  • Negative regulator of NF-kappa-B signaling pathway
  • The inhibition of NF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons
  • [UniProt]

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Img

Thermo Scientific

PIPA5102585

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Antigen:
NUMBL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Numbl

Gene Alias:
CAG3A; CTG3a; NBL; numb homolog (Drosophila)-like; numb homolog-like; NUMB like, endocytic adaptor protein; Numbl; NUMBLIKE; numb-like; numb-like protein; NUMBR; Numb-R; numb-related protein; TNRC23

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18223, 292732, 9253

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
A1L1I3, O08919, Q9Y6R0

Gene Symbols:
Numbl

Immunogen:
A synthesized peptide derived from human NUMBL(Accession Q9Y6R0), corresponding to amino acid residues L533-A583.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102586

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Antigen:
GAS2L1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GAS2L1

Gene Alias:
4930500E24Rik; D0Jmb1; Gar22; GAS2L1; GAS2-like protein 1; GAS2-related protein; GAS2-related protein on chromosome 22; growth arrest specific 2 like 1; growth arrest-specific 2 like 1; growth arrest-specific protein 2-like 1; TU-71.1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10634, 360973, 78926

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8JZP9, Q99501

Gene Symbols:
GAS2L1

Immunogen:
A synthesized peptide derived from human GAS2L1(Accession Q99501), corresponding to amino acid residues C624-R674.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102587

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Antigen:
MALT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MALT1

Gene Alias:
A630046N12; caspase-like protein; D430033E09Rik; DKFZp434L132; IMD12; MALT lymphoma-associated translocation; Malt1; malt-1; MALT1 paracaspase; MALT1 protease; MLT; MLT1; mucosa associated lymphoid tissue lymphoma translocation gene 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; paracaspase; paracaspase 1; paracaspase-1; PCASP1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10892, 240354, 307366

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q2TBA3, Q9UDY8

Gene Symbols:
MALT1

Immunogen:
A synthesized peptide derived from human MALT1(Accession Q9UDY8), corresponding to amino acid residues C317-Y367.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102589

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Antigen:
SCCPDH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCCPDH

Gene Alias:
AW214504; C330023F11Rik; CGI 49; CGI49; CGI-49; hypothetical protein LOC507289; NET11; probable saccharopine dehydrogenase; RGD1311440; RP11-439E19.2; saccharopine dehydrogenase (putative); saccharopine dehydrogenase-like oxidoreductase; Sccpdh; SCPDH

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
109232, 305021, 51097

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6AY30, Q8NBX0, Q8R127

Gene Symbols:
SCCPDH

Immunogen:
A synthesized peptide derived from human SCCPDH(Accession Q8NBX0), corresponding to amino acid residues L130-F180.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG