PIMA515561

JAK3 Monoclonal Antibody (5H2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515561-Each-of-1 In Stock ₹ 50,694.30

PIMA515561 - Each of 1

₹ 50,694.30

In Stock

Quantity

1

Base Price: ₹ 50,694.30

GST (18%): ₹ 9,124.974

Total Price: ₹ 59,819.274

Antigen

JAK3

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

P52333, Q62137

Gene Symbols

JAK3

Immunogen

Purified recombinant fragment of human JAK3 expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

16453, 3718

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Western Blot

Clone

5H2

Conjugate

Unconjugated

Gene

JAK3

Gene Alias

Breast-JAK3; fae; JAK3; JAK-3; JAK3_HUMAN; JAK3B; JAKL; Janus kinase 3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); Janus kinase 3 protein-tyrosine kinase; Janus kinase 3, protein-tyrosine kinase; L JAK; Leukocyte janus kinase; LJAK; L-JAK; RATJAK3; Tyrosine-protein kinase JAK3; wil

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

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Description

  • MA5-15561 targets JAK3 in indirect ELISA, FACS, IF, and WB applications and shows reactivity with Human and mouse samples
  • The MA5-15561 immunogen is purified recombinant fragment of human JAK3 expressed in E
  • Coli
  • MA5-15561 detects JAK3 which has a predicted molecular weight of approximately 125kDa
  • Janus kinase 3 (JAK3) phosphorylates members of the STAT (signal transduction and activators of transcription) family
  • JAK3 is predominantly expressed in immune cells and transduces a signal in response to activation of interleukin receptors
  • In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • However, active JAK1 may be required for complex responses
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex.

Compare Similar Items

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Img

Thermo Scientific

PIMA515561

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Antigen:
JAK3

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
P52333, Q62137

Gene Symbols:
JAK3

Immunogen:
Purified recombinant fragment of human JAK3 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
16453, 3718

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
5H2

Conjugate:
Unconjugated

Gene:
JAK3

Gene Alias:
Breast-JAK3; fae; JAK3; JAK-3; JAK3_HUMAN; JAK3B; JAKL; Janus kinase 3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); Janus kinase 3 protein-tyrosine kinase; Janus kinase 3, protein-tyrosine kinase; L JAK; Leukocyte janus kinase; LJAK; L-JAK; RATJAK3; Tyrosine-protein kinase JAK3; wil

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515563

--


Antigen:
NFkB p65

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.03% sodium azide

Gene Accession No.:
Q04206, Q04207

Gene Symbols:
RELA

Immunogen:
Purified recombinant fragment of human NF-κB p65 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
19697, 5970

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Clone:
6H7

Conjugate:
Unconjugated

Gene:
RELA

Gene Alias:
avian reticuloendotheliosis viral (v-rel) oncogene homolog A; EBP-1; I79_021812; MGC131774; NF KB; NFkappaB p65; nf-kappa-b p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NF-kappaB transcription factor p65 subunit; NFkB; NF-kB p65 subunit; nfkb rela; NFKB1; nfkb3; NFkB-p50; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit p65; nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; P65 transcription factor; putative transcription factor p65 homolog; REL A; rel1; rela; RELA proto-oncogene, NF-kB subunit; rela.L; rela-a; Transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65; XELAEV_18022301mg; Xrel1; xrela

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

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PIMA515564

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Antigen:
Metadherin

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% sodium azide

Gene Accession No.:
Q86UE4

Gene Symbols:
MTDH

Immunogen:
Purified recombinant fragment of human Metadherin expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
92140

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunohistochemistry, Western Blot

Clone:
2F11C3

Conjugate:
Unconjugated

Gene:
MTDH

Gene Alias:
2610103J23Rik; 3D3; 3D3/Lyric; AEG1; AEG-1; astrocyte elevated gene 1; astrocyte elevated gene-1 protein; AV353288; D8Bwg1112e; LYRIC; LYRIC/ MTDH; LYRIC/3D3; lysine-rich CEACAM1 co-isolated protein; Metadherin; metastasis adhesion protein; MTDH; Protein LYRIC

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

PIMA515565

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Antigen:
DDX4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q9NQI0

Gene Symbols:
DDX4

Immunogen:
Purified recombinant fragment of human DDX4 expressed in E. Coli.

Regulatory Status:
RUO

Gene ID (Entrez):
54514

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
2F9H5

Conjugate:
Unconjugated

Gene:
DDX4

Gene Alias:
ATP-dependent RNA helicase DDX4; AV206478; Cvh; Ddx4; D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 4; DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 4; DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; DEAD box polypeptide 4; DEAD box protein 4; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4; DEAD-box helicase 4; MGC111074; Mvh; mvh / m'vasa; probable ATP-dependent RNA helicase DDX4; putative ATP-dependent RNA helicase DDX4; RVLG; VASA; Vasa homolog; vasa-like gene protein

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1