PIMA515431

MLH1 Monoclonal Antibody (4C9C7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515431-Each-of-1 In Stock ₹ 53,560.56

PIMA515431 - Each of 1

₹ 53,560.56

In Stock

Quantity

1

Base Price: ₹ 53,560.56

GST (18%): ₹ 9,640.901

Total Price: ₹ 63,201.461

Antigen

MLH1

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

P40692

Gene Symbols

Mlh1

Immunogen

Purified recombinant fragment of MLH1 (aa381-483) expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

4292

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

4C9C7

Conjugate

Unconjugated

Gene

Mlh1

Gene Alias

1110035C23Rik; AI317206; AI325952; AI561766; COCA2; colon cancer, nonpolyposis type 2; DNA mismatch repair protein Mlh1; DNA mismatch repair protein Mlh1-like protein; FCC2; hMLH1; HNPCC; HNPCC2; I79_014127; MGC5172; mismatch repair protein 1; MLH1; MLH-1; mutL homolog 1; mutL homolog 1 (E. coli); mutL homolog 1, colon cancer, nonpolyposis type 2; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); mutL protein homolog 1

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15431 targets MLH1 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human and Non-human primate samples
  • The MA5-15431 immunogen is purified recombinant fragment of MLH1 (aa381-483) expressed in E
  • Coli.<br>
  • MA5-15431 detects MLH1 which has a predicted molecular weight of approximately 85kDa
  • MLH1 is a DNA mismatch repair protein
  • The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time
  • An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI)
  • These defects in DNA repair pathways have been related to human carcinogenesis
  • The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC)
  • MSHS2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process
  • It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA515431

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Antigen:
MLH1

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P40692

Gene Symbols:
Mlh1

Immunogen:
Purified recombinant fragment of MLH1 (aa381-483) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
4292

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
4C9C7

Conjugate:
Unconjugated

Gene:
Mlh1

Gene Alias:
1110035C23Rik; AI317206; AI325952; AI561766; COCA2; colon cancer, nonpolyposis type 2; DNA mismatch repair protein Mlh1; DNA mismatch repair protein Mlh1-like protein; FCC2; hMLH1; HNPCC; HNPCC2; I79_014127; MGC5172; mismatch repair protein 1; MLH1; MLH-1; mutL homolog 1; mutL homolog 1 (E. coli); mutL homolog 1, colon cancer, nonpolyposis type 2; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); mutL protein homolog 1

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515434

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Antigen:
Axl

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P30530

Gene Symbols:
AXL

Immunogen:
Purified recombinant fragment of AXL(aa466-530) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
558

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
1B3A2

Conjugate:
Unconjugated

Gene:
AXL

Gene Alias:
Adhesion-related kinase; AI323647; ARK; AXL; AXL oncogene; AXL receptor tyrosine kinase; AXL transforming sequence/gene; AZF1; JTK11; oncogene AXL; sAXL; soluble AXL; Tyro7; Tyrosine-protein kinase receptor UFO; Ufo; ufo oncogene homolog

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515436

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Antigen:
HAND1

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
O96004

Gene Symbols:
HAND1

Immunogen:
Purified recombinant fragment of HAND1 (aa90-190) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
9421

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
8E7A11,8C2F4, 8C2F4

Conjugate:
Unconjugated

Gene:
HAND1

Gene Alias:
bHLHa27; Class A basic helix-loop-helix protein 27; eHAND; Ehand1; extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1; HAND1; heart and neural crest derivatives expressed 1; heart and neural crest derivatives expressed transcript 1; heart- and neural crest derivatives-expressed protein 1; Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast; Hxt; Th1; Thing1; thing-1

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515437

--


Antigen:
ErbB3

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P21860

Gene Symbols:
ERBB3

Immunogen:
Purified recombinant fragment of ERBB3 (aa1175-1275) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
2065

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
3F10F6

Conjugate:
Unconjugated

Gene:
ERBB3

Gene Alias:
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1