PIMA515466

Synaptotagmin 1 Monoclonal Antibody (8G11B10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515466-Each-of-1 In Stock ₹ 47,870.82

PIMA515466 - Each of 1

₹ 47,870.82

In Stock

Quantity

1

Base Price: ₹ 47,870.82

GST (18%): ₹ 8,616.748

Total Price: ₹ 56,487.568

Antigen

Synaptotagmin 1

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

P21579

Gene Symbols

Syt1

Immunogen

Purified recombinant fragment of SYT1 expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

6857

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Western Blot

Clone

8G11B10

Conjugate

Unconjugated

Gene

Syt1

Gene Alias

AW124717; DKFZp781D2042; FLJ42519; G630098F17Rik; P65; SV DKFZp781D2042; SV SYT; svp65; Syb1; synaptotagmin 1; synaptotagmin 1 L homeolog; synaptotagmin 2; synaptotagmin I; synaptotagmin I protein; synaptotagmin I variant b; Synaptotagmin II; Synaptotagmin XI; synaptotagmin-1; Synaptotagmin-2; SYT; Syt1; syt1.L; SYT2; SytI; SytII; XELAEV_18022019mg

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15466 targets SYT1 in indirect ELISA, WB applications and shows reactivity with Human samples
  • The MA5-15466 immunogen is purified recombinant fragment of SYT1 expressed in E
  • Coli
  • <br>
  • Synaptotagmin 1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release
  • Studies indicate that synaptotagmin’s Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane
  • It has been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size
  • Synaptotagmin 1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse
  • Further, Synaptotagmin 1 binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone
  • A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has been reported
  • Synaptotagmin 1 can also bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2
  • Diseases associated with the dysfunction of Synaptotagmin 1 include food-borne botulism and infant botulism.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA515466

--


Antigen:
Synaptotagmin 1

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P21579

Gene Symbols:
Syt1

Immunogen:
Purified recombinant fragment of SYT1 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
6857

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
8G11B10

Conjugate:
Unconjugated

Gene:
Syt1

Gene Alias:
AW124717; DKFZp781D2042; FLJ42519; G630098F17Rik; P65; SV DKFZp781D2042; SV SYT; svp65; Syb1; synaptotagmin 1; synaptotagmin 1 L homeolog; synaptotagmin 2; synaptotagmin I; synaptotagmin I protein; synaptotagmin I variant b; Synaptotagmin II; Synaptotagmin XI; synaptotagmin-1; Synaptotagmin-2; SYT; Syt1; syt1.L; SYT2; SytI; SytII; XELAEV_18022019mg

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515467

--


Antigen:
Laminin beta-1

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P07942

Gene Symbols:
LAMB1

Immunogen:
Purified recombinant fragment of LAMB1 (aa31-270) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
3912

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Western Blot

Clone:
2D9G5

Conjugate:
Unconjugated

Gene:
LAMB1

Gene Alias:
C77966; C80098; C81607; CLM; D130003D08Rik; I79_017505; LAMB1; Lamb-1; LAMB1; basement membrane protein; Lamb1-1; laminin B1; laminin B1 chain; laminin B1 subunit 1; laminin beta 1; laminin beta-1 chain; laminin subunit beta 1; laminin subunit beta-1; laminin, beta 1; laminin-1 subunit beta; Laminin-10 subunit beta; laminin-12 subunit beta; Laminin-2 subunit beta; laminin-6 subunit beta; Laminin-8 subunit beta; LIS5; LOW QUALITY PROTEIN: laminin subunit beta-1; MGC142015

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Img

Thermo Scientific

PIMA515469

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Antigen:
Nanog

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
Q9H9S0

Gene Symbols:
NANOG

Immunogen:
Purified recombinant fragment of NANOG (aa20-166) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
79923

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
1E6C4

Conjugate:
Unconjugated

Gene:
NANOG

Gene Alias:
2410002E02Rik; early embryo specific expression NK family; early embryo specific expression NK-type homeobox protein; Ecat4; ENK; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog; Nanog homeobox

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515470

--


Antigen:
SKP2

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
Q13309

Gene Symbols:
SKP2

Immunogen:
Purified recombinant fragment of SKP2 (aa1-130) expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
6502

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
6G9D10

Conjugate:
Unconjugated

Gene:
SKP2

Gene Alias:
4930500A04Rik; CDK2/cyclin A-associated protein p45; cyclin A/CDK2-associated protein p45; Cyclin-A/CDK2-associated protein p45; FBL1; F-box protein Skp2; F-box/LRR-repeat protein 1; F-box/WD-40 protein 1; FBXL1; FLB1; FWD1; MGC1366; OTTHUMP00000221389; p45; p45skp2; RGD1562456; Skp2; S-phase kinase-associated protein 2; S-phase kinase-associated protein 2 (p45); S-phase kinase-associated protein 2, E3 ubiquitin protein ligase

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1